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Query: TRIM32

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TRIM32 1 1.515 0.220 0.640 -1.832 -0.176 -1.091

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TRIM32 Ubiquitylation K204 1.221 _K(gl)FFTGSLAEVEK_
TRIM32 Ubiquitylation K175 0.333 -0.305 _AALEGVSK(gl)DLQAR_
TRIM32 Ubiquitylation K405 2.753 _GFLK(gl)EIRR_
TRIM32 Ubiquitylation K506 0.638 _GSGVVK(gl)YSCLCSAVRPK_

Background Information for TRIM32:


Pubmed-TRIM32 »
Uniprot-TRIM32 »
Biogrid-TRIM32 »
ProteomicsDB-TRIM32 »

Tumorportal-TRIM32 »
COSMIC-TRIM32 »
GenomeRNAi-TRIM32 »
Genecards-TRIM32


Protein-protein Interactions for TRIM32
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DNAJC7 Cat. description Hein, Mann, Cell 2015
Category members IP bait TRIM32 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA1C Cat. description Hein, Mann, Cell 2015
Category members IP bait 6-Sep Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ABI2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AKTIP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CRYL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DTNBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EXOC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM189B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NGB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait P4HA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SRPRB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TKT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TULP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TRIM32
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_B-box IPR000315 0
Category members NHL_repeat IPR001258 0
Category members Znf_RING IPR001841 0
Category members NHL_repeat_subgr IPR013017 0
Category members Znf_C3HC4_RING-type IPR018957 0


Protein complexes (CORUM database) featuring TRIM32
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TRIM32
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_764 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 0 2.56
Category members GO Category GO:0000209 protein polyubiquitination Database 2.46
Category members Pathway Pathway_888 KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS 0 2.22
Category members Pathway Pathway_832 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION 0 1.58
Category members GO Category GO:0043130 ubiquitin binding Database 1.22
Category members GO Category GO:0009411 response to UV Database 0.79
Category members GO Category GO:0030957 Tat protein binding Database 0.73
Category members GO Category GO:0032481 positive regulation of type I interferon production Database 0.54
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process Database 0.27
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0034612 response to tumor necrosis factor Database 0.21
Category members GO Category GO:0031369 translation initiation factor binding Database 0.1
Category members GO Category GO:0043621 protein self-association Database 0.07
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members GO Category GO:0050769 positive regulation of neurogenesis Database 0.06
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members GO Category GO:0045787 positive regulation of cell cycle Database 0.04
Category members GO Category GO:0032479 regulation of type I interferon production Database 0.04
Category members Disease phenotype BARDET-BIEDL_SYNDROME BARDET-BIEDL SYNDROME Database 0
Category members GO Category GO:0005863 striated muscle myosin thick filament Database 0
Category members GO Category GO:0017022 myosin binding Database 0
Category members GO Category GO:0030307 positive regulation of cell growth Database 0
Category members GO Category GO:0030335 positive regulation of cell migration Database 0
Category members GO Category GO:0045444 fat cell differentiation Database 0
Category members GO Category GO:0045666 positive regulation of neuron differentiation Database 0
Category members GO Category GO:0045732 positive regulation of protein catabolic process Database 0
Category members GO Category GO:0045862 positive regulation of proteolysis Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0048147 negative regulation of fibroblast proliferation Database 0
Category members GO Category GO:0051092 positive regulation of NF-kappaB transcription factor activity Database 0


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