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positive regulation of protein catabolic process
(GO:0045732)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
GSK3B 2 1.020 -0.870 -1.128 1.091
GSK3A 2 -1.420 1.510 -1.128 1.091
GSK3A 2 -1.420 1.510
CUL4B 2 1.400 -0.970 0.667 2.694 2.782 0.664 0.727
VCP 2 1.650 -0.640 -0.182 0.578 -0.596 0.007 -0.036
ITCH 1 1.000 -0.610 -0.346 0.023 0.613
TRIM32 1 0.220 0.640 -1.832 -0.176 -1.091
GGA3 1 1.320 -0.820
GGA3 1 1.320 -0.820
NDFIP1 1 2.140 -1.140
SNX1 0 -0.090 -0.590
NEDD4L 0 -0.050 -0.110
NEDD4 0 -1.320 1.730
ZNF268 0 1.050 -0.230
GGA1 0 1.030 -0.880
SGSM3 0 0.600 -0.480
CSNK2A1 0 0.050 -0.020 0.030 -0.550 1.362 0.022 -0.045
FZR1 0 0.740 -0.470
WNT5A 0
TNFAIP3 0 0.760 -0.500
BARD1 0 0.470 0.260
GJA1 0 -0.410 0.430
LPCAT1 0 0.790 -0.740 0.844 0.107 0.289

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
BARD1 Phosphorylation S186 0.193 0.942 _DASAQQDSYEFVSPS(ph)PPADVSER_
CSNK2A1 Ubiquitylation K71 0.008 _ILK(gl)PVKK_
CSNK2A1 Ubiquitylation K329 -0.661 -0.889 _EAMEHPYFYTVVK(gl)DQAR_
CUL4B Phosphorylation T49 0.078 0.263 _SATDGNTSTT(ph)PPTSAK_
CUL4B Phosphorylation T52 -1.359 _SATDGNTSTT(ph)PPT(ph)SAK_
CUL4B Phosphorylation S53 -0.213 _SATDGNTSTT(ph)PPTS(ph)AK_
CUL4B Phosphorylation S146 0.762 _MAEESSSSSSSSS(ph)PTAATSQQQQLK_
CUL4B Ubiquitylation K258 0.200 _ISANLYK(gl)QLR_
CUL4B Ubiquitylation K341 0.655 _AHIISDQK(gl)VQNK_
CUL4B Ubiquitylation K403 1.248 0.711 _LYAAEGQK(gl)LMQER_
CUL4B Ubiquitylation K609 0.798 _DVFEAFYKK(gl)_
CUL4B Ubiquitylation K789 -0.602 0.356 _TLQSLACGK(gl)AR_
FZR1 Ubiquitylation K135 -0.177 _GLFTYSLSTK(gl)R_
FZR1 Ubiquitylation K263 0.187 _GFVQIWDAAAGKK(gl)_
GGA1 Ubiquitylation K118 -1.027 0.051 _VVSPK(gl)YLGSR_
GGA1 Ubiquitylation K191 -0.968 _NVIFEDEEK(gl)SK_
GGA1 Ubiquitylation K193 -0.968 _NVIFEDEEK(gl)SK_
GGA1 Ubiquitylation K200 -0.112 -0.638 _LLK(gl)SSHPEDLR_
GGA1 Ubiquitylation K215 -1.131 -0.524 _LIK(gl)EMVQEDQKR_
GGA1 Ubiquitylation K223 -0.190 0.412 _EMVQEDQK(gl)R_
GGA3 Ubiquitylation K100 -0.181 -0.013 _VVSPK(gl)YLGDR_
GGA3 Phosphorylation S159 -1.676 -1.492 _TLIPS(ph)PPPRPK_
GGA3 Ubiquitylation K176 -0.101 _NPVFDDEEKSK(gl)LLAK_
GGA3 Ubiquitylation K180 -0.258 0.226 _LLAK(gl)LLK_
GGA3 Ubiquitylation K185 -0.073 -0.327 _SK(gl)NPDDLQEANK_
GGA3 Ubiquitylation K195 0.623 -0.266 _SKNPDDLQEANK(gl)LIK_
GGA3 Ubiquitylation K198 -0.091 0.421 _LIK(gl)SMVKEDEAR_
GGA3 Ubiquitylation K202 0.681 2.639 _SMVK(gl)EDEAR_
GGA3 Phosphorylation S425 -0.079 _EQS(ph)DLDFFSPR_
GJA1 Ubiquitylation K109 0.099 _LNKK(gl)EEELK_
GJA1 Ubiquitylation K128 0.209 1.057 _VAQTDGVNVDMHLK(gl)QIEIK_
GJA1 Ubiquitylation K136 -0.888 _FK(gl)YGIEEHGK_
GJA1 Ubiquitylation K243 0.152 0.237 _GK(gl)SDPYHATSGALSPAK_
GJA1 Ubiquitylation K258 -0.280 0.063 _SDPYHATSGALSPAK(gl)DCGSQK_
GJA1 Ubiquitylation K303 -0.106 0.280 _NYNK(gl)QASEQNWANYSAEQNR_
GJA1 Ubiquitylation K345 -0.464 _MGQAGSTISNSHAQPFDFPDDNQNSK(gl)K_
GJA1 Ubiquitylation K346 -1.004 -0.300 _MGQAGSTISNSHAQPFDFPDDNQNSKK(gl)_
GJA1 Phosphorylation S364 -0.300 _LAAGHELQPLAIVDQRPS(ph)SR_
GJA1 Phosphorylation S365 -0.300 _LAAGHELQPLAIVDQRPS(ph)SR_
GJA1 Phosphorylation S372 0.940 1.430 _AS(ph)SRPRPDDLEI_
GJA1 Phosphorylation S373 0.664 0.467 _ASS(ph)RPRPDDLEI_
GSK3A Phosphorylation S9 -0.483 0.010 _TTS(ph)FAESCKPVQQPSAFGSMK_
GSK3A Phosphorylation S21 -0.406 _TSS(ph)FAEPGGGGGGGGGGPGGSASGPGGTGGGK_
GSK3A Ubiquitylation K85 -0.204 _LCDSGELVAIK(gl)K_
GSK3A Ubiquitylation K86 -0.204 _LCDSGELVAIK(gl)K_
GSK3A Ubiquitylation K148 0.396 _ELVAIK(gl)K_
GSK3A Phosphorylation S215 0.296 0.477 _GEPNVS(ph)YICSR_
GSK3A Phosphorylation Y216 0.356 0.376 _GEPNVSY(ph)ICSR_
GSK3A Phosphorylation T390 2.800 2.527 _IQAAAST(ph)PTNATAASDANTGDR_
GSK3B Phosphorylation S9 -0.483 0.010 _TTS(ph)FAESCKPVQQPSAFGSMK_
GSK3B Ubiquitylation K85 -0.204 _LCDSGELVAIK(gl)K_
GSK3B Ubiquitylation K86 -0.204 _LCDSGELVAIK(gl)K_
GSK3B Phosphorylation S215 0.296 0.477 _GEPNVS(ph)YICSR_
GSK3B Phosphorylation Y216 0.356 0.376 _GEPNVSY(ph)ICSR_
GSK3B Phosphorylation T390 2.800 2.527 _IQAAAST(ph)PTNATAASDANTGDR_
ITCH Ubiquitylation K66 -0.890 _WK(gl)QPLTVIVTPVSK_
ITCH Ubiquitylation K350 0.049 0.396 _VYYVDHVEK(gl)R_
ITCH Ubiquitylation K446 -1.514 -1.539 _EFDPLGPLPPGWEK(gl)R_
ITCH Ubiquitylation K478 -1.265 _SQGQLNEK(gl)PLPEGWEMR_
ITCH Ubiquitylation K513 -0.564 1.593 _TGK(gl)SALDNGPQIAYVR_
ITCH Ubiquitylation K861 -0.810 0.596 _VGK(gl)ENWLPR_
LPCAT1 Ubiquitylation K191 -1.958 -0.654 _TVEEIK(gl)R_
LPCAT1 Ubiquitylation K221 -2.397 _TCLITFK(gl)PGAFIPGAPVQPVVLR_
LPCAT1 Ubiquitylation K347 -0.307 _GLGLKPEK(gl)_
NDFIP1 Ubiquitylation K83 -1.563 -0.959 _TK(gl)AEATIPLVPGRDEDFVGR_
NDFIP1 Ubiquitylation K204 -0.511 _K(gl)MPETFSNLPR_
NEDD4 Phosphorylation Y751 -0.924 _RGSLQAY(ph)TFEEQPTLPVLLPTSSGLPPGWEEK_
NEDD4 Ubiquitylation K874 0.127 _LK(gl)IPAHLR_
NEDD4 Ubiquitylation K882 -0.919 0.114 _GK(gl)TSLDTSNDLGPLPPGWEER_
NEDD4L Ubiquitylation K149 -0.001 0.036 _LK(gl)MAYMPK_
NEDD4L Phosphorylation T302 0.166 0.120 _T(ph)SPQELSEELSR_
NEDD4L Phosphorylation S303 0.166 0.120 _T(ph)SPQELSEELSR_
NEDD4L Phosphorylation S448 0.067 -0.137 _SLS(ph)SPTVTLSAPLEGAK_
NEDD4L Phosphorylation S449 -0.460 -0.435 _SLSS(ph)PTVTLSAPLEGAK_
NEDD4L Ubiquitylation K462 -0.635 -0.011 _SLSSPTVTLSAPLEGAK(gl)DSPVRR_
NEDD4L Ubiquitylation K471 -0.787 _AVK(gl)DTLSNPQSPQPSPYNSPKPQHK_
NEDD4L Ubiquitylation K531 0.704 _LK(gl)FPVHMR_
NEDD4L Ubiquitylation K539 -1.106 -1.175 _SK(gl)TSLNPNDLGPLPPGWEER_
NEDD4L Ubiquitylation K639 0.649 0.864 _IMSVK(gl)RPDVLK_
SGSM3 Ubiquitylation K730 -1.056 _EAQQPLK(gl)EGVR_
SNX1 Ubiquitylation K179 1.013 0.331 _SK(gl)QFAVK_
SNX1 Ubiquitylation K223 -0.206 _SLIGMTKVK(gl)_
TNFAIP3 Ubiquitylation K722 0.496 0.176 _ASCK(gl)NILACR_
TRIM32 Ubiquitylation K175 0.333 -0.305 _AALEGVSK(gl)DLQAR_
TRIM32 Ubiquitylation K204 1.221 _K(gl)FFTGSLAEVEK_
TRIM32 Ubiquitylation K405 2.753 _GFLK(gl)EIRR_
TRIM32 Ubiquitylation K506 0.638 _GSGVVK(gl)YSCLCSAVRPK_
VCP Phosphorylation S3 0.795 1.142 _(ac)AS(ph)GADSKGDDLSTAILK_
VCP Phosphorylation S7 0.312 0.941 _(ac)ASGADS(ph)KGDDLSTAILK_
VCP Ubiquitylation K8 -0.439 -0.154 _(ac)ASGADSK(gl)GDDLSTAILK_
VCP Ubiquitylation K18 -0.452 0.181 _GDDLSTAILK(gl)QK_
VCP Ubiquitylation K20 -0.512 0.529 _(ac)ASGADSKGDDLSTAILKQK(gl)_
VCP Ubiquitylation K60 0.678 0.493 _GDTVLLK(gl)GKK_
VCP Ubiquitylation K81 0.084 _EAVCIVLSDDTCSDEK(gl)IR_
VCP Ubiquitylation K109 -0.847 -0.260 _LGDVISIQPCPDVK(gl)YGK(gl)R_
VCP Ubiquitylation K112 -0.736 -0.276 _LGDVISIQPCPDVK(gl)YGK(gl)R_
VCP Ubiquitylation K148 -0.262 -0.087 _K(gl)GDIFLVR_
VCP Ubiquitylation K211 1.383 0.902 _K(gl)QLAQIK_
VCP Ubiquitylation K236 -0.526 -0.178 _AIGVK(gl)PPR_
VCP Ubiquitylation K251 -0.110 _GILLYGPPGTGK(gl)TLIAR_
VCP Ubiquitylation K336 0.522 _IVSQLLTLMDGLK(gl)QR_
VCP Ubiquitylation K386 1.339 0.706 _LEILQIHTK(gl)NM(ox)K_
VCP Ubiquitylation K389 0.568 1.195 _LEILQIHTKNMK(gl)_
VCP Ubiquitylation K505 0.377 0.794 _FLK(gl)FGMTPSK_
VCP Ubiquitylation K524 -0.528 _GVLFYGPPGCGK(gl)TLLAK_
VCP Ubiquitylation K529 -0.250 _GVLFYGPPGCGKTLLAK(gl)_
VCP Ubiquitylation K565 0.645 0.689 _EIFDK(gl)AR_
VCP Ubiquitylation K615 1.209 1.270 _VINQILTEMDGMSTKK(gl)_
VCP Ubiquitylation K651 -1.709 -0.719 _LDQLIYIPLPDEK(gl)SR_
VCP Ubiquitylation K658 0.362 0.711 _VAILK(gl)ANLR_
VCP Ubiquitylation K663 -0.839 _K(gl)SPVAKDVDLEFLAK_
VCP Ubiquitylation K668 -0.536 0.265 _SPVAK(gl)DVDLEFLAK_
VCP Ubiquitylation K696 1.574 1.691 _ACK(gl)LAIR_
VCP Ubiquitylation K754 0.510 0.939 _K(gl)YEMFAQTLQQSR_
WNT5A Ubiquitylation K268 -0.304 _VGDALK(gl)EK_
ZNF268 Ubiquitylation K193 0.095 _LCLLSTK(gl)YLSR_


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