bioLOGIC Category
Results for the Category
positive regulation of DNA damage response, signal transduction by p53 class mediator
(GO:0043517)
RNAi screen result
|
RNAPII IP (MG132) |
CSB IP |
CSB IP (MG132) |
Chrom. |
Chrom. (MG132) |
Ubi /Phospo |
Ubi /Phospho (MG132) |
W |
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
Gene name |
MGoogle Score |
RNAi high |
RNAi low |
RNAPII-IP (MG132) |
CSB-IP |
CSB-IP (MG132) |
Chrom. |
Chrom. (MG132) |
ATR
|
1
|
-1.040
|
0.920
|
0.671
|
|
|
1.041
|
0.708
|
EEF1E1
|
0
|
0.700
|
-0.120
|
0.177
|
|
|
0.427
|
0.615
|
PMAIP1
|
0
|
0.570
|
-0.670
|
|
|
|
|
|
CDKN2A
|
0
|
-0.080
|
-0.260
|
-0.556
|
|
-1.080
|
-3.270
|
-1.110
|
ATM
|
0
|
|
|
|
|
|
0.398
|
0.474
|
MSX1
|
0
|
0.420
|
-0.450
|
|
|
|
|
|
SPRED2
|
0
|
0.990
|
-1.050
|
|
|
|
|
|
Gene name |
PTM type |
PTM site |
UV |
UV (MG132) |
Sequence |
ATM
|
Ubiquitylation
|
K307
|
|
-0.196
|
_GAYESTK(gl)WR_
|
ATM
|
Ubiquitylation
|
K331
|
|
-0.126
|
_GK(gl)YSSGFR_
|
ATM
|
Ubiquitylation
|
K385
|
|
-0.669
|
_ESSDYSVPCK(gl)R_
|
ATM
|
Ubiquitylation
|
K1101
|
|
-0.548
|
_LFQDTK(gl)GDSSR_
|
ATM
|
Ubiquitylation
|
K1109
|
|
-1.666
|
_LLK(gl)ALPLK_
|
ATM
|
Ubiquitylation
|
K1698
|
|
-1.026
|
_DASYTK(gl)ALK_
|
ATM
|
Ubiquitylation
|
K1738
|
|
-0.137
|
_SAAVTCLK(gl)NILATK_
|
ATM
|
Ubiquitylation
|
K2025
|
|
-1.497
|
_SIGEPDSLYGCGGGK(gl)MLQPITR_
|
ATR
|
Ubiquitylation
|
K32
|
|
-0.929
|
_ELGSATPEEYNTVVQK(gl)PR_
|
ATR
|
Phosphorylation
|
S435
|
0.516
|
0.284
|
_RLS(ph)SSLNPSK_
|
ATR
|
Ubiquitylation
|
K746
|
|
-1.823
|
_NLK(gl)ATSQHECSSSQLK_
|
ATR
|
Ubiquitylation
|
K1019
|
1.662
|
|
_TLGK(gl)QLNVNRR_
|
ATR
|
Ubiquitylation
|
K1600
|
-0.437
|
|
_FQALK(gl)AEK_
|
ATR
|
Ubiquitylation
|
K2106
|
|
-0.136
|
_AYEWEK(gl)AGR_
|
ATR
|
Ubiquitylation
|
K2604
|
0.657
|
1.118
|
_LQGVIK(gl)TR_
|
EEF1E1
|
Ubiquitylation
|
K18
|
0.406
|
|
_SLGLSK(gl)GNK_
|
EEF1E1
|
Ubiquitylation
|
K21
|
|
-0.200
|
_SLGLSKGNK(gl)_
|
MSX1
|
Phosphorylation
|
S154
|
|
0.148
|
_RLS(ph)PPACTLR_
|
PMAIP1
|
Ubiquitylation
|
K35
|
-1.475
|
0.286
|
_RFGDK(gl)LNFR_
|
PMAIP1
|
Ubiquitylation
|
K41
|
-1.597
|
0.340
|
_QK(gl)LLNLISK_
|
PMAIP1
|
Ubiquitylation
|
K48
|
-2.007
|
-0.586
|
_LLNLISK(gl)_
|
SPRED2
|
Ubiquitylation
|
K254
|
-0.999
|
|
_GK(gl)YPDPSEDADSSYVR_
|
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