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Query: GSTP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GSTP1 0 2.926 -1.460 2.360 -0.165
GSTP1 0 2.926 -1.460 2.360 0.731 -2.952

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for GSTP1:


Pubmed-GSTP1 »
Uniprot-GSTP1 »
Biogrid-GSTP1 »
ProteomicsDB-GSTP1 »

Tumorportal-GSTP1 »
COSMIC-GSTP1 »
GenomeRNAi-GSTP1 »
Genecards-GSTP1


Protein-protein Interactions for GSTP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GSTP1 Cat. description Hein, Mann, Cell 2015


Protein Domains in GSTP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Glutathione-S-Trfase_C-like IPR010987 0.23
Category members Thioredoxin-like_fold IPR012336 0.16
Category members Glutathione_S-Trfase_N IPR004045 0
Category members GST_C IPR004046 0


Protein complexes (CORUM database) featuring GSTP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GSTP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0043409 negative regulation of MAPK cascade Database 0.87
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0000302 response to reactive oxygen species Database 0.35
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0032930 positive regulation of superoxide anion generation Database 0.27
Category members Pathway Pathway_177 KEGG_PROSTATE_CANCER 0 0.13
Category members GO Category GO:0032872 regulation of stress-activated MAPK cascade Database 0.11
Category members GO Category GO:0070373 negative regulation of ERK1 and ERK2 cascade Database 0.1
Category members Pathway Pathway_72 KEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450 0 0.04
Category members Pathway Pathway_24 KEGG_PATHWAYS_IN_CANCER 0 0
Category members Pathway Pathway_27 KEGG_GLUTATHIONE_METABOLISM 0 0
Category members Pathway Pathway_452 REACTOME_GLUTATHIONE_CONJUGATION 0 0
Category members Pathway Pathway_82 REACTOME_PHASE_II_CONJUGATION 0 0
Category members Pathway Pathway_85 REACTOME_BIOLOGICAL_OXIDATIONS 0 0
Category members Pathway Pathway_86 KEGG_DRUG_METABOLISM_CYTOCHROME_P450 0 0
Category members GO Category GO:0002674 negative regulation of acute inflammatory response Database 0
Category members GO Category GO:0004364 glutathione transferase activity Database 0
Category members GO Category GO:0006469 negative regulation of protein kinase activity Database 0
Category members GO Category GO:0006749 glutathione metabolic process Database 0
Category members GO Category GO:0006805 xenobiotic metabolic process Database 0
Category members GO Category GO:0007417 central nervous system development Database 0
Category members GO Category GO:0008432 JUN kinase binding Database 0
Category members GO Category GO:0009890 negative regulation of biosynthetic process Database 0
Category members GO Category GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway Database 0
Category members GO Category GO:0019207 kinase regulator activity Database 0
Category members GO Category GO:0032691 negative regulation of interleukin-1 beta production Database 0
Category members GO Category GO:0032720 negative regulation of tumor necrosis factor production Database 0
Category members GO Category GO:0032873 negative regulation of stress-activated MAPK cascade Database 0
Category members GO Category GO:0035726 common myeloid progenitor cell proliferation Database 0
Category members GO Category GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling Database 0
Category members GO Category GO:0043407 negative regulation of MAP kinase activity Database 0
Category members GO Category GO:0043508 negative regulation of JUN kinase activity Database 0
Category members GO Category GO:0048147 negative regulation of fibroblast proliferation Database 0
Category members GO Category GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process Database 0
Category members GO Category GO:0060547 negative regulation of necrotic cell death Database 0
Category members GO Category GO:0070372 regulation of ERK1 and ERK2 cascade Database 0
Category members GO Category GO:0071222 cellular response to lipopolysaccharide Database 0


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