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Query: BARD1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
BARD1 0 2.023 0.470 0.260

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
BARD1 Phosphorylation S186 0.193 0.942 _DASAQQDSYEFVSPS(ph)PPADVSER_
BARD1 Ubiquitylation K27 0.888 _VGVK(gl)ACLR_

Background Information for BARD1:


Pubmed-BARD1 »
Uniprot-BARD1 »
Biogrid-BARD1 »
ProteomicsDB-BARD1 »

Tumorportal-BARD1 »
COSMIC-BARD1 »
GenomeRNAi-BARD1 »
Genecards-BARD1


Protein-protein Interactions for BARD1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BRCA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait BRCA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in BARD1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members BRCT_dom IPR001357 1.59
Category members Znf_RING IPR001841 0
Category members Ankyrin_rpt IPR002110 0
Category members Ankyrin_rpt-contain_dom IPR020683 0


Protein complexes (CORUM database) featuring BARD1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2815 BRCA1-BARD1-BACH1-DNA damage complex II Database 1.57
Category members Corum 2817 BRCA1-BARD1-BACH1-DNA damage complex I Database 0.79
Category members Corum 2786 BRCA1 A complex Database 0.68
Category members Corum 2213 BRCA1-BARD1-POLR2A complex Database 0.66
Category members Corum 2787 BRCA1 C complex Database 0.66
Category members Corum 2823 BRCA1-BARD1-UbcH7c complex Database 0.57
Category members Corum 201 HUIC complex Database 0.28
Category members Corum 2783 BARD1-BRCA1-CSTF64 complex Database 0.06
Category members Corum 2788 BRCA1 B complex Database 0.06
Category members Corum 2818 BRCA1-BARD1-BRCA2-DNA damage complex III Database 0.06
Category members Corum 2822 BRCA1-BARD1-UbcH5c complex Database 0.06
Category members Corum 5288 P53-BARD1-Ku70 complex Database 0.06
Category members Corum 2211 BARD1-BRCA1-CSTF complex Database 0


Categories featuring BARD1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006974 cellular response to DNA damage stimulus Database 3.57
Category members Pathway Pathway_870 PID_BARD1_PATHWAY 0 2.44
Category members Disease phenotype Hereditary_breast_and_ovarian_cancer_syndrome Hereditary breast and ovarian cancer syndrome Database 1.23
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0019900 kinase binding Database 0.45
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0031436 BRCA1-BARD1 complex Database 0.28
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0000151 ubiquitin ligase complex Database 0.24
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0046826 negative regulation of protein export from nucleus Database 0.23
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members GO Category GO:0070531 BRCA1-A complex Database 0.04
Category members GO Category GO:0001894 tissue homeostasis Database 0
Category members GO Category GO:0007050 cell cycle arrest Database 0
Category members GO Category GO:0042325 regulation of phosphorylation Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0045732 positive regulation of protein catabolic process Database 0


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