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Query: PMAIP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PMAIP1 0 -1.135 0.570 -0.670

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PMAIP1 Ubiquitylation K41 -1.597 0.340 _QK(gl)LLNLISK_
PMAIP1 Ubiquitylation K35 -1.475 0.286 _RFGDK(gl)LNFR_
PMAIP1 Ubiquitylation K48 -2.007 -0.586 _LLNLISK(gl)_

Background Information for PMAIP1:


Pubmed-PMAIP1 »
Uniprot-PMAIP1 »
Biogrid-PMAIP1 »
ProteomicsDB-PMAIP1 »

Tumorportal-PMAIP1 »
COSMIC-PMAIP1 »
GenomeRNAi-PMAIP1 »
Genecards-PMAIP1


Protein-protein Interactions for PMAIP1
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in PMAIP1
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring PMAIP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PMAIP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006974 cellular response to DNA damage stimulus Database 3.57
Category members Pathway Pathway_837 REACTOME_APOPTOSIS 0 2.39
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage Database 1.14
Category members Pathway Pathway_65 PID_MYC_ACTIV_PATHWAY 0 1.08
Category members GO Category GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator Database 0.83
Category members GO Category GO:0009411 response to UV Database 0.79
Category members Pathway Pathway_208 PID_TAP63_PATHWAY 0 0.52
Category members GO Category GO:0005741 mitochondrial outer membrane Database 0.46
Category members GO Category GO:0043331 response to dsRNA Database 0.34
Category members GO Category GO:0046902 regulation of mitochondrial membrane permeability Database 0.33
Category members GO Category GO:0010165 response to X-ray Database 0.32
Category members Pathway Pathway_382 KEGG_P53_SIGNALING_PATHWAY 0 0.26
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members Pathway Pathway_383 PID_P53_DOWNSTREAM_PATHWAY 0 0.23
Category members GO Category GO:0001836 release of cytochrome c from mitochondria Database 0.18
Category members GO Category GO:0010498 proteasomal protein catabolic process Database 0.1
Category members GO Category GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process Database 0.08
Category members GO Category GO:0010917 negative regulation of mitochondrial membrane potential Database 0.08
Category members GO Category GO:0051607 defense response to virus Database 0.07
Category members GO Category GO:0010907 positive regulation of glucose metabolic process Database 0.04
Category members Pathway Pathway_988 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS 0 0
Category members Pathway Pathway_990 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS 0 0
Category members GO Category GO:0032461 positive regulation of protein oligomerization Database 0
Category members GO Category GO:0042149 cellular response to glucose starvation Database 0
Category members GO Category GO:0043029 T cell homeostasis Database 0
Category members GO Category GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Database 0
Category members GO Category GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator Database 0
Category members GO Category GO:0043525 positive regulation of neuron apoptotic process Database 0
Category members GO Category GO:0048147 negative regulation of fibroblast proliferation Database 0
Category members GO Category GO:0071456 cellular response to hypoxia Database 0


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