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Results for the Category
inactivation of MAPK activity
(GO:0000188)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
PPP2R1A 1 -0.260 -0.200 0.714 0.973
PPP2R1A 1 -0.260 -0.200 -0.003 -0.196 0.057
PPP2R1A 1 -0.260 -0.200 1.697 1.450 -1.553
PPP2R1B 1 1.240 -0.730 1.697 1.450 -1.553
DUSP9 1 -2.590 5.800
GPS1 1 0.850 -0.820 1.476 0.259
GPS1 1 0.850 -0.820 0.185
CAV1 0 1.150 -0.150
CAV1 0 1.150 -0.150
CAV1 0 1.150 -0.150
DUSP3 0 0.360 -0.500
PPP2CA 0 0.160 -0.540 0.194 0.044 0.215
PPP2CA 0 0.160 -0.540 0.650 1.189
DUSP1 0 0.290 -0.100
DUSP6 0 0.100 0.300
DUSP7 0 -0.270 0.070
RGS3 0 0.530 -0.710
PRKCA 0 0.750 -0.690 0.349 0.585
PRKCA 0 0.750 -0.690
SPRED2 0 0.990 -1.050

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CAV1 Ubiquitylation K5 0.591 0.963 _(ac)SGGK(gl)YVDSEGHLYTVPIR_
CAV1 Phosphorylation S6 0.836 0.688 _(ac)ADELS(ph)EKQVYDAHTK_
CAV1 Ubiquitylation K8 0.244 0.734 _(ac)ADELSEK(gl)QVYDAHTK_
CAV1 Ubiquitylation K26 0.724 0.894 _EQGNIYK(gl)PNNK_
CAV1 Ubiquitylation K30 -0.008 0.317 _EQGNIYKPNNK(gl)AMADELSEK_
CAV1 Ubiquitylation K39 0.690 1.170 _AMADELSEK(gl)QVYDAHTK_
CAV1 Phosphorylation S76 0.607 0.527 _AMADELS(ph)EK_
CAV1 Ubiquitylation K176 -0.259 _INLQK(gl)EI_
DUSP1 Ubiquitylation K97 -0.523 _SAALDGAK(gl)R_
DUSP3 Ubiquitylation K116 -0.586 _AADFIDQALAQK(gl)NGR_
DUSP6 Phosphorylation S328 0.484 0.292 _SNIS(ph)PNFNFMGQLLDFER_
DUSP7 Phosphorylation S328 0.484 0.292 _SNIS(ph)PNFNFMGQLLDFER_
DUSP9 Phosphorylation S328 0.484 0.292 _SNIS(ph)PNFNFMGQLLDFER_
GPS1 Ubiquitylation K177 -0.421 _ALLK(gl)LEK_
GPS1 Ubiquitylation K186 -0.059 0.041 _LDTDLK(gl)NYK_
GPS1 Ubiquitylation K189 -0.352 -0.135 _NYK(gl)GNSIK_
GPS1 Ubiquitylation K194 0.155 -0.182 _GNSIK(gl)ESIRR_
GPS1 Ubiquitylation K283 0.835 0.572 _DSQTQAILTK(gl)LK_
GPS1 Ubiquitylation K372 -0.090 _FYESK(gl)YASCLK_
GPS1 Ubiquitylation K457 -0.226 -0.201 _VDSHSK(gl)ILYAR_
GPS1 Ubiquitylation K473 -0.128 0.230 _STTFEK(gl)SLLMGK_
GPS1 Ubiquitylation K479 0.097 _SLLMGK(gl)EFQR_
GPS1 Ubiquitylation K502 -0.539 -1.230 _NQIHVK(gl)SPPREGSQGELTPANSQSR_
GPS1 Phosphorylation S503 -0.084 _NQIHVKS(ph)PPR_
GPS1 Phosphorylation S509 0.192 0.433 _EGS(ph)QGELTPANSQSR_
GPS1 Phosphorylation T514 0.479 0.814 _EGSQGELT(ph)PANS(ph)QSR_
GPS1 Phosphorylation S518 3.914 _EGSQGELT(ph)PANS(ph)QSR_
PPP2CA Ubiquitylation K4 -0.788 -0.378 _(ac)MDDK(gl)AFTK_
PPP2CA Ubiquitylation K4 -0.450 -0.016 _(ac)M(ox)DEK(gl)VFTK_
PPP2CA Ubiquitylation K8 -0.522 _VFTK(gl)ELDQWIEQLNECK_
PPP2CA Ubiquitylation K21 -1.370 _ELDQWVEQLNECK(gl)QLNENQVR_
PPP2CA Ubiquitylation K21 -1.106 _ELDQWIEQLNECK(gl)QLSESQVK_
PPP2CA Ubiquitylation K29 0.211 0.122 _QLSESQVK(gl)SLCEK_
PPP2CA Ubiquitylation K36 -0.455 0.187 _AK(gl)EILTK_
PPP2CA Ubiquitylation K36 -0.455 0.187 _AK(gl)EILTK_
PPP2CA Ubiquitylation K41 -0.049 0.003 _EILTK(gl)ESNVQEVR_
PPP2CA Ubiquitylation K74 -0.316 -0.316 _IGGK(gl)SPDTNYLFMGDYVDR_
PPP2R1A Ubiquitylation K34 0.304 _K(gl)LSTIALALGVER_
PPP2R1A Ubiquitylation K107 0.584 0.441 _DK(gl)AVESLR_
PPP2R1A Ubiquitylation K163 0.106 0.149 _VSSAVK(gl)AELR_
PPP2R1A Ubiquitylation K175 -0.351 _ASNAVK(gl)AEIR_
PPP2R1A Ubiquitylation K188 0.395 0.130 _AAASK(gl)LGEFAK_
PPP2R1A Ubiquitylation K255 0.301 0.202 _QAAEDK(gl)SWR_
PPP2R1A Ubiquitylation K266 0.464 0.338 _YMVADK(gl)FTELQK_
PPP2R1A Ubiquitylation K284 -0.575 _FSELQK(gl)AMGPK_
PPP2R1A Ubiquitylation K307 0.224 0.500 _VK(gl)EFCENLSADCR_
PPP2R1A Ubiquitylation K467 0.890 _EAATSNLK(gl)K_
PPP2R1A Ubiquitylation K468 0.890 _EAATSNLK(gl)K_
PPP2R1A Ubiquitylation K542 -0.187 _FNVAK(gl)SLQK_
PPP2R1B Ubiquitylation K175 -0.351 _ASNAVK(gl)AEIR_
PPP2R1B Ubiquitylation K284 -0.575 _FSELQK(gl)AMGPK_
PRKCA Phosphorylation S10 -0.650 0.036 _(ac)ADVFPGNDS(ph)TASQDVANR_
PRKCA Phosphorylation S13 -1.038 0.335 _(ac)ADVFPGNDSTAS(ph)QDVANR_
PRKCA Phosphorylation S226 0.693 0.415 _STLNPQWNES(ph)FTFK_
PRKCA Ubiquitylation K316 -0.522 -0.535 _LGPAGNK(gl)VISPSEDR_
RGS3 Phosphorylation S806 -0.235 0.091 _DLPAIQES(ph)PTR_
SPRED2 Ubiquitylation K254 -0.999 _GK(gl)YPDPSEDADSSYVR_


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