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PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY
(Pathway_422)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
JUN 3 -0.930 0.930 -0.126
MAPK14 2 -0.160 -0.350
ATF2 2 -1.380 1.800
CSNK2A2 1 -2.450 5.260 1.102 -0.224 1.364 -0.368 -0.150
EIF4E 1 -2.250 4.200 0.590 0.156
EIF4E 1 -2.250 4.200 0.369
EIF4EBP1 1 2.050 -1.320
MEF2A 0 0.820 -0.530
MEF2A 0 0.820 -0.530
MEF2C 0 -0.980 1.550
MEF2C 0 -0.980 1.550
MAPKAPK5 0 1.100 -0.730
SLC9A1 0 1.000 -1.310
CSNK2A1 0 0.050 -0.020 0.030 -0.550 1.362 0.022 -0.045
HBP1 0 -1.130 1.580
HSPB1 0 0.710 -0.660 -0.632
ATF6 0 -0.290 0.500
CREB1 0 1.080 -0.800 -1.027
ATF1 0 0.500 0.320 -0.601 0.001
TP53 0 -1.070 1.050 -2.808 0.076 -0.094 0.436 0.497
RAB5A 0 -0.440 0.910 0.089 -0.362
RAB5A 0 0.080 0.240 0.089 -0.362
ELK4 0 0.620 -0.960
USF1 0 -0.540 1.070 0.151 -0.093
CEBPB 0 0.400 -0.930
CSNK2B 0 1.680 -0.760 0.254 -0.316 1.419 -0.407 -0.001

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ATF1 Phosphorylation S464 0.128 _TTPSATSLPQTVVMTS(ph)PVTLTSQTTK_
ATF1 Ubiquitylation K481 -0.754 _TDDPQLK(gl)R_
ATF1 Ubiquitylation K505 0.609 0.811 _EYVK(gl)CLENR_
ATF2 Phosphorylation T71 -1.263 -1.166 _NDSVIVADQTPT(ph)PTR_
ATF2 Phosphorylation S90 2.624 2.389 _NCEEVGLFNELAS(ph)PFENEFKK_
ATF2 Phosphorylation S112 1.025 1.118 _MPLDLS(ph)PLATPIIR_
ATF6 Ubiquitylation K87 -2.360 _DIK(gl)AEPQPLSPASSSYSVSSPR_
ATF6 Ubiquitylation K290 -0.035 _LSVTK(gl)PVLQSTMR_
ATF6 Ubiquitylation K339 0.296 _LK(gl)AALSENEQLKK_
ATF6 Ubiquitylation K436 0.653 _EAQDTSDGIIQK(gl)NSYR_
CEBPB Phosphorylation S231 -0.660 _AYLGYQAVPSGSSGSLSTSSSSS(ph)PPGTPSPADAK_
CREB1 Phosphorylation S271 -0.979 -1.450 _TAPTSTIAPGVVM(ox)ASS(ph)PALPTQPAEEAAR_
CREB1 Ubiquitylation K333 1.343 _ALK(gl)DLYCHK_
CSNK2A1 Ubiquitylation K71 0.008 _ILK(gl)PVKK_
CSNK2A1 Ubiquitylation K329 -0.661 -0.889 _EAMEHPYFYTVVK(gl)DQAR_
CSNK2B Phosphorylation S224 0.032 0.181 _IHPM(ox)AYQLQLQAAS(ph)NFKSPVK_
CSNK2B Phosphorylation S228 0.032 -0.025 _IHPM(ox)AYQLQLQAASNFKS(ph)PVK_
CSNK2B Ubiquitylation K231 -1.221 _SPVK(gl)TIR_
EIF4E Ubiquitylation K147 -0.433 0.065 _WLITLNK(gl)QQR_
EIF4EBP1 Phosphorylation Y34 -1.060 _RVVLGDGVQLPPGDY(ph)STTPGGTLFS(ph)TTPGGTR_
EIF4EBP1 Phosphorylation S35 -0.849 _RVVLGDGVQLPPGDYS(ph)TTPGGTLFS(ph)TTPGGTR_
EIF4EBP1 Phosphorylation T37 -0.768 -0.583 _RVVLGDGVQLPPGDYSTT(ph)PGGTLFSTT(ph)PGGTR_
EIF4EBP1 Phosphorylation T41 -3.655 -0.903 _RVVLGDGVQLPPGDYST(ph)TPGGT(ph)LFSTTPGGTR_
EIF4EBP1 Phosphorylation S44 -0.796 _VVLGDGVQLPPGDYSTTPGGTLFS(ph)T(ph)TPGGTR_
EIF4EBP1 Phosphorylation T45 -0.727 _VVLGDGVQLPPGDYSTTPGGTLFS(ph)T(ph)TPGGTR_
EIF4EBP1 Phosphorylation T46 -0.890 -0.817 _RVVLGDGVQLPPGDYSTT(ph)PGGTLFSTT(ph)PGGTR_
EIF4EBP1 Phosphorylation S65 0.522 0.478 _NS(ph)PVTKT(ph)PPR_
EIF4EBP1 Phosphorylation T68 -1.621 -2.402 _NS(ph)PVT(ph)KTPPRDLPTIPGVTSPSSDEPPMEASQSHLR_
EIF4EBP1 Ubiquitylation K69 -1.171 -1.547 _NSPVTK(gl)TPPR_
EIF4EBP1 Phosphorylation T70 -0.702 -0.017 _NSPVTKT(ph)PPR_
EIF4EBP1 Phosphorylation T77 -1.921 -1.898 _TPPRDLPT(ph)IPGVTSPSSDEPPMEASQSHLR_
EIF4EBP1 Phosphorylation T82 1.253 _DLPTIPGVT(ph)SPSSDEPPMEASQSHLR_
EIF4EBP1 Phosphorylation S83 1.211 0.339 _DLPTIPGVTS(ph)PSSDEPPMEASQSHLR_
EIF4EBP1 Phosphorylation S96 -1.541 _DLPTIPGVTSPSSDEPPMEASQS(ph)HLRNSPEDK_
EIF4EBP1 Phosphorylation S101 -1.900 -1.976 _DLPTIPGVTSPSSDEPPMEASQSHLRNS(ph)PEDK_
ELK4 Phosphorylation S305 -0.891 _KPPVEPVAATISIGPSIS(ph)PSSEETIQALETLVSPK_
HBP1 Ubiquitylation K426 -1.246 _NCGSPGSSQLSSNSLYAK(gl)AVK_
HSPB1 Phosphorylation S82 1.036 0.723 _QLS(ph)SGVSEIR_
HSPB1 Ubiquitylation K198 -1.654 _AQLGGPEAAK(gl)SDETAAK_
JUN Phosphorylation S58 -0.167 -1.247 _AKNS(ph)DLLTSPDVGLLK_
JUN Phosphorylation T62 2.545 1.674 _NSDLLT(ph)SPDVGLLK_
JUN Phosphorylation S63 2.030 1.458 _NSDLLTS(ph)PDVGLLK_
JUN Ubiquitylation K70 9.213 _NSDLLTSPDVGLLK(gl)_
JUN Phosphorylation S73 1.499 0.845 _LAS(ph)PELER_
JUN Phosphorylation S243 -0.642 -1.399 _LQALKEEPQTVPEMPGETPPLS(ph)PIDMESQER_
JUN Ubiquitylation K309 1.034 0.155 _EQVAQLK(gl)QK_
MAPK14 Phosphorylation S2 3.221 3.623 _(ac)S(ph)QERPTFYR_
MAPK14 Phosphorylation T180 0.958 1.087 _HTDDEM(ox)T(ph)GYVATR_
MAPK14 Phosphorylation Y182 1.388 1.374 _HTDDEM(ox)TGY(ph)VATR_
MAPK14 Ubiquitylation K249 0.073 -1.380 _LVGTPGAELLKK(gl)_
MAPKAPK5 Phosphorylation T182 -0.559 -0.706 _IDQGDLM(ox)T(ph)PQFTPYYVAPQVLEAQR_
MEF2A Ubiquitylation K23 -0.140 _QVTFTK(gl)R_
MEF2A Phosphorylation S235 0.664 -0.092 _AS(ph)PNLIGATGANSLGK_
MEF2A Phosphorylation T253 -1.271 _VMPT(ph)KSPPPPGGGNLGMNSR_
MEF2A Phosphorylation S255 -1.235 _VMPTKS(ph)PPPPGGGNLGMNSR_
MEF2A Phosphorylation S408 -0.173 -0.049 _SEPIS(ph)PPRDR_
MEF2A Phosphorylation S494 -0.858 -1.232 _GDFHSPIVLGRPPNTEDRES(ph)PSVK_
MEF2C Ubiquitylation K23 -0.140 _QVTFTK(gl)R_
MEF2C Phosphorylation S240 0.008 0.302 _NS(ph)PGLLVSPGNLNK_
MEF2C Phosphorylation S406 0.272 0.338 _SEPVS(ph)PPRDR_
SLC9A1 Phosphorylation S693 0.458 0.404 _INNYLTVPAHKLDS(ph)PTM(ox)SR_
SLC9A1 Phosphorylation S703 -0.097 0.010 _IGS(ph)DPLAYEPK_
SLC9A1 Phosphorylation S785 -0.871 -0.971 _ETSSPGTDDVFTPAPSDS(ph)PSSQR_
TP53 Ubiquitylation K120 -0.188 _LGFLHSGTAK(gl)SVTCTYSPALNK_
TP53 Ubiquitylation K164 0.157 -1.260 _AMAIYK(gl)QSQHMTEVVR_
TP53 Phosphorylation S314 -0.695 -1.000 _ALPNNTSS(ph)SPQPK_
TP53 Phosphorylation S315 -0.762 -0.959 _RALPNNTSSS(ph)PQPK_
TP53 Ubiquitylation K320 -0.978 _ALPNNTSSSPQPKK(gl)_
TP53 Ubiquitylation K357 -0.231 -0.823 _ELNEALELKDAQAGK(gl)EPGGSR_
USF1 Ubiquitylation K269 -0.265 0.440 _IIPDCNADNSK(gl)TGASK_
USF1 Phosphorylation S279 -0.121 0.837 _GGILS(ph)KACDYIR_
USF1 Ubiquitylation K300 -0.172 _MQETFK(gl)EAER_


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