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Results for the Category
JNK cascade
(GO:0007254)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
RPS27A 4 -1.330 2.560 -0.309 0.131 -0.009
UBC 3 -0.309 0.131 -0.009
UBC 3
UBC 3
UBB 3 -0.309 0.131 -0.009
UBA52 3 -1.260 2.180 -0.309 0.131 -0.009
UBA52 3 -1.260 2.180
TAB3 2 -0.550 1.560 0.022 -0.207
TAB3 2 -0.550 1.560
MAPK9 1 0.110 -0.490
TAB1 1 1.890 -0.670
TAB1 1 1.890 -0.670 1.657
RIPK2 1 -1.740 3.580
DUSP9 1 -2.590 5.800
GPS1 1 0.850 -0.820 1.476 0.259
GPS1 1 0.850 -0.820 0.185
MAPK8IP2 0 1.730 -1.220
RB1CC1 0 -0.320 0.680
RB1CC1 0 -0.320 0.680 -1.155 -0.488
TAB2 0 -0.030 -0.580
MAP2K4 0 -0.300 0.320
IKBKG 0
HACD3 0 0.540 -0.250
HACD3 0 0.540 -0.250 0.188 0.116
MAP2K7 0 0.180 -0.660 -2.110
MAP3K1 0 0.750 -1.270
CRKL 0 0.290 -0.620
WNT5A 0
ARHGEF6 0 0.570 -0.210
ARHGEF6 0 0.570 -0.210
DUSP6 0 0.100 0.300
DUSP7 0 -0.270 0.070
MAP3K7 0 -1.120 1.140 -1.048
MINK1 0 -0.710 0.650 0.038 0.092 0.062
MINK1 0 -0.710 0.650
ROR2 0 0.180 -0.350
ADORA2B 0 -0.080 0.070
TRIB1 0 -0.220 -0.430
MAP3K5 0 0.710 -0.770

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ADORA2B Ubiquitylation K303 0.335 _YTFHK(gl)IISR_
ARHGEF6 Phosphorylation S225 -0.163 -0.076 _SSERPLS(ph)PK_
ARHGEF6 Phosphorylation S415 0.662 0.947 _M(ox)S(ph)GFIYQGK_
ARHGEF6 Phosphorylation S600 0.797 _S(ph)TAALEEDAQILK_
ARHGEF6 Phosphorylation T601 0.797 _S(ph)TAALEEDAQILK_
ARHGEF6 Phosphorylation S684 0.068 -0.061 _KDS(ph)IPQVLLPEEEKLIIEETR_
CRKL Phosphorylation S41 0.868 _DS(ph)STCPGDYVLSVSENSR_
CRKL Phosphorylation S107 -0.818 -1.177 _YPS(ph)PPMGSVSAPNLPTAEDNLEYVR_
DUSP6 Phosphorylation S328 0.484 0.292 _SNIS(ph)PNFNFMGQLLDFER_
DUSP7 Phosphorylation S328 0.484 0.292 _SNIS(ph)PNFNFMGQLLDFER_
DUSP9 Phosphorylation S328 0.484 0.292 _SNIS(ph)PNFNFMGQLLDFER_
GPS1 Ubiquitylation K177 -0.421 _ALLK(gl)LEK_
GPS1 Ubiquitylation K186 -0.059 0.041 _LDTDLK(gl)NYK_
GPS1 Ubiquitylation K189 -0.352 -0.135 _NYK(gl)GNSIK_
GPS1 Ubiquitylation K194 0.155 -0.182 _GNSIK(gl)ESIRR_
GPS1 Ubiquitylation K283 0.835 0.572 _DSQTQAILTK(gl)LK_
GPS1 Ubiquitylation K372 -0.090 _FYESK(gl)YASCLK_
GPS1 Ubiquitylation K457 -0.226 -0.201 _VDSHSK(gl)ILYAR_
GPS1 Ubiquitylation K473 -0.128 0.230 _STTFEK(gl)SLLMGK_
GPS1 Ubiquitylation K479 0.097 _SLLMGK(gl)EFQR_
GPS1 Ubiquitylation K502 -0.539 -1.230 _NQIHVK(gl)SPPREGSQGELTPANSQSR_
GPS1 Phosphorylation S503 -0.084 _NQIHVKS(ph)PPR_
GPS1 Phosphorylation S509 0.192 0.433 _EGS(ph)QGELTPANSQSR_
GPS1 Phosphorylation T514 0.479 0.814 _EGSQGELT(ph)PANS(ph)QSR_
GPS1 Phosphorylation S518 3.914 _EGSQGELT(ph)PANS(ph)QSR_
HACD3 Ubiquitylation K122 0.325 _QVNITVQK(gl)K_
HACD3 Ubiquitylation K123 -0.603 0.819 _K(gl)VSQWWER_
HACD3 Phosphorylation S152 0.751 0.683 _WLDES(ph)DAEM(ox)ELR_
IKBKG Ubiquitylation K285 -1.202 -0.389 _QEVIDKLK(gl)EEAEQHK_
IKBKG Ubiquitylation K309 0.123 0.725 _AQADIYK(gl)ADFQAER_
IKBKG Ubiquitylation K344 0.060 _LK(gl)ASCQESAR_
IKBKG Phosphorylation S387 -1.270 -1.418 _S(ph)PPEEPPDFCCPK_
MAP2K4 Phosphorylation S80 0.441 _LRTHS(ph)IESSGK_
MAP2K7 Ubiquitylation K9 -1.406 _(ac)AASSLEQK(gl)LSR_
MAP2K7 Ubiquitylation K300 -1.228 _GQIK(gl)LCDFGISGR_
MAP2K7 Ubiquitylation K442 -1.326 _DVMAK(gl)TESPR_
MAP3K1 Phosphorylation S292 0.209 _RAPS(ph)PDGFSPYSPEETNR_
MAP3K1 Phosphorylation S506 1.427 _SHDFYSHELS(ph)SPVDSPSSLR_
MAP3K1 Phosphorylation S507 1.436 _SHDFYSHELSS(ph)PVDSPSSLR_
MAP3K1 Phosphorylation S923 0.127 -0.120 _LSAS(ph)SEDISER_
MAP3K5 Phosphorylation S1066 -1.241 _SISLPVPVLVEDTSSSSEYGSVS(ph)PDTELKVDPFSFK_
MAP3K5 Phosphorylation S1113 -1.408 -0.562 _TLFLGIPDENFEDHSAPPS(ph)PEEK_
MAP3K7 Phosphorylation S374 0.149 -0.337 _GS(ph)SVESLPPTSEGK_
MAP3K7 Phosphorylation S375 0.171 -0.087 _GSS(ph)VESLPPTSEGK_
MAP3K7 Phosphorylation S389 1.072 1.445 _RMS(ph)ADMSEIEAR_
MAP3K7 Phosphorylation S439 0.246 0.198 _S(ph)IQDLTVTGTEPGQVSSR_
MAP3K7 Ubiquitylation K474 -0.385 -0.242 _MITTSGPTSEK(gl)PTR_
MAP3K7 Ubiquitylation K589 -0.104 _SLSTYYQQCK(gl)K_
MAP3K7 Ubiquitylation K590 -0.551 0.560 _K(gl)QLEVIR_
MAPK8IP2 Ubiquitylation K674 -0.899 0.671 _DLLGSK(gl)R_
MAPK9 Phosphorylation Y185 3.533 _TACTNFMMTPY(ph)VVTR_
MINK1 Phosphorylation S763 0.045 -0.277 _SDSVLPASHGHLPQAGS(ph)LER_
RB1CC1 Phosphorylation S222 0.084 0.562 _LDS(ph)LPEHEDSEK_
RB1CC1 Phosphorylation S237 -0.464 -0.874 _S(ph)TELVLSPDM(ox)PR_
RB1CC1 Phosphorylation T238 -0.376 -0.874 _S(ph)TELVLSPDM(ox)PR_
RB1CC1 Phosphorylation S257 -0.819 _TTNESLLTS(ph)FPK_
RB1CC1 Phosphorylation S266 0.766 _SVEHVS(ph)PDTADAESGK_
RB1CC1 Phosphorylation S624 -0.685 -0.445 _AAQS(ph)LDEM(ox)SQTITDLLSEQK_
RIPK2 Ubiquitylation K410 -2.810 _AAFCDHK(gl)TTPCSSAIINPLSTAGNSER_
RIPK2 Phosphorylation S531 0.884 0.839 _SPS(ph)LNLLQNK_
RIPK2 Ubiquitylation K538 -2.659 _SPSLNLLQNK(gl)SM_
ROR2 Ubiquitylation K97 0.598 _WLK(gl)NDAPVVQEPR_
ROR2 Ubiquitylation K510 -0.960 _TLK(gl)DKAEGPLREEFR_
ROR2 Ubiquitylation K512 0.282 _DK(gl)AEGPLREEFR_
RPS27A Ubiquitylation K6 1.066 0.995 _MQIFVK(gl)TLTGK_
RPS27A Ubiquitylation K11 -0.488 -0.081 _TLTGK(gl)TITLEVEPSDTIENVKAK(gl)_
RPS27A Ubiquitylation K27 -0.882 -0.159 _TLTGK(gl)TITLEVEPSDTIENVK(gl)AK_
RPS27A Ubiquitylation K29 -1.087 -1.029 _AK(gl)IQDK(gl)EGIPPDQQR_
RPS27A Ubiquitylation K33 -0.736 -0.407 _IQDK(gl)EGIPPDQQR_
RPS27A Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
RPS27A Phosphorylation S57 1.909 0.548 _TLS(ph)DYNIQK_
RPS27A Ubiquitylation K63 0.276 0.299 _TLSDYNIQK(gl)ESTLHLVLR_
RPS27A Ubiquitylation K99 0.109 2.111 _VK(gl)LAVLK_
RPS27A Ubiquitylation K104 0.674 2.102 _LAVLK(gl)YYK_
RPS27A Ubiquitylation K107 2.949 3.611 _YYK(gl)VDENGK(gl)ISR_
RPS27A Ubiquitylation K113 1.572 3.672 _YYK(gl)VDENGK(gl)ISR_
RPS27A Ubiquitylation K152 4.747 4.970 _CCLTYCFNK(gl)PEDK_
RPS27A Ubiquitylation K156 4.809 _CCLTYCFNKPEDK(gl)_
TAB1 Phosphorylation S7 -0.170 0.140 _S(ph)LLQSEQQPSWTDDLPLCHLSGVGSASNR_
TAB1 Phosphorylation S16 -0.138 0.069 _SLLQSEQQPS(ph)WTDDLPLCHLSGVGSASNR_
TAB1 Ubiquitylation K186 -1.015 _SYSADGK(gl)GTESHPPEDSWLK_
TAB1 Ubiquitylation K371 0.032 _LSQLGLDAGK(gl)IK_
TAB1 Ubiquitylation K373 -0.007 _LSQLGLDAGKIK(gl)_
TAB2 Phosphorylation S580 -0.075 _S(ph)NSISQIPSLEEMQQLR_
TAB2 Phosphorylation S582 0.331 _SNS(ph)ISQIPSLEEMQQLR_
TAB2 Ubiquitylation K653 -0.519 -0.200 _SIIK(gl)TPK_
TAB3 Phosphorylation S4 3.009 1.852 _(ac)AQS(ph)SPQLDIQVLHDLR_
TAB3 Phosphorylation S5 3.009 1.852 _(ac)AQS(ph)SPQLDIQVLHDLR_
TRIB1 Ubiquitylation K46 -2.031 -0.877 _LLDADDAAAVAAK(gl)CPR_
UBA52 Ubiquitylation K6 1.066 0.995 _MQIFVK(gl)TLTGK_
UBA52 Ubiquitylation K11 -0.488 -0.081 _TLTGK(gl)TITLEVEPSDTIENVKAK(gl)_
UBA52 Ubiquitylation K27 -0.882 -0.159 _TLTGK(gl)TITLEVEPSDTIENVK(gl)AK_
UBA52 Ubiquitylation K29 -1.087 -1.029 _AK(gl)IQDK(gl)EGIPPDQQR_
UBA52 Ubiquitylation K33 -0.736 -0.407 _IQDK(gl)EGIPPDQQR_
UBA52 Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBA52 Phosphorylation S57 1.909 0.548 _TLS(ph)DYNIQK_
UBA52 Ubiquitylation K63 0.276 0.299 _TLSDYNIQK(gl)ESTLHLVLR_
UBA52 Ubiquitylation K93 0.181 2.418 _YNCDK(gl)MICR_
UBA52 Ubiquitylation K99 0.109 2.111 _VK(gl)LAVLK_
UBA52 Ubiquitylation K104 0.674 2.102 _LAVLK(gl)YYK_
UBA52 Ubiquitylation K107 2.949 3.611 _YYK(gl)VDENGK(gl)ISR_
UBA52 Ubiquitylation K113 1.572 3.672 _YYK(gl)VDENGK(gl)ISR_
UBA52 Ubiquitylation K152 4.747 4.970 _CCLTYCFNK(gl)PEDK_
UBA52 Ubiquitylation K156 4.809 _CCLTYCFNKPEDK(gl)_
UBB Ubiquitylation K6 1.066 0.995 _MQIFVK(gl)TLTGK_
UBB Ubiquitylation K11 -0.488 -0.081 _TLTGK(gl)TITLEVEPSDTIENVKAK(gl)_
UBB Ubiquitylation K27 -0.882 -0.159 _TLTGK(gl)TITLEVEPSDTIENVK(gl)AK_
UBB Ubiquitylation K29 -1.087 -1.029 _AK(gl)IQDK(gl)EGIPPDQQR_
UBB Ubiquitylation K33 -0.736 -0.407 _IQDK(gl)EGIPPDQQR_
UBB Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBB Phosphorylation S57 1.909 0.548 _TLS(ph)DYNIQK_
UBB Ubiquitylation K63 0.276 0.299 _TLSDYNIQK(gl)ESTLHLVLR_
UBB Ubiquitylation K99 0.109 2.111 _VK(gl)LAVLK_
UBB Ubiquitylation K104 0.674 2.102 _LAVLK(gl)YYK_
UBB Ubiquitylation K107 2.949 3.611 _YYK(gl)VDENGK(gl)ISR_
UBB Ubiquitylation K113 1.572 3.672 _YYK(gl)VDENGK(gl)ISR_
UBB Ubiquitylation K152 4.747 4.970 _CCLTYCFNK(gl)PEDK_
UBB Ubiquitylation K156 4.809 _CCLTYCFNKPEDK(gl)_
UBC Ubiquitylation K6 1.066 0.995 _MQIFVK(gl)TLTGK_
UBC Ubiquitylation K11 -0.488 -0.081 _TLTGK(gl)TITLEVEPSDTIENVKAK(gl)_
UBC Ubiquitylation K27 -0.882 -0.159 _TLTGK(gl)TITLEVEPSDTIENVK(gl)AK_
UBC Ubiquitylation K29 -1.087 -1.029 _AK(gl)IQDK(gl)EGIPPDQQR_
UBC Ubiquitylation K33 -0.736 -0.407 _IQDK(gl)EGIPPDQQR_
UBC Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBC Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBC Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBC Phosphorylation S57 1.909 0.548 _TLS(ph)DYNIQK_
UBC Ubiquitylation K63 0.276 0.299 _TLSDYNIQK(gl)ESTLHLVLR_
UBC Ubiquitylation K99 0.109 2.111 _VK(gl)LAVLK_
UBC Ubiquitylation K104 0.674 2.102 _LAVLK(gl)YYK_
UBC Ubiquitylation K107 2.949 3.611 _YYK(gl)VDENGK(gl)ISR_
UBC Ubiquitylation K113 1.572 3.672 _YYK(gl)VDENGK(gl)ISR_
UBC Ubiquitylation K152 4.747 4.970 _CCLTYCFNK(gl)PEDK_
UBC Ubiquitylation K156 4.809 _CCLTYCFNKPEDK(gl)_
WNT5A Ubiquitylation K268 -0.304 _VGDALK(gl)EK_


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