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bioLOGIC Data

Query: ZNF268

RNAi screen result	RNAPII IP (PI)	CSB IP	CSB IP (PI)	Chrom.	Chrom. (PI)	Phosphorylation	Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
ZNF268	0	0.095	1.050	-0.230

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
ZNF268	Ubiquitylation	K193		0.095	_LCLLSTK(gl)YLSR_

Background Information for ZNF268:

Pubmed-ZNF268 »

Uniprot-ZNF268 »

Biogrid-ZNF268 »

ProteomicsDB-ZNF268 »

Tumorportal-ZNF268 »

COSMIC-ZNF268 »

GenomeRNAi-ZNF268 »

Genecards-ZNF268

Protein-protein Interactions for ZNF268

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait VBP1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait RBPJ	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait TRIM28	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in ZNF268

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	Krueppel-associated_box	IPR001909	2.12
Category members	Znf_C2H2-like	IPR015880	1.29
Category members	Znf_C2H2	IPR007087	0.92

Protein complexes (CORUM database) featuring ZNF268

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)

Categories featuring ZNF268

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	GO Category	GO:0005634	nucleus	Database	INF
Category members	GO Category	GO:0005737	cytoplasm	Database	12.81
Category members	GO Category	GO:0003677	DNA binding	Database	1.53
Category members	GO Category	GO:0006351	transcription, DNA-templated	Database	1.07
Category members	GO Category	GO:0003676	nucleic acid binding	Database	0.83
Category members	GO Category	GO:0003700	sequence-specific DNA binding transcription factor activity	Database	0.63
Category members	GO Category	GO:0043066	negative regulation of apoptotic process	Database	0.6
Category members	GO Category	GO:0045597	positive regulation of cell differentiation	Database	0.45
Category members	GO Category	GO:0005622	intracellular	Database	0.32
Category members	GO Category	GO:0008285	negative regulation of cell proliferation	Database	0.28
Category members	GO Category	GO:0001934	positive regulation of protein phosphorylation	Database	0.22
Category members	GO Category	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Database	0.13
Category members	GO Category	GO:0043497	regulation of protein heterodimerization activity	Database	0.07
Category members	GO Category	GO:0030154	cell differentiation	Database	0.06
Category members	GO Category	GO:0046022	positive regulation of transcription from RNA polymerase II promoter during mitosis	Database	0.04
Category members	GO Category	GO:0071356	cellular response to tumor necrosis factor	Database	0.03
Category members	GO Category	GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Database	0.02
Category members	GO Category	GO:0006355	regulation of transcription, DNA-dependent	Database	0
Category members	GO Category	GO:0007346	regulation of mitotic cell cycle	Database	0
Category members	GO Category	GO:0008284	positive regulation of cell proliferation	Database	0
Category members	GO Category	GO:0008588	release of cytoplasmic sequestered NF-kappaB	Database	0
Category members	GO Category	GO:0030335	positive regulation of cell migration	Database	0
Category members	GO Category	GO:0045732	positive regulation of protein catabolic process	Database	0
Category members	GO Category	GO:0046872	metal ion binding	Database	0
Category members	GO Category	GO:0071157	negative regulation of cell cycle arrest	Database	0