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Query: ELK4

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ELK4 0 -0.891 0.620 -0.960

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ELK4 Phosphorylation S305 -0.891 _KPPVEPVAATISIGPSIS(ph)PSSEETIQALETLVSPK_

Background Information for ELK4:


Pubmed-ELK4 »
Uniprot-ELK4 »
Biogrid-ELK4 »
ProteomicsDB-ELK4 »

Tumorportal-ELK4 »
COSMIC-ELK4 »
GenomeRNAi-ELK4 »
Genecards-ELK4


Protein-protein Interactions for ELK4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KIFC1 Cat. description Hein, Mann, Cell 2015


Protein Domains in ELK4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ets_dom IPR000418 0.07


Protein complexes (CORUM database) featuring ELK4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1890 ELK1-SRF-ELK4 complex Database 0.3


Categories featuring ELK4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0003712 transcription cofactor activity Database 0.21
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0001047 core promoter binding Database 0.11
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members Pathway Pathway_422 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY 0 0
Category members Pathway Pathway_715 KEGG_MAPK_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0070932 histone H3 deacetylation Database 0


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