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Query: EPHA7

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EPHA7 2 4.245 2.050 -0.990
EPHA7 2 4.245 2.050 -0.990 0.221

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EPHA7 Ubiquitylation K665 3.196 _DVAVAIK(gl)TLK_
EPHA7 Ubiquitylation K634 0.732 1.340 _ELDASCIK(gl)IER_
EPHA7 Ubiquitylation K180 0.633 _EIGPLSKK(gl)_
EPHA7 Ubiquitylation K272 0.520 _AGYQQK(gl)GDTCEPCGR_
EPHA7 Phosphorylation T898 -0.329 0.424 _LPST(ph)SGSEGVPFR_
EPHA7 Ubiquitylation K583 0.445 0.124 _SEQLK(gl)PLK_
EPHA7 Phosphorylation S897 0.000 _LPS(ph)TSGSEGVPFR_
EPHA7 Phosphorylation S912 -0.413 _TPLGTCSRPIS(ph)PLLDQNTPDFTTFCSVGEWLQAIK_
EPHA7 Ubiquitylation K797 -1.229 -0.459 _VIEDDPEAVYTTTGGK(gl)IPVR_
EPHA7 Ubiquitylation K578 -0.752 -0.618 _QSPEDVYFSK(gl)SEQLKPLK_
EPHA7 Ubiquitylation K617 0.339 _QK(gl)VIGAGEFGEVYK_
EPHA7 Ubiquitylation K649 -1.219 _TLK(gl)AGYTEK_
EPHA7 Ubiquitylation K606 -0.162 _FPGTK(gl)TYIDPETYEDPNR_
EPHA7 Ubiquitylation K657 0.533 _LKLPGK(gl)R_

Background Information for EPHA7:


Pubmed-EPHA7 »
Uniprot-EPHA7 »
Biogrid-EPHA7 »
ProteomicsDB-EPHA7 »

Tumorportal-EPHA7 »
COSMIC-EPHA7 »
GenomeRNAi-EPHA7 »
Genecards-EPHA7


Protein-protein Interactions for EPHA7
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CACNG2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPHA7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL17RB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL17RC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRIQ1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MANSC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MBLAC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRAP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PICK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAET1E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM30B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMPRSS11B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EPHA7
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Fibronectin_type3 IPR003961 0.19
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ephrin_rcpt_lig-bd_dom IPR001090 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members SAM IPR001660 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Galactose-bd-like IPR008979 0
Category members Growth_fac_rcpt_N_dom IPR009030 0
Category members SAM_2 IPR011510 0
Category members Tyr-kin_ephrin_A/B_rcpt-like IPR011641 0
Category members SAM/pointed IPR013761 0
Category members Tyr_kinase_ephrin_rcpt IPR016257 0
Category members Tyr_kinase_cat_dom IPR020635 0
Category members SAM_type1 IPR021129 0


Protein complexes (CORUM database) featuring EPHA7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring EPHA7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0031952 regulation of protein autophosphorylation Database 0.39
Category members GO Category GO:0046875 ephrin receptor binding Database 0.3
Category members GO Category GO:0030425 dendrite Database 0.26
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0016310 phosphorylation Database 0.21
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0045211 postsynaptic membrane Database 0.06
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members Pathway Pathway_1034 KEGG_AXON_GUIDANCE 0 0.04
Category members GO Category GO:0005004 GPI-linked ephrin receptor activity Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members Pathway Pathway_665 PID_EPHA_FWDPATHWAY 0 0.01
Category members GO Category GO:0005003 ephrin receptor activity Database 0
Category members GO Category GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway Database 0
Category members GO Category GO:0007420 brain development Database 0
Category members GO Category GO:0008046 axon guidance receptor activity Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0018108 peptidyl-tyrosine phosphorylation Database 0
Category members GO Category GO:0022407 regulation of cell-cell adhesion Database 0
Category members GO Category GO:0031290 retinal ganglion cell axon guidance Database 0
Category members GO Category GO:0031594 neuromuscular junction Database 0
Category members GO Category GO:0043025 neuronal cell body Database 0
Category members GO Category GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process Database 0
Category members GO Category GO:0043525 positive regulation of neuron apoptotic process Database 0
Category members GO Category GO:0045499 chemorepellent activity Database 0
Category members GO Category GO:0048013 ephrin receptor signaling pathway Database 0
Category members GO Category GO:0048755 branching morphogenesis of a nerve Database 0
Category members GO Category GO:0050730 regulation of peptidyl-tyrosine phosphorylation Database 0
Category members GO Category GO:0050919 negative chemotaxis Database 0
Category members GO Category GO:0070372 regulation of ERK1 and ERK2 cascade Database 0


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