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Query: SPRED2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SPRED2 0 -0.999 0.990 -1.050

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SPRED2 Ubiquitylation K254 -0.999 _GK(gl)YPDPSEDADSSYVR_

Background Information for SPRED2:





Protein-protein Interactions for SPRED2

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SPRED2 Cat. description Hein, Mann, Cell 2015


Protein Domains in SPRED2

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Sprouty IPR007875 0.1
Category members WH1/EVH1 IPR000697 0


Protein complexes (CORUM database) featuring SPRED2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SPRED2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members Pathway Pathway_447 KEGG_JAK_STAT_SIGNALING_PATHWAY 0 0.13
Category members Pathway Pathway_522 PID_KIT_PATHWAY 0 0
Category members GO Category GO:0000188 inactivation of MAPK activity Database 0
Category members GO Category GO:0005173 stem cell factor receptor binding Database 0
Category members GO Category GO:0009966 regulation of signal transduction Database 0
Category members GO Category GO:0010801 negative regulation of peptidyl-threonine phosphorylation Database 0
Category members GO Category GO:0030291 protein serine/threonine kinase inhibitor activity Database 0
Category members GO Category GO:0030658 transport vesicle membrane Database 0
Category members GO Category GO:0031410 cytoplasmic vesicle Database 0
Category members GO Category GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator Database 0


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