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negative regulation of fibroblast proliferation
(GO:0048147)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
MORC3 2 -0.280 -0.100 0.309 0.499 0.162
SOD2 1 -0.340 0.140 2.161 -0.330
TRIM32 1 0.220 0.640 -1.832 -0.176 -1.091
CDC73 1 1.000 -0.660 1.109 0.620 1.610 -0.862 0.436
SKI 1 -1.870 2.800 -1.139 -0.588
FTH1 1 -0.230 0.610 2.863 0.755 1.309
FTH1 1 0.280 -0.310 2.863 0.755 1.309
GSTP1 0 -1.460 2.360 0.731 -2.952
BAX 0 1.590 -1.170 0.811 0.359
MYC 0 0.170 0.550 -2.443 -0.949 -0.454 -1.290
TP53 0 -1.070 1.050 -2.808 0.076 -0.094 0.436 0.497
PMAIP1 0 0.570 -0.670
DACH1 0
NF1 0 1.000 -0.500 0.444 -0.190

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
BAX Ubiquitylation K57 -1.174 _MGGEAPELALDPVPQDASTK(gl)K_
BAX Ubiquitylation K58 -1.718 -1.174 _MGGEAPELALDPVPQDASTKK(gl)_
BAX Ubiquitylation K64 0.708 1.306 _LSECLK(gl)R_
CDC73 Ubiquitylation K136 0.034 _AADEVLAEAK(gl)KPR_
CDC73 Ubiquitylation K161 1.275 _LEGHK(gl)EGIVQTEQIR_
CDC73 Ubiquitylation K198 0.681 _STIK(gl)TDLDDDITALK_
CDC73 Ubiquitylation K209 -0.003 -1.671 _TDLDDDITALK(gl)QR_
CDC73 Ubiquitylation K243 0.937 _TTILQSTGK(gl)NFSK_
CDC73 Ubiquitylation K247 0.739 _TTILQSTGKNFSK(gl)_
CDC73 Ubiquitylation K283 -0.189 _TK(gl)QPIPAAYNR_
DACH1 Ubiquitylation K713 -0.067 -0.579 _EQAEQTLK(gl)QAASTDSLR_
FTH1 Phosphorylation S228 0.272 _MGAPESGLAEYLFDKHTLGDS(ph)DNES_
MORC3 Phosphorylation S514 0.420 _HLS(ph)EGTNSYATR_
MORC3 Ubiquitylation K555 -1.251 _SSILNAK(gl)NRR_
MORC3 Phosphorylation S560 2.304 1.301 _RLS(ph)SQFENSVYK_
MORC3 Ubiquitylation K785 0.929 _K(gl)QCSALQHVK_
MORC3 Ubiquitylation K825 0.523 0.398 _QLDK(gl)CSIERDQYK_
MORC3 Ubiquitylation K844 0.024 _SEVELLEMEK(gl)SQIR_
MORC3 Ubiquitylation K855 1.663 _SQCEELK(gl)TEVEQLK_
MORC3 Ubiquitylation K891 0.406 _STNQQTATDVSTSSNIEESVNHMDGESLK(gl)LR_
MYC Phosphorylation S20 -1.444 -1.145 _PLNVS(ph)FTNR_
MYC Phosphorylation T72 -1.699 -1.813 _FELLPT(ph)PPLS(ph)PSRR_
MYC Phosphorylation S76 -1.777 -1.435 _FELLPTPPLS(ph)PSR_
MYC Phosphorylation S81 0.459 _S(ph)GLCSPSYVAVTPFSLR_
MYC Phosphorylation S85 0.199 0.073 _SGLCS(ph)PSYVAVTPFSLR_
MYC Ubiquitylation K162 -2.475 -1.259 _LVSEK(gl)LASYQAAR_
MYC Phosphorylation S295 -0.903 _SESGS(ph)PSAGGHSKPPHSPLVLK_
MYC Phosphorylation S307 -1.486 _SES(ph)GSPSAGGHSKPPHS(ph)PLVLK_
MYC Ubiquitylation K340 -2.449 _VK(gl)LDSVR_
MYC Ubiquitylation K403 -3.432 _DQIPELENNEK(gl)APK_
NF1 Ubiquitylation K471 0.218 _MAPSLTFKEK(gl)_
NF1 Phosphorylation S864 -0.458 _SNSGLATYS(ph)PPMGPVSER_
NF1 Phosphorylation T2514 0.076 _GSEGYLAATYPTVGQT(ph)SPR_
NF1 Phosphorylation S2515 0.071 0.316 _GSEGYLAATYPTVGQTS(ph)PR_
NF1 Phosphorylation S2543 0.698 0.655 _S(ph)FDHLISDTK_
PMAIP1 Ubiquitylation K35 -1.475 0.286 _RFGDK(gl)LNFR_
PMAIP1 Ubiquitylation K41 -1.597 0.340 _QK(gl)LLNLISK_
PMAIP1 Ubiquitylation K48 -2.007 -0.586 _LLNLISK(gl)_
SKI Ubiquitylation K294 -0.126 -0.054 _AYILLSQDYTGK(gl)EEQAR_
SKI Ubiquitylation K365 -0.244 -0.390 _TLAGSSNK(gl)SLGCVHPR_
SKI Phosphorylation S431 -0.475 _VVS(ph)SPPCAAAVSR_
SKI Phosphorylation S432 -0.742 -0.438 _VVSS(ph)PPCAAAVSR_
SKI Phosphorylation S480 -1.160 -1.491 _LTVDTPGAPETLAPVAAPEEDKDS(ph)EAEVEVESR_
TP53 Ubiquitylation K120 -0.188 _LGFLHSGTAK(gl)SVTCTYSPALNK_
TP53 Ubiquitylation K164 0.157 -1.260 _AMAIYK(gl)QSQHMTEVVR_
TP53 Phosphorylation S314 -0.695 -1.000 _ALPNNTSS(ph)SPQPK_
TP53 Phosphorylation S315 -0.762 -0.959 _RALPNNTSSS(ph)PQPK_
TP53 Ubiquitylation K320 -0.978 _ALPNNTSSSPQPKK(gl)_
TP53 Ubiquitylation K357 -0.231 -0.823 _ELNEALELKDAQAGK(gl)EPGGSR_
TRIM32 Ubiquitylation K175 0.333 -0.305 _AALEGVSK(gl)DLQAR_
TRIM32 Ubiquitylation K204 1.221 _K(gl)FFTGSLAEVEK_
TRIM32 Ubiquitylation K405 2.753 _GFLK(gl)EIRR_
TRIM32 Ubiquitylation K506 0.638 _GSGVVK(gl)YSCLCSAVRPK_


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