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Query: FTH1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FTH1 1 5.809 -0.230 0.610 2.863 0.755 1.309
FTH1 1 5.809 0.280 -0.310 2.863 0.755 1.309

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FTH1 Phosphorylation S228 0.272 _MGAPESGLAEYLFDKHTLGDS(ph)DNES_

Background Information for FTH1:





Protein-protein Interactions for FTH1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FTH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FTH1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ferritin_DPS_dom IPR008331 0
Category members Ferritin-like_diiron IPR009040 0
Category members Ferritin-like_SF IPR009078 0


Protein complexes (CORUM database) featuring FTH1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FTH1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0006955 immune response Database 1.22
Category members Pathway Pathway_474 REACTOME_MEMBRANE_TRAFFICKING 0 1.14
Category members Pathway Pathway_475 REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING 0 0.98
Category members Pathway Pathway_520 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS 0 0.78
Category members GO Category GO:0006892 post-Golgi vesicle-mediated transport Database 0.74
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0008043 intracellular ferritin complex Database 0.23
Category members Pathway Pathway_142 PID_MYC_REPRESS_PATHWAY 0 0.21
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members GO Category GO:0005506 iron ion binding Database 0.04
Category members Pathway Pathway_81 KEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM 0 0.01
Category members Pathway Pathway_193 REACTOME_IRON_UPTAKE_AND_TRANSPORT 0 0
Category members GO Category GO:0004322 ferroxidase activity Database 0
Category members GO Category GO:0006826 iron ion transport Database 0
Category members GO Category GO:0006879 cellular iron ion homeostasis Database 0
Category members GO Category GO:0006880 intracellular sequestering of iron ion Database 0
Category members GO Category GO:0008199 ferric iron binding Database 0
Category members GO Category GO:0048147 negative regulation of fibroblast proliferation Database 0


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