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Query: IPO5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
IPO5 1 4.153 -0.900 0.900 0.414 -0.283
IPO5 1 4.153 -0.900 0.900 -0.176 0.413 0.268

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
IPO5 Ubiquitylation K613 0.602 0.935 _MCK(gl)ILGK_
IPO5 Ubiquitylation K712 -0.098 _LMVPLLK(gl)_
IPO5 Ubiquitylation K436 0.087 _YAACNAVGQMATDFAPGFQK(gl)K_
IPO5 Ubiquitylation K437 0.087 _YAACNAVGQMATDFAPGFQK(gl)K_
IPO5 Ubiquitylation K548 1.682 _HIVENAVQK(gl)ELR_
IPO5 Ubiquitylation K678 1.124 _TAGLEEK(gl)STACQMLVCYAK_
IPO5 Ubiquitylation K963 -0.210 _TK(gl)ENVNATENCISAVGK_

Background Information for IPO5:


Pubmed-IPO5 »
Uniprot-IPO5 »
Biogrid-IPO5 »
ProteomicsDB-IPO5 »

Tumorportal-IPO5 »
COSMIC-IPO5 »
GenomeRNAi-IPO5 »
Genecards-IPO5


Protein-protein Interactions for IPO5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HDAC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC59 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL34 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL35 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NOL7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NOL9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF414 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in IPO5
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members HEAT IPR000357 3.83
Category members Importin-beta_N IPR001494 0


Protein complexes (CORUM database) featuring IPO5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring IPO5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_369 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION 0 INF
Category members Pathway Pathway_371 REACTOME_INFLUENZA_LIFE_CYCLE 0 INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0005643 nuclear pore Database 6.58
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0006607 NLS-bearing protein import into nucleus Database 1.48
Category members GO Category GO:0006610 ribosomal protein import into nucleus Database 0.33
Category members GO Category GO:0008565 protein transporter activity Database 0.26
Category members GO Category GO:0008536 Ran GTPase binding Database 0.21
Category members GO Category GO:0005095 GTPase inhibitor activity Database 0.05
Category members GO Category GO:0042307 positive regulation of protein import into nucleus Database 0
Category members GO Category GO:0071230 cellular response to amino acid stimulus Database 0


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