Results for the Category
regulation of ERK1 and ERK2 cascade
(GO:0070372)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| EPHA7 | 2 | 2.050 | -0.990 | 0.221 | ||||
| EPHA7 | 2 | 2.050 | -0.990 | |||||
| LYN | 1 | -1.790 | 3.770 | |||||
| LYN | 1 | -1.790 | 3.770 | |||||
| GSTP1 | 0 | -1.460 | 2.360 | 0.731 | -2.952 | |||
| ERBB2 | 0 | -1.310 | 1.360 | |||||
| EPHA2 | 0 | 1.330 | -0.460 | 0.221 | ||||
| APIP | 0 | -0.210 | -0.260 | |||||
| APIP | 0 | 1.370 | -0.480 | |||||
| EPHB1 | 0 | -0.220 | 0.000 | 0.221 | ||||
| EPHB1 | 0 | -0.220 | 0.000 | -0.042 | ||||
| EPHB1 | 0 | -0.220 | 0.000 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| APIP | Phosphorylation | S104 | -0.232 | -0.421 | _DISGPS(ph)PSK_ |
| EPHA2 | Ubiquitylation | K578 | -0.752 | -0.618 | _QSPEDVYFSK(gl)SEQLKPLK_ |
| EPHA2 | Ubiquitylation | K583 | 0.445 | 0.124 | _SEQLK(gl)PLK_ |
| EPHA2 | Ubiquitylation | K617 | 0.339 | _QK(gl)VIGAGEFGEVYK_ | |
| EPHA2 | Ubiquitylation | K649 | -1.219 | _TLK(gl)AGYTEK_ | |
| EPHA2 | Phosphorylation | S897 | 0.000 | _LPS(ph)TSGSEGVPFR_ | |
| EPHA2 | Phosphorylation | T898 | -0.329 | 0.424 | _LPST(ph)SGSEGVPFR_ |
| EPHA7 | Ubiquitylation | K180 | 0.633 | _EIGPLSKK(gl)_ | |
| EPHA7 | Ubiquitylation | K272 | 0.520 | _AGYQQK(gl)GDTCEPCGR_ | |
| EPHA7 | Ubiquitylation | K578 | -0.752 | -0.618 | _QSPEDVYFSK(gl)SEQLKPLK_ |
| EPHA7 | Ubiquitylation | K583 | 0.445 | 0.124 | _SEQLK(gl)PLK_ |
| EPHA7 | Ubiquitylation | K606 | -0.162 | _FPGTK(gl)TYIDPETYEDPNR_ | |
| EPHA7 | Ubiquitylation | K617 | 0.339 | _QK(gl)VIGAGEFGEVYK_ | |
| EPHA7 | Ubiquitylation | K634 | 0.732 | 1.340 | _ELDASCIK(gl)IER_ |
| EPHA7 | Ubiquitylation | K649 | -1.219 | _TLK(gl)AGYTEK_ | |
| EPHA7 | Ubiquitylation | K657 | 0.533 | _LKLPGK(gl)R_ | |
| EPHA7 | Ubiquitylation | K665 | 3.196 | _DVAVAIK(gl)TLK_ | |
| EPHA7 | Ubiquitylation | K797 | -1.229 | -0.459 | _VIEDDPEAVYTTTGGK(gl)IPVR_ |
| EPHA7 | Phosphorylation | S897 | 0.000 | _LPS(ph)TSGSEGVPFR_ | |
| EPHA7 | Phosphorylation | T898 | -0.329 | 0.424 | _LPST(ph)SGSEGVPFR_ |
| EPHA7 | Phosphorylation | S912 | -0.413 | _TPLGTCSRPIS(ph)PLLDQNTPDFTTFCSVGEWLQAIK_ | |
| EPHB1 | Ubiquitylation | K578 | -0.752 | -0.618 | _QSPEDVYFSK(gl)SEQLKPLK_ |
| EPHB1 | Ubiquitylation | K583 | 0.445 | 0.124 | _SEQLK(gl)PLK_ |
| EPHB1 | Ubiquitylation | K617 | 0.339 | _QK(gl)VIGAGEFGEVYK_ | |
| EPHB1 | Ubiquitylation | K649 | -1.219 | _TLK(gl)AGYTEK_ | |
| EPHB1 | Ubiquitylation | K657 | 0.533 | _LKLPGK(gl)R_ | |
| EPHB1 | Phosphorylation | S897 | 0.000 | _LPS(ph)TSGSEGVPFR_ | |
| EPHB1 | Phosphorylation | T898 | -0.329 | 0.424 | _LPST(ph)SGSEGVPFR_ |
| ERBB2 | Ubiquitylation | K200 | -2.073 | _ACHPCSPMCK(gl)GSR_ | |
| ERBB2 | Ubiquitylation | K369 | -0.742 | _AVTSANIQEFAGCKK(gl)_ | |
| ERBB2 | Ubiquitylation | K747 | -0.505 | -0.019 | _GIWIPDGENVK(gl)IPVAIK_ |
| ERBB2 | Ubiquitylation | K854 | -0.859 | _NVLVK(gl)SPNHVK_ | |
| ERBB2 | Phosphorylation | S1054 | -0.476 | -0.706 | _S(ph)GGGDLTLGLEPSEEEAPR_ |
| LYN | Ubiquitylation | K20 | -0.592 | _GKDSLSDDGVDLK(gl)TQPVR_ | |
| LYN | Ubiquitylation | K40 | 0.100 | _DPTSNK(gl)QQRPVPESQLLPGQR_ | |
| LYN | Phosphorylation | S104 | 0.944 | 0.841 | _DSLS(ph)DDGVDLK_ |
| LYN | Ubiquitylation | K213 | 0.441 | _HYQK(gl)QADGLCR_ | |
| LYN | Ubiquitylation | K477 | -0.191 | _VENCPDELYDIMK(gl)MCWK_ |
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