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Query: CSNK2A1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CSNK2A1 0 -0.062 0.050 -0.020 0.030 -0.550 1.362 0.022 -0.045

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CSNK2A1 Ubiquitylation K329 -0.661 -0.889 _EAMEHPYFYTVVK(gl)DQAR_
CSNK2A1 Ubiquitylation K71 0.008 _ILK(gl)PVKK_

Background Information for CSNK2A1:


Pubmed-CSNK2A1 »
Uniprot-CSNK2A1 »
Biogrid-CSNK2A1 »
ProteomicsDB-CSNK2A1 »

Tumorportal-CSNK2A1 »
COSMIC-CSNK2A1 »
GenomeRNAi-CSNK2A1 »
Genecards-CSNK2A1


Protein-protein Interactions for CSNK2A1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BRD2;DKFZp313H139 Cat. description Hein, Mann, Cell 2015
Category members IP bait CSNK2A2 Cat. description Hein, Mann, Cell 2015
Category members IP bait JARID1C;KDM5C Cat. description Hein, Mann, Cell 2015
Category members IP bait KIAA1430 Cat. description Hein, Mann, Cell 2015
Category members IP bait RNPS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait AKAP17A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AURKAIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C11orf57 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C14orf118 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C2orf3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CSNK2A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DCAF7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDX41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DVL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait E4F1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FXR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GLTSCR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HEXIM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HEXIM2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HLX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait JPH4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LLGL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPIN3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LUC7L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LUC7L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MLX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NKAP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NRP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCGF5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCGF6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PES1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PHC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POLR2E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRPF40A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF113A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF43 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RSRC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RYBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SREK1IP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SSRP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSPYL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TTLL7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSX2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YAF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZCCHC17 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF707 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZSCAN5A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CSNK2A1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Aminoglycoside_PTrfase IPR002575 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring CSNK2A1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 938 FACT complex, UV-activated Database 0.35
Category members Corum 2719 Casein kinase II-HMG1 complex Database 0.13
Category members Corum 2720 Casein kinase II complex Database 0
Category members Corum 5224 Casein kinase II (beta-dimer, alpha, alpha') Database 0
Category members Corum 5225 Casein kinase II (beta-dimer, alpha-dimer) Database 0


Categories featuring CSNK2A1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_292 PID_ECADHERIN_NASCENT_AJ_PATHWAY 0 2.74
Category members Pathway Pathway_413 KEGG_TIGHT_JUNCTION 0 2.08
Category members GO Category GO:0047485 protein N-terminus binding Database 1.84
Category members Pathway Pathway_1023 PID_NFAT_3PATHWAY 0 1.46
Category members Pathway Pathway_729 PID_LIS1_PATHWAY 0 1.41
Category members Pathway Pathway_1075 REACTOME_L1CAM_INTERACTIONS 0 1.32
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0016581 NuRD complex Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members Pathway Pathway_673 REACTOME_AXON_GUIDANCE 0 1.06
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0031519 PcG protein complex Database 0.62
Category members Pathway Pathway_1076 REACTOME_SIGNAL_TRANSDUCTION_BY_L1 0 0.44
Category members Pathway Pathway_747 KEGG_ADHERENS_JUNCTION 0 0.43
Category members GO Category GO:0008013 beta-catenin binding Database 0.35
Category members GO Category GO:0016580 Sin3 complex Database 0.35
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members GO Category GO:0046777 protein autophosphorylation Database 0.23
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0071174 mitotic spindle checkpoint Database 0.17
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members GO Category GO:0016055 Wnt signaling pathway Database 0.11
Category members Pathway Pathway_679 KEGG_WNT_SIGNALING_PATHWAY 0 0.09
Category members Pathway Pathway_578 BIOCARTA_EGF_PATHWAY 0 0.09
Category members Pathway Pathway_584 BIOCARTA_TPO_PATHWAY 0 0.08
Category members Pathway Pathway_941 BIOCARTA_WNT_PATHWAY 0 0.08
Category members Pathway Pathway_405 PID_ALPHA_SYNUCLEIN_PATHWAY 0 0.08
Category members Pathway Pathway_967 PID_DNA_PK_PATHWAY 0 0.04
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members Pathway Pathway_630 BIOCARTA_PDGF_PATHWAY 0 0.03
Category members Pathway Pathway_942 PID_PS1_PATHWAY 0 0.03
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members Pathway Pathway_1077 BIOCARTA_IL2_PATHWAY 0 0
Category members Pathway Pathway_1079 BIOCARTA_IL6_PATHWAY 0 0
Category members Pathway Pathway_290 WNT_SIGNALING 0 0
Category members Pathway Pathway_422 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY 0 0
Category members Pathway Pathway_531 PID_PDGFRA_PATHWAY 0 0
Category members Pathway Pathway_540 PID_BCR_5PATHWAY 0 0
Category members Pathway Pathway_577 BIOCARTA_INSULIN_PATHWAY 0 0
Category members Pathway Pathway_610 PID_NFKAPPAB_ATYPICAL_PATHWAY 0 0
Category members Pathway Pathway_627 BIOCARTA_NGF_PATHWAY 0 0
Category members Pathway Pathway_632 BIOCARTA_IGF1_PATHWAY 0 0
Category members Pathway Pathway_700 BIOCARTA_EPO_PATHWAY 0 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0019888 protein phosphatase regulator activity Database 0
Category members GO Category GO:0030177 positive regulation of Wnt signaling pathway Database 0
Category members GO Category GO:0030307 positive regulation of cell growth Database 0
Category members GO Category GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Database 0
Category members GO Category GO:0045732 positive regulation of protein catabolic process Database 0
Category members GO Category GO:0051879 Hsp90 protein binding Database 0
Category members GO Category GO:0061077 chaperone-mediated protein folding Database 0


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