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KEGG_GLUTATHIONE_METABOLISM
(Pathway_27)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
LAP3 1 1.320 -0.850 0.723 1.542 1.333
RRM2B 1 -0.160 -0.120
ODC1 1 -0.780 0.940
SRM 1 1.420 -1.060 0.631 1.832 0.593
IDH1 1 0.390 -0.320 1.581 0.783
RRM1 1 0.717 1.039 0.509
RRM2 1
IDH2 1 0.090 -0.520 0.923 -2.210 2.164 1.203
GGCT 0 -0.960 0.880 -3.956
MGST1 0 -0.160 0.420 -0.611
GCLM 0 0.680 -0.230
GSTP1 0 -1.460 2.360 0.731 -2.952
MGST2 0 -0.730 0.630 -0.876 -0.918
GSS 0 0.500 -0.550
GSR 0 -0.310 0.020 -0.452 -1.012 0.319 0.351
TXNDC12 0 0.530 -0.510 -0.710
GGT7 0 1.140 -0.250 0.619 0.867
GSTM3 0 -0.400 0.800
PGD 0 0.730 0.030 0.129 -0.117 0.435
MGST3 0 0.380 0.250 0.082 0.759
GSTO1 0 0.140 -0.070 0.418 1.079
GSTO1 0 0.140 -0.070 -0.859
GSTK1 0 0.050 -0.370 -0.002 0.473 0.634

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
GCLM Ubiquitylation K90 -0.531 -0.229 _INPDEREEMK(gl)VSAK_
GGCT Ubiquitylation K118 0.583 1.156 _VATQEGK(gl)EITCR_
GGCT Ubiquitylation K140 -0.793 _SYLMTNYESAPPSPQYK(gl)K_
GGCT Ubiquitylation K141 -0.924 -0.793 _SYLM(ox)TNYESAPPSPQYKK(gl)_
GGT7 Phosphorylation S72 1.369 -0.055 _LPS(ph)SSSEMGSQDGSPLR_
GGT7 Phosphorylation S73 1.007 0.332 _LPSS(ph)SSEMGSQDGSPLR_
GSR Ubiquitylation K296 0.979 _FSQVK(gl)EVKK_
GSR Ubiquitylation K340 0.183 -0.002 _VPNTK(gl)DLSLNK_
GSS Ubiquitylation K186 -1.617 _ILSNNPSK(gl)GLALGIAK_
GSS Ubiquitylation K364 -0.926 _FVLK(gl)PQR_
GSS Phosphorylation S415 0.209 0.387 _IEPEPFENCLLRPGS(ph)PAR_
GSTM3 Ubiquitylation K79 -0.485 _NK(gl)ITQSNAILR_
GSTO1 Ubiquitylation K11 -2.209 -1.715 _SLGK(gl)GSAPPGPVPEGSIR_
GSTO1 Ubiquitylation K66 -0.290 _NKPEWFFKK(gl)_
GSTO1 Ubiquitylation K188 -0.206 _LEAMK(gl)LNECVDHTPK_
IDH1 Ubiquitylation K58 -0.442 0.097 _DATNDQVTK(gl)DAAEAIKK_
MGST2 Ubiquitylation K34 -0.986 _YK(gl)VTPPAVTGSPEFER_
ODC1 Ubiquitylation K57 1.669 _WLK(gl)ALPR_
ODC1 Ubiquitylation K115 0.685 _IIYANPCK(gl)QVSQIK_
ODC1 Ubiquitylation K161 1.311 _IATDDSK(gl)AVCR_
PGD Ubiquitylation K48 0.157 0.330 _VDDFLANEAK(gl)GTK_
PGD Ubiquitylation K51 -0.548 -0.001 _GTK(gl)VVGAQSLK_
PGD Ubiquitylation K59 0.785 1.117 _VVGAQSLK(gl)EMVSK_
RRM1 Ubiquitylation K158 0.366 0.759 _SYLLK(gl)INGK_
RRM1 Ubiquitylation K376 0.409 0.370 _LYASYEK(gl)QGR_
RRM1 Ubiquitylation K414 0.015 _K(gl)SNQQNLGTIK_
RRM1 Ubiquitylation K465 -0.049 0.272 _K(gl)LAEVTK_
RRM1 Ubiquitylation K471 1.117 1.347 _LAEVTK(gl)VVVR_
RRM1 Ubiquitylation K496 0.699 1.559 _IIDINYYPVPEACLSNK(gl)R_
RRM1 Ubiquitylation K587 0.487 _VLKEK(gl)IAK_
RRM1 Ubiquitylation K590 -0.395 0.551 _IAK(gl)YGIR_
RRM1 Ubiquitylation K689 0.606 _TVWEISQK(gl)TVLK_
RRM1 Ubiquitylation K693 0.427 _TVLK(gl)MAAER_
RRM1 Ubiquitylation K733 0.748 _QGLK(gl)TGMYYLR_
RRM1 Ubiquitylation K754 -0.746 -1.217 _TRPAANPIQFTLNK(gl)EK_
RRM1 Ubiquitylation K756 -0.746 -1.217 _TRPAANPIQFTLNK(gl)EK_
RRM2 Phosphorylation S80 -1.483 -1.780 _VPLAPITDPQQLQLS(ph)PLK_
RRM2 Phosphorylation T93 -1.284 -0.534 _GLSLVDKENT(ph)PPALSGTR_
RRM2 Ubiquitylation K106 -0.247 _VLASK(gl)TAR_
RRM2 Ubiquitylation K121 -2.427 -0.884 _TK(gl)AAAPGVEDEPLLR_
RRM2 Ubiquitylation K424 2.394 -0.588 _TNFFEK(gl)R_
RRM2B Ubiquitylation K424 2.394 -0.588 _TNFFEK(gl)R_


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