Results for the Category
GTPase inhibitor activity
(GO:0005095)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| IPO5 | 1 | -0.900 | 0.900 | 0.414 | -0.283 | |||
| IPO5 | 1 | -0.900 | 0.900 | -0.176 | 0.413 | 0.268 | ||
| GPS1 | 1 | 0.850 | -0.820 | 1.476 | 0.259 | |||
| GPS1 | 1 | 0.850 | -0.820 | 0.185 | ||||
| RTKN | 0 | 1.030 | -0.280 | |||||
| IQGAP1 | 0 | -0.420 | 0.300 | 0.641 | -0.402 | |||
| IQGAP1 | 0 | -0.420 | 0.300 | 1.363 | 0.406 | 0.007 | ||
| SLIT2 | 0 | -0.940 | 1.740 | -3.112 | -1.071 | |||
| IQGAP2 | 0 | 0.570 | -0.600 | -0.934 | -0.237 | -0.246 | 0.574 | 0.202 |
| CDC42SE1 | 0 | 0.330 | -0.550 | |||||
| ARL2 | 0 | 0.770 | -1.100 | |||||
| ARL2 | 0 | 0.770 | -1.100 | 1.072 | -1.021 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| ARL2 | Ubiquitylation | K9 | -0.349 | _GLLTILKK(gl)_ | |
| ARL2 | Ubiquitylation | K71 | -0.521 | _LNIWDVGGQK(gl)SLR_ | |
| CDC42SE1 | Ubiquitylation | K15 | -1.010 | -0.893 | _LGCCVVEK(gl)PQPK_ |
| GPS1 | Ubiquitylation | K177 | -0.421 | _ALLK(gl)LEK_ | |
| GPS1 | Ubiquitylation | K186 | -0.059 | 0.041 | _LDTDLK(gl)NYK_ |
| GPS1 | Ubiquitylation | K189 | -0.352 | -0.135 | _NYK(gl)GNSIK_ |
| GPS1 | Ubiquitylation | K194 | 0.155 | -0.182 | _GNSIK(gl)ESIRR_ |
| GPS1 | Ubiquitylation | K283 | 0.835 | 0.572 | _DSQTQAILTK(gl)LK_ |
| GPS1 | Ubiquitylation | K372 | -0.090 | _FYESK(gl)YASCLK_ | |
| GPS1 | Ubiquitylation | K457 | -0.226 | -0.201 | _VDSHSK(gl)ILYAR_ |
| GPS1 | Ubiquitylation | K473 | -0.128 | 0.230 | _STTFEK(gl)SLLMGK_ |
| GPS1 | Ubiquitylation | K479 | 0.097 | _SLLMGK(gl)EFQR_ | |
| GPS1 | Ubiquitylation | K502 | -0.539 | -1.230 | _NQIHVK(gl)SPPREGSQGELTPANSQSR_ |
| GPS1 | Phosphorylation | S503 | -0.084 | _NQIHVKS(ph)PPR_ | |
| GPS1 | Phosphorylation | S509 | 0.192 | 0.433 | _EGS(ph)QGELTPANSQSR_ |
| GPS1 | Phosphorylation | T514 | 0.479 | 0.814 | _EGSQGELT(ph)PANS(ph)QSR_ |
| GPS1 | Phosphorylation | S518 | 3.914 | _EGSQGELT(ph)PANS(ph)QSR_ | |
| IPO5 | Ubiquitylation | K436 | 0.087 | _YAACNAVGQMATDFAPGFQK(gl)K_ | |
| IPO5 | Ubiquitylation | K437 | 0.087 | _YAACNAVGQMATDFAPGFQK(gl)K_ | |
| IPO5 | Ubiquitylation | K548 | 1.682 | _HIVENAVQK(gl)ELR_ | |
| IPO5 | Ubiquitylation | K613 | 0.602 | 0.935 | _MCK(gl)ILGK_ |
| IPO5 | Ubiquitylation | K678 | 1.124 | _TAGLEEK(gl)STACQMLVCYAK_ | |
| IPO5 | Ubiquitylation | K712 | -0.098 | _LMVPLLK(gl)_ | |
| IPO5 | Ubiquitylation | K963 | -0.210 | _TK(gl)ENVNATENCISAVGK_ | |
| IQGAP1 | Ubiquitylation | K953 | 0.650 | _NKEQLSDMMMINK(gl)QK_ | |
| IQGAP1 | Ubiquitylation | K959 | 0.713 | 0.074 | _GGLK(gl)ALSK_ |
| IQGAP1 | Ubiquitylation | K1389 | 0.638 | 1.119 | _TILLNTK(gl)R_ |
| IQGAP1 | Ubiquitylation | K1442 | 0.488 | _SK(gl)SVKEDSNLTLQEK_ | |
| IQGAP1 | Phosphorylation | S1443 | 0.392 | 0.273 | _SKS(ph)VKEDSNLTLQEK_ |
| IQGAP1 | Ubiquitylation | K1445 | 0.863 | _SVK(gl)EDSNLTLQEK_ | |
| IQGAP2 | Phosphorylation | S16 | 0.126 | 0.190 | _YGS(ph)IVDDER_ |
| IQGAP2 | Ubiquitylation | K837 | -0.165 | _IGLLVK(gl)NR_ | |
| RTKN | Ubiquitylation | K100 | -2.570 | _EAQVLGK(gl)TSR_ | |
| RTKN | Phosphorylation | S220 | 0.314 | _LSSS(ph)LGR_ | |
| RTKN | Phosphorylation | S242 | -1.726 | _ASLDSAGGSGSS(ph)PILLPTPVVGGPR_ | |
| RTKN | Phosphorylation | S520 | -1.032 | -1.196 | _TFS(ph)LDAVPPDHSPR_ |
| SLIT2 | Ubiquitylation | K72 | -1.544 | _ITK(gl)TDFAGLR_ | |
| SLIT2 | Ubiquitylation | K103 | 0.625 | _GAFQDLK(gl)ELER_ | |
| SLIT2 | Ubiquitylation | K825 | 0.073 | _TFDGLK(gl)SLR_ |
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