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Query: MSX1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MSX1 0 0.148 0.420 -0.450

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MSX1 Phosphorylation S154 0.148 _RLS(ph)PPACTLR_

Background Information for MSX1:


Pubmed-MSX1 »
Uniprot-MSX1 »
Biogrid-MSX1 »
ProteomicsDB-MSX1 »

Tumorportal-MSX1 »
COSMIC-MSX1 »
GenomeRNAi-MSX1 »
Genecards-MSX1


Protein-protein Interactions for MSX1
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in MSX1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Homeobox_dom IPR001356 0.63
Category members Homeobox_metazoa IPR020479 0.28
Category members Homeodomain-like IPR009057 0


Protein complexes (CORUM database) featuring MSX1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 684 PAX9-MSX1 complex Database 0


Categories featuring MSX1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0002039 p53 binding Database 2.06
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0001228 RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Database 0.27
Category members GO Category GO:0060021 palate development Database 0.23
Category members GO Category GO:0030509 BMP signaling pathway Database 0.2
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members GO Category GO:0005667 transcription factor complex Database 0.19
Category members GO Category GO:0030308 negative regulation of cell growth Database 0.18
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0060349 bone morphogenesis Database 0.17
Category members GO Category GO:0034504 protein localization to nucleus Database 0.15
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0042476 odontogenesis Database 0.09
Category members GO Category GO:0023019 signal transduction involved in regulation of gene expression Database 0.08
Category members GO Category GO:0035067 negative regulation of histone acetylation Database 0.08
Category members GO Category GO:0009952 anterior/posterior pattern specification Database 0.06
Category members GO Category GO:0030513 positive regulation of BMP signaling pathway Database 0.05
Category members GO Category GO:0050821 protein stabilization Database 0.04
Category members GO Category GO:0071316 cellular response to nicotine Database 0.03
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0043392 negative regulation of DNA binding Database 0.01
Category members Disease phenotype Cleft_Lip_+/-_Cleft_Palate Cleft Lip +/- Cleft Palate Database 0
Category members Disease phenotype Oligodontia Oligodontia Database 0
Category members GO Category GO:0000902 cell morphogenesis Database 0
Category members GO Category GO:0000982 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity Database 0
Category members GO Category GO:0001837 epithelial to mesenchymal transition Database 0
Category members GO Category GO:0003007 heart morphogenesis Database 0
Category members GO Category GO:0003198 epithelial to mesenchymal transition involved in endocardial cushion formation Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007507 heart development Database 0
Category members GO Category GO:0007517 muscle organ development Database 0
Category members GO Category GO:0010463 mesenchymal cell proliferation Database 0
Category members GO Category GO:0021983 pituitary gland development Database 0
Category members GO Category GO:0030262 apoptotic nuclear changes Database 0
Category members GO Category GO:0030326 embryonic limb morphogenesis Database 0
Category members GO Category GO:0030900 forebrain development Database 0
Category members GO Category GO:0030901 midbrain development Database 0
Category members GO Category GO:0035115 embryonic forelimb morphogenesis Database 0
Category members GO Category GO:0035116 embryonic hindlimb morphogenesis Database 0
Category members GO Category GO:0035880 embryonic nail plate morphogenesis Database 0
Category members GO Category GO:0042474 middle ear morphogenesis Database 0
Category members GO Category GO:0042475 odontogenesis of dentin-containing tooth Database 0
Category members GO Category GO:0042481 regulation of odontogenesis Database 0
Category members GO Category GO:0042733 embryonic digit morphogenesis Database 0
Category members GO Category GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator Database 0
Category members GO Category GO:0048863 stem cell differentiation Database 0
Category members GO Category GO:0051154 negative regulation of striated muscle cell differentiation Database 0
Category members GO Category GO:0051216 cartilage development Database 0
Category members GO Category GO:0060325 face morphogenesis Database 0
Category members GO Category GO:0060536 cartilage morphogenesis Database 0
Category members GO Category GO:0061180 mammary gland epithelium development Database 0
Category members GO Category GO:0061312 BMP signaling pathway involved in heart development Database 0


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