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Results for the Category
activation of MAPK activity
(GO:0000187)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
RPS27A 4 -1.330 2.560 -0.309 0.131 -0.009
UBC 3 -0.309 0.131 -0.009
UBC 3
UBC 3
UBB 3 -0.309 0.131 -0.009
UBA52 3 -1.260 2.180 -0.309 0.131 -0.009
UBA52 3 -1.260 2.180
SPAG9 2 -0.110 0.210 1.305
MAPK14 2 -0.160 -0.350
TAB3 2 -0.550 1.560 0.022 -0.207
TAB3 2 -0.550 1.560
INSR 2 -0.850 0.830 1.143 0.785
TAB1 1 1.890 -0.670
TAB1 1 1.890 -0.670 1.657
RIPK2 1 -1.740 3.580
MAP2K1 1 -1.590 2.780
MAP2K3 0 0.780 -0.600
PIK3CB 0 -1.390 2.350
PIK3CB 0 -0.710 1.450
TAB2 0 -0.030 -0.580
IKBKG 0
MAPKAPK5 0 1.100 -0.730
PXN 0 1.020 -0.760
MAPK3 0
MET 0 -0.010 -0.330
MAP2K6 0 1.270 -0.780
GAB1 0 1.950 -1.110
MADD 0 0.620 -1.050
CD81 0 0.850 -0.400 0.408 0.204
WNT5A 0
TGFB3 0 0.900 -0.540
CXCR4 0 0.640 -0.440
MAP2K2 0 -0.610 0.080
MAP2K2 0 -0.610 0.080
PRKAA1 0 0.910 0.060
MAP3K7 0 -1.120 1.140 -1.048
ARRB1 0 0.960 -0.620
PLCE1 0 0.540 -0.070
SOD1 0 1.450 -1.250
MAP3K2 0 -1.220 1.960
CDK1 0 -0.370 0.080 -0.202 -0.884 -0.107 -0.097 -0.501
ADORA2B 0 -0.080 0.070
PTPN11 0 -0.210 -0.400 0.644 1.053 0.451
IQGAP3 0 1.720 -1.070 0.165 0.274
LRRK2 0 0.530 -0.620 -0.240
MAP3K5 0 0.710 -0.770
ITGA1 0 -0.750 1.480 0.650 0.069

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ADORA2B Ubiquitylation K303 0.335 _YTFHK(gl)IISR_
ARRB1 Phosphorylation S412 0.138 0.253 _GMKDDKEEEEDGTGS(ph)PQLNNR_
CD81 Ubiquitylation K182 -2.166 _QFYDQALQQAVVDDDANNAK(gl)AVVK_
CDK1 Ubiquitylation K6 0.011 -0.784 _(ac)M(ox)EDYTK(gl)IEK_
CDK1 Ubiquitylation K20 -0.327 -0.270 _IGEGTYGVVYK(gl)GR_
CDK1 Ubiquitylation K33 0.736 0.239 _TTGQVVAMK(gl)K_
CDK1 Ubiquitylation K34 -0.306 _TTGQVVAMKK(gl)_
CDK1 Ubiquitylation K58 0.312 -0.262 _EISLLK(gl)ELR_
CDK1 Ubiquitylation K136 -0.468 _DLK(gl)PQNLLIDDK(gl)GTIK_
CDK1 Ubiquitylation K145 0.161 -0.954 _DLKPQNLLIDDK(gl)GTIK_
CDK1 Ubiquitylation K149 -0.038 _GTIK(gl)LADFGLAR_
CDK1 Ubiquitylation K251 -0.047 -1.236 _WK(gl)PGSLASHVK_
CDK1 Ubiquitylation K280 0.179 -1.210 _MLIYDPAK(gl)R_
CXCR4 Phosphorylation S319 0.861 -0.615 _TSAQHALTS(ph)VSR_
CXCR4 Ubiquitylation K327 0.978 0.329 _GSSLK(gl)ILSK_
GAB1 Phosphorylation S266 0.756 0.551 _SYS(ph)HDVLPK_
GAB1 Phosphorylation S367 0.230 0.176 _TAS(ph)DTDSSYCIPTAGMS(ph)PSR_
GAB1 Phosphorylation T369 -0.352 _TASDT(ph)DSSYCIPTAGMS(ph)PSR_
GAB1 Phosphorylation S381 -0.481 0.139 _TASDTDSSYCIPTAGM(ox)S(ph)PSR_
GAB1 Phosphorylation S401 0.266 0.788 _DAS(ph)SQDCYDIPR_
GAB1 Phosphorylation S402 0.328 0.633 _DASS(ph)QDCYDIPR_
GAB1 Phosphorylation S419 0.540 _SSS(ph)LEGFHNHFK_
IKBKG Ubiquitylation K285 -1.202 -0.389 _QEVIDKLK(gl)EEAEQHK_
IKBKG Ubiquitylation K309 0.123 0.725 _AQADIYK(gl)ADFQAER_
IKBKG Ubiquitylation K344 0.060 _LK(gl)ASCQESAR_
IKBKG Phosphorylation S387 -1.270 -1.418 _S(ph)PPEEPPDFCCPK_
INSR Ubiquitylation K1022 -0.603 _EK(gl)ITLLR_
INSR Ubiquitylation K1047 0.305 0.711 _DIIK(gl)GEAETR_
INSR Ubiquitylation K1057 0.482 0.484 _VAVK(gl)TVNESASLR_
INSR Ubiquitylation K1352 1.606 2.754 _DGGSSLGFK(gl)R_
IQGAP3 Ubiquitylation K661 0.344 _ALESAMAKK(gl)_
IQGAP3 Phosphorylation T1426 -0.517 _SLT(ph)AHSLLPLAEK_
MADD Phosphorylation S1059 0.390 0.618 _KRS(ph)PTESVNTPVGK_
MADD Phosphorylation T1061 0.390 0.682 _KRS(ph)PTESVNTPVGK_
MADD Phosphorylation T1237 -0.523 -0.591 _GT(ph)LSDSEIETNSATSTIFGK_
MADD Phosphorylation S1239 0.070 -0.211 _GTLS(ph)DSEIETNSATSTIFGK_
MAP2K1 Ubiquitylation K192 -0.205 -0.241 _DVK(gl)PSNILVNSR_
MAP2K1 Phosphorylation S385 0.066 _RSDAEEVDFAGWLCSTIGLNQPS(ph)TPTHAAGV_
MAP2K1 Phosphorylation T386 0.377 _RSDAEEVDFAGWLCSTIGLNQPST(ph)PTHAAGV_
MAP2K2 Phosphorylation S23 0.873 0.258 _RKPVLPALTINPTIAEGPS(ph)PTSEGASEANLVDLQK_
MAP2K2 Phosphorylation T25 0.439 _RKPVLPALTINPTIAEGPSPT(ph)SEGASEANLVDLQK_
MAP2K2 Ubiquitylation K192 -0.205 -0.241 _DVK(gl)PSNILVNSR_
MAP2K2 Phosphorylation S293 -0.361 _ELEAIFGRPVVDGEEGEPHS(ph)ISPR_
MAP2K2 Phosphorylation S295 -0.234 0.026 _ELEAIFGRPVVDGEEGEPHSIS(ph)PR_
MAP2K2 Phosphorylation T394 0.570 0.158 _LNQPGT(ph)PTR_
MAP2K3 Ubiquitylation K84 0.045 -0.277 _GAYGVVEK(gl)VR_
MAP2K3 Ubiquitylation K232 -1.394 _TMDAGCK(gl)PYMAPER_
MAP2K3 Ubiquitylation K247 0.065 -0.737 _INPELNQK(gl)GYNVK_
MAP2K6 Phosphorylation T28 -1.813 -0.792 _EAFEQPQTSST(ph)PPRDLDSK_
MAP2K6 Ubiquitylation K232 0.220 _INPELNQK(gl)GYSVK_
MAP3K2 Phosphorylation S153 0.506 -0.231 _RLS(ph)IIGPTSR_
MAP3K2 Phosphorylation S163 -0.910 -0.776 _DRS(ph)SPPPGYIPDELHQVAR_
MAP3K2 Phosphorylation S164 -0.743 -0.966 _DRS(ph)SPPPGYIPDELHQVAR_
MAP3K2 Phosphorylation S239 -0.284 -0.618 _AQS(ph)YPDNHQEFSDYDNPIFEK_
MAP3K2 Phosphorylation S331 0.008 _RRGS(ph)DIDNPTLTVM(ox)DISPPSR_
MAP3K5 Phosphorylation S1066 -1.241 _SISLPVPVLVEDTSSSSEYGSVS(ph)PDTELKVDPFSFK_
MAP3K5 Phosphorylation S1113 -1.408 -0.562 _TLFLGIPDENFEDHSAPPS(ph)PEEK_
MAP3K7 Phosphorylation S374 0.149 -0.337 _GS(ph)SVESLPPTSEGK_
MAP3K7 Phosphorylation S375 0.171 -0.087 _GSS(ph)VESLPPTSEGK_
MAP3K7 Phosphorylation S389 1.072 1.445 _RMS(ph)ADMSEIEAR_
MAP3K7 Phosphorylation S439 0.246 0.198 _S(ph)IQDLTVTGTEPGQVSSR_
MAP3K7 Ubiquitylation K474 -0.385 -0.242 _MITTSGPTSEK(gl)PTR_
MAP3K7 Ubiquitylation K589 -0.104 _SLSTYYQQCK(gl)K_
MAP3K7 Ubiquitylation K590 -0.551 0.560 _K(gl)QLEVIR_
MAPK14 Phosphorylation S2 3.221 3.623 _(ac)S(ph)QERPTFYR_
MAPK14 Phosphorylation T180 0.958 1.087 _HTDDEM(ox)T(ph)GYVATR_
MAPK14 Phosphorylation Y182 1.388 1.374 _HTDDEM(ox)TGY(ph)VATR_
MAPK14 Ubiquitylation K249 0.073 -1.380 _LVGTPGAELLKK(gl)_
MAPK3 Phosphorylation Y204 -0.807 -2.487 _IADPEHDHTGFLTEY(ph)VATR_
MAPK3 Ubiquitylation K289 -0.608 _NYLQSLPSKTK(gl)_
MAPKAPK5 Phosphorylation T182 -0.559 -0.706 _IDQGDLM(ox)T(ph)PQFTPYYVAPQVLEAQR_
MET Ubiquitylation K962 0.146 _QIK(gl)DLGSELVR_
MET Phosphorylation S988 0.064 _S(ph)VSPTTEM(ox)VSNESVDYR_
MET Phosphorylation S990 0.192 -0.105 _SVS(ph)PTTEM(ox)VSNESVDYR_
MET Phosphorylation T992 0.501 -0.048 _SVSPT(ph)TEMVSNESVDYR_
MET Phosphorylation S997 0.285 _S(ph)VSPTTEMVS(ph)NESVDYR_
PIK3CB Ubiquitylation K1044 0.990 _SEEEALKQFKQK(gl)_
PLCE1 Phosphorylation S1096 -0.120 0.294 _GES(ph)GEVTDDEMATR_
PRKAA1 Ubiquitylation K271 -0.536 _ATIK(gl)DIR_
PRKAA1 Ubiquitylation K396 -0.419 _HTLDELNPQK(gl)SK_
PRKAA1 Ubiquitylation K485 -1.326 -1.554 _SIDDEITEAK(gl)SGTATPQR_
PTPN11 Ubiquitylation K124 0.562 _EAEK(gl)LLTEK_
PXN Phosphorylation S85 -0.156 0.192 _FIHQQPQSSS(ph)PVYGSSAK_
PXN Phosphorylation T136 1.322 _SAEPSPTVMST(ph)SLGSNLSELDR_
PXN Phosphorylation S140 -0.291 -0.948 _SAEPSPTVM(ox)STSLGS(ph)NLSELDR_
PXN Phosphorylation S302 -0.167 _S(ph)SPGGQDEGGFMAQGK_
PXN Phosphorylation S303 -0.167 _S(ph)SPGGQDEGGFMAQGK_
PXN Phosphorylation S322 -1.234 _TGSSS(ph)PPGGPPKPGSQLDSMLGSLQSDLNK_
RIPK2 Ubiquitylation K410 -2.810 _AAFCDHK(gl)TTPCSSAIINPLSTAGNSER_
RIPK2 Phosphorylation S531 0.884 0.839 _SPS(ph)LNLLQNK_
RIPK2 Ubiquitylation K538 -2.659 _SPSLNLLQNK(gl)SM_
RPS27A Ubiquitylation K6 1.066 0.995 _MQIFVK(gl)TLTGK_
RPS27A Ubiquitylation K11 -0.488 -0.081 _TLTGK(gl)TITLEVEPSDTIENVKAK(gl)_
RPS27A Ubiquitylation K27 -0.882 -0.159 _TLTGK(gl)TITLEVEPSDTIENVK(gl)AK_
RPS27A Ubiquitylation K29 -1.087 -1.029 _AK(gl)IQDK(gl)EGIPPDQQR_
RPS27A Ubiquitylation K33 -0.736 -0.407 _IQDK(gl)EGIPPDQQR_
RPS27A Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
RPS27A Phosphorylation S57 1.909 0.548 _TLS(ph)DYNIQK_
RPS27A Ubiquitylation K63 0.276 0.299 _TLSDYNIQK(gl)ESTLHLVLR_
RPS27A Ubiquitylation K99 0.109 2.111 _VK(gl)LAVLK_
RPS27A Ubiquitylation K104 0.674 2.102 _LAVLK(gl)YYK_
RPS27A Ubiquitylation K107 2.949 3.611 _YYK(gl)VDENGK(gl)ISR_
RPS27A Ubiquitylation K113 1.572 3.672 _YYK(gl)VDENGK(gl)ISR_
RPS27A Ubiquitylation K152 4.747 4.970 _CCLTYCFNK(gl)PEDK_
RPS27A Ubiquitylation K156 4.809 _CCLTYCFNKPEDK(gl)_
SOD1 Ubiquitylation K4 -0.329 _(ac)ATK(gl)AVCVLK_
SOD1 Ubiquitylation K10 0.211 0.582 _AVCVLK(gl)GDGPVQGIINFEQK_
SOD1 Ubiquitylation K24 -0.435 -0.086 _GDGPVQGIINFEQK(gl)ESNGPVK_
SOD1 Ubiquitylation K31 -0.109 0.332 _ESNGPVK(gl)VWGSIK_
SOD1 Phosphorylation S99 0.405 _HVGDLGNVTADKDGVADVS(ph)IEDSVISLSGDHCIIGR_
SOD1 Ubiquitylation K123 0.352 0.004 _TLVVHEK(gl)ADDLGK_
SOD1 Ubiquitylation K129 0.143 _ADDLGK(gl)GGNEESTK_
SOD1 Ubiquitylation K137 0.464 0.934 _ADDLGKGGNEESTK(gl)TGNAGSR_
SPAG9 Ubiquitylation K178 0.616 _TK(gl)LHQLSGSDQLESTAHSR_
SPAG9 Phosphorylation S183 -0.041 0.617 _LHQLS(ph)GSDQLESTAHSR_
SPAG9 Phosphorylation S185 -0.229 0.589 _LHQLSGS(ph)DQLESTAHSR_
SPAG9 Phosphorylation S203 -0.173 0.319 _ERPIS(ph)LGIFPLPAGDGLLT(ph)PDAQK_
SPAG9 Phosphorylation T217 1.022 0.515 _ERPIS(ph)LGIFPLPAGDGLLT(ph)PDAQK_
SPAG9 Phosphorylation T226 2.211 2.141 _GGET(ph)PGSEQWK_
SPAG9 Phosphorylation T275 2.752 _AT(ph)TPASTANSDVATIPTDTPLKEENEGFVK_
SPAG9 Phosphorylation T276 2.516 2.823 _ATT(ph)PASTANSDVATIPTDTPLKEENEGFVK_
SPAG9 Phosphorylation T292 2.076 1.667 _ATTPASTANSDVATIPTDT(ph)PLKEENEGFVK_
SPAG9 Phosphorylation T330 0.261 _NVST(ph)GSAENEEKSEVQAIIESTPELDMDKDLSGYK_
SPAG9 Phosphorylation S339 -0.150 0.210 _NVSTGSAENEEKS(ph)EVQAIIESTPELDMDKDLSGYK_
SPAG9 Phosphorylation S593 0.642 _KRS(ph)STLSQLPGDK_
SPAG9 Phosphorylation S594 0.719 0.528 _RSS(ph)TLSQLPGDK_
SPAG9 Phosphorylation T595 0.585 _KRSST(ph)LSQLPGDK_
SPAG9 Ubiquitylation K653 -0.358 _VQAFGWSLPQK(gl)YK_
SPAG9 Ubiquitylation K699 -0.277 _LWCAVGVNLSGGK(gl)TR_
SPAG9 Phosphorylation S728 0.903 -0.047 _S(ph)ASQSSLDKLDQELKEQQK_
SPAG9 Phosphorylation S730 0.163 0.677 _SAS(ph)QSSLDKLDQELK_
SPAG9 Phosphorylation S732 0.961 0.900 _SASQS(ph)SLDKLDQELKEQQK_
SPAG9 Phosphorylation S733 0.740 0.712 _SASQSS(ph)LDKLDQELK_
SPAG9 Phosphorylation S813 0.253 _ETDYPAGEDLS(ph)ESGQVDK_
SPAG9 Phosphorylation S815 -0.037 _ETDYPAGEDLSES(ph)GQVDK_
SPAG9 Phosphorylation T1264 -1.557 -1.235 _AGPSAQEPGSQT(ph)PLK_
TAB1 Phosphorylation S7 -0.170 0.140 _S(ph)LLQSEQQPSWTDDLPLCHLSGVGSASNR_
TAB1 Phosphorylation S16 -0.138 0.069 _SLLQSEQQPS(ph)WTDDLPLCHLSGVGSASNR_
TAB1 Ubiquitylation K186 -1.015 _SYSADGK(gl)GTESHPPEDSWLK_
TAB1 Ubiquitylation K371 0.032 _LSQLGLDAGK(gl)IK_
TAB1 Ubiquitylation K373 -0.007 _LSQLGLDAGKIK(gl)_
TAB2 Phosphorylation S580 -0.075 _S(ph)NSISQIPSLEEMQQLR_
TAB2 Phosphorylation S582 0.331 _SNS(ph)ISQIPSLEEMQQLR_
TAB2 Ubiquitylation K653 -0.519 -0.200 _SIIK(gl)TPK_
TAB3 Phosphorylation S4 3.009 1.852 _(ac)AQS(ph)SPQLDIQVLHDLR_
TAB3 Phosphorylation S5 3.009 1.852 _(ac)AQS(ph)SPQLDIQVLHDLR_
TGFB3 Ubiquitylation K50 -0.557 _GQILSK(gl)LR_
UBA52 Ubiquitylation K6 1.066 0.995 _MQIFVK(gl)TLTGK_
UBA52 Ubiquitylation K11 -0.488 -0.081 _TLTGK(gl)TITLEVEPSDTIENVKAK(gl)_
UBA52 Ubiquitylation K27 -0.882 -0.159 _TLTGK(gl)TITLEVEPSDTIENVK(gl)AK_
UBA52 Ubiquitylation K29 -1.087 -1.029 _AK(gl)IQDK(gl)EGIPPDQQR_
UBA52 Ubiquitylation K33 -0.736 -0.407 _IQDK(gl)EGIPPDQQR_
UBA52 Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBA52 Phosphorylation S57 1.909 0.548 _TLS(ph)DYNIQK_
UBA52 Ubiquitylation K63 0.276 0.299 _TLSDYNIQK(gl)ESTLHLVLR_
UBA52 Ubiquitylation K93 0.181 2.418 _YNCDK(gl)MICR_
UBA52 Ubiquitylation K99 0.109 2.111 _VK(gl)LAVLK_
UBA52 Ubiquitylation K104 0.674 2.102 _LAVLK(gl)YYK_
UBA52 Ubiquitylation K107 2.949 3.611 _YYK(gl)VDENGK(gl)ISR_
UBA52 Ubiquitylation K113 1.572 3.672 _YYK(gl)VDENGK(gl)ISR_
UBA52 Ubiquitylation K152 4.747 4.970 _CCLTYCFNK(gl)PEDK_
UBA52 Ubiquitylation K156 4.809 _CCLTYCFNKPEDK(gl)_
UBB Ubiquitylation K6 1.066 0.995 _MQIFVK(gl)TLTGK_
UBB Ubiquitylation K11 -0.488 -0.081 _TLTGK(gl)TITLEVEPSDTIENVKAK(gl)_
UBB Ubiquitylation K27 -0.882 -0.159 _TLTGK(gl)TITLEVEPSDTIENVK(gl)AK_
UBB Ubiquitylation K29 -1.087 -1.029 _AK(gl)IQDK(gl)EGIPPDQQR_
UBB Ubiquitylation K33 -0.736 -0.407 _IQDK(gl)EGIPPDQQR_
UBB Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBB Phosphorylation S57 1.909 0.548 _TLS(ph)DYNIQK_
UBB Ubiquitylation K63 0.276 0.299 _TLSDYNIQK(gl)ESTLHLVLR_
UBB Ubiquitylation K99 0.109 2.111 _VK(gl)LAVLK_
UBB Ubiquitylation K104 0.674 2.102 _LAVLK(gl)YYK_
UBB Ubiquitylation K107 2.949 3.611 _YYK(gl)VDENGK(gl)ISR_
UBB Ubiquitylation K113 1.572 3.672 _YYK(gl)VDENGK(gl)ISR_
UBB Ubiquitylation K152 4.747 4.970 _CCLTYCFNK(gl)PEDK_
UBB Ubiquitylation K156 4.809 _CCLTYCFNKPEDK(gl)_
UBC Ubiquitylation K6 1.066 0.995 _MQIFVK(gl)TLTGK_
UBC Ubiquitylation K11 -0.488 -0.081 _TLTGK(gl)TITLEVEPSDTIENVKAK(gl)_
UBC Ubiquitylation K27 -0.882 -0.159 _TLTGK(gl)TITLEVEPSDTIENVK(gl)AK_
UBC Ubiquitylation K29 -1.087 -1.029 _AK(gl)IQDK(gl)EGIPPDQQR_
UBC Ubiquitylation K33 -0.736 -0.407 _IQDK(gl)EGIPPDQQR_
UBC Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBC Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBC Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBC Phosphorylation S57 1.909 0.548 _TLS(ph)DYNIQK_
UBC Ubiquitylation K63 0.276 0.299 _TLSDYNIQK(gl)ESTLHLVLR_
UBC Ubiquitylation K99 0.109 2.111 _VK(gl)LAVLK_
UBC Ubiquitylation K104 0.674 2.102 _LAVLK(gl)YYK_
UBC Ubiquitylation K107 2.949 3.611 _YYK(gl)VDENGK(gl)ISR_
UBC Ubiquitylation K113 1.572 3.672 _YYK(gl)VDENGK(gl)ISR_
UBC Ubiquitylation K152 4.747 4.970 _CCLTYCFNK(gl)PEDK_
UBC Ubiquitylation K156 4.809 _CCLTYCFNKPEDK(gl)_
WNT5A Ubiquitylation K268 -0.304 _VGDALK(gl)EK_


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