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Query: GPS1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GPS1 1 7.720 0.850 -0.820 1.476 0.259
GPS1 1 7.720 0.850 -0.820 0.185

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GPS1 Phosphorylation S518 3.914 _EGSQGELT(ph)PANS(ph)QSR_
GPS1 Phosphorylation T514 0.479 0.814 _EGSQGELT(ph)PANS(ph)QSR_
GPS1 Ubiquitylation K283 0.835 0.572 _DSQTQAILTK(gl)LK_
GPS1 Phosphorylation S509 0.192 0.433 _EGS(ph)QGELTPANSQSR_
GPS1 Ubiquitylation K473 -0.128 0.230 _STTFEK(gl)SLLMGK_
GPS1 Ubiquitylation K479 0.097 _SLLMGK(gl)EFQR_
GPS1 Ubiquitylation K186 -0.059 0.041 _LDTDLK(gl)NYK_
GPS1 Phosphorylation S503 -0.084 _NQIHVKS(ph)PPR_
GPS1 Ubiquitylation K372 -0.090 _FYESK(gl)YASCLK_
GPS1 Ubiquitylation K189 -0.352 -0.135 _NYK(gl)GNSIK_
GPS1 Ubiquitylation K194 0.155 -0.182 _GNSIK(gl)ESIRR_
GPS1 Ubiquitylation K457 -0.226 -0.201 _VDSHSK(gl)ILYAR_
GPS1 Ubiquitylation K177 -0.421 _ALLK(gl)LEK_
GPS1 Ubiquitylation K502 -0.539 -1.230 _NQIHVK(gl)SPPREGSQGELTPANSQSR_

Background Information for GPS1:


Pubmed-GPS1 »
Uniprot-GPS1 »
Biogrid-GPS1 »
ProteomicsDB-GPS1 »

Tumorportal-GPS1 »
COSMIC-GPS1 »
GenomeRNAi-GPS1 »
Genecards-GPS1


Protein-protein Interactions for GPS1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait COPS7A Cat. description Hein, Mann, Cell 2015
Category members IP bait CUL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CUL3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CUL4A Cat. description Hein, Mann, Cell 2015
Category members IP bait CUL4B Cat. description Hein, Mann, Cell 2015
Category members IP bait DDB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DDB2 Cat. description Hein, Mann, Cell 2015
Category members IP bait DTL Cat. description Hein, Mann, Cell 2015
Category members IP bait LRR1 Cat. description Hein, Mann, Cell 2015
Category members IP bait APBB3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BTBD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COPS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COPS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COPS5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COPS6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COPS7B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COPS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CUL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DCAF11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DCAF4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DET1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBXL14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBXO7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHL10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAGEA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UBE2M Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GPS1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PCI_dom IPR000717 2.22
Category members 26S_proteasome_reg_su-Rpn7 IPR019585 0.11


Protein complexes (CORUM database) featuring GPS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 728 CSA-POLIIa complex Database 1.74
Category members Corum 726 DDB2 complex Database 1.33
Category members Corum 727 CSA complex Database 1.33
Category members Corum 2715 Ubiquitin E3 ligase (CSN1, CSN8, HRT1, SKP1, SKP2, CUL1, CUL2, CUL3) Database 0.61
Category members Corum 2174 COP9 signalosome complex Database 0.48
Category members Corum 2179 CNS-P53 complex Database 0.19


Categories featuring GPS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0008180 COP9 signalosome Database 1.47
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0010388 cullin deneddylation Database 0.25
Category members GO Category GO:0005095 GTPase inhibitor activity Database 0.05
Category members GO Category GO:0000188 inactivation of MAPK activity Database 0
Category members GO Category GO:0007254 JNK cascade Database 0


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