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Query: MAPKAPK5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MAPKAPK5 0 -1.265 1.100 -0.730

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MAPKAPK5 Phosphorylation T182 -0.559 -0.706 _IDQGDLM(ox)T(ph)PQFTPYYVAPQVLEAQR_

Background Information for MAPKAPK5:


Pubmed-MAPKAPK5 »
Uniprot-MAPKAPK5 »
Biogrid-MAPKAPK5 »
ProteomicsDB-MAPKAPK5 »

Tumorportal-MAPKAPK5 »
COSMIC-MAPKAPK5 »
GenomeRNAi-MAPKAPK5 »
Genecards-MAPKAPK5


Protein-protein Interactions for MAPKAPK5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MAPK6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MAPKAPK5
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members LipoPS_kinase IPR010440 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring MAPKAPK5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MAPKAPK5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0002039 p53 binding Database 2.06
Category members Pathway Pathway_608 SIG_CD40PATHWAYMAP 0 0.89
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_983 ST_P38_MAPK_PATHWAY 0 0.34
Category members GO Category GO:0032007 negative regulation of TOR signaling Database 0.33
Category members GO Category GO:0046777 protein autophosphorylation Database 0.23
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0051019 mitogen-activated protein kinase binding Database 0.13
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members Pathway Pathway_1000 BIOCARTA_MAPK_PATHWAY 0 0
Category members Pathway Pathway_422 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY 0 0
Category members Pathway Pathway_715 KEGG_MAPK_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_723 BIOCARTA_P38MAPK_PATHWAY 0 0
Category members GO Category GO:0000165 MAPK cascade Database 0
Category members GO Category GO:0000187 activation of MAPK activity Database 0
Category members GO Category GO:0004708 MAP kinase kinase activity Database 0
Category members GO Category GO:0006417 regulation of translation Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007265 Ras protein signal transduction Database 0
Category members GO Category GO:0009103 lipopolysaccharide biosynthetic process Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0016773 phosphotransferase activity, alcohol group as acceptor Database 0


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