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Query: GSTO1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GSTO1 0 -1.282 0.140 -0.070 0.418 1.079
GSTO1 0 -1.282 0.140 -0.070 -0.859

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GSTO1 Ubiquitylation K11 -2.209 -1.715 _SLGK(gl)GSAPPGPVPEGSIR_
GSTO1 Ubiquitylation K66 -0.290 _NKPEWFFKK(gl)_
GSTO1 Ubiquitylation K188 -0.206 _LEAMK(gl)LNECVDHTPK_

Background Information for GSTO1:


Pubmed-GSTO1 »
Uniprot-GSTO1 »
Biogrid-GSTO1 »
ProteomicsDB-GSTO1 »

Tumorportal-GSTO1 »
COSMIC-GSTO1 »
GenomeRNAi-GSTO1 »
Genecards-GSTO1


Protein-protein Interactions for GSTO1
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in GSTO1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Glutathione-S-Trfase_C-like IPR010987 0.23
Category members Thioredoxin-like_fold IPR012336 0.16
Category members Glutathione_S-Trfase_N IPR004045 0
Category members GST_C IPR004046 0


Protein complexes (CORUM database) featuring GSTO1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GSTO1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity Database 0.33
Category members GO Category GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity Database 0.19
Category members Pathway Pathway_279 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS 0 0.18
Category members GO Category GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum Database 0.12
Category members GO Category GO:0019852 L-ascorbic acid metabolic process Database 0.04
Category members Pathway Pathway_72 KEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450 0 0.04
Category members Pathway Pathway_27 KEGG_GLUTATHIONE_METABOLISM 0 0
Category members Pathway Pathway_452 REACTOME_GLUTATHIONE_CONJUGATION 0 0
Category members Pathway Pathway_82 REACTOME_PHASE_II_CONJUGATION 0 0
Category members Pathway Pathway_85 REACTOME_BIOLOGICAL_OXIDATIONS 0 0
Category members Pathway Pathway_86 KEGG_DRUG_METABOLISM_CYTOCHROME_P450 0 0
Category members GO Category GO:0004364 glutathione transferase activity Database 0
Category members GO Category GO:0006805 xenobiotic metabolic process Database 0
Category members GO Category GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion Database 0
Category members GO Category GO:0016491 oxidoreductase activity Database 0
Category members GO Category GO:0042178 xenobiotic catabolic process Database 0
Category members GO Category GO:0071243 cellular response to arsenic-containing substance Database 0


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