bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: MAP3K2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MAP3K2 0 2.474 -1.220 1.960

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MAP3K2 Phosphorylation S331 0.008 _RRGS(ph)DIDNPTLTVM(ox)DISPPSR_
MAP3K2 Phosphorylation S153 0.506 -0.231 _RLS(ph)IIGPTSR_
MAP3K2 Phosphorylation S239 -0.284 -0.618 _AQS(ph)YPDNHQEFSDYDNPIFEK_
MAP3K2 Phosphorylation S163 -0.910 -0.776 _DRS(ph)SPPPGYIPDELHQVAR_
MAP3K2 Phosphorylation S164 -0.743 -0.966 _DRS(ph)SPPPGYIPDELHQVAR_

Background Information for MAP3K2:


Pubmed-MAP3K2 »
Uniprot-MAP3K2 »
Biogrid-MAP3K2 »
ProteomicsDB-MAP3K2 »

Tumorportal-MAP3K2 »
COSMIC-MAP3K2 »
GenomeRNAi-MAP3K2 »
Genecards-MAP3K2


Protein-protein Interactions for MAP3K2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MAP3K2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAP2K5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MAP3K2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members OPR_PB1 IPR000270 0
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring MAP3K2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MAP3K2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_579 PID_ERBB1_DOWNSTREAM_PATHWAY 0 1.97
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0000186 activation of MAPKK activity Database 0.16
Category members Pathway Pathway_213 KEGG_GAP_JUNCTION 0 0.11
Category members GO Category GO:0004709 MAP kinase kinase kinase activity Database 0.08
Category members GO Category GO:0007257 activation of JUN kinase activity Database 0.08
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members Pathway Pathway_1000 BIOCARTA_MAPK_PATHWAY 0 0
Category members Pathway Pathway_1006 PID_MAPK_TRK_PATHWAY 0 0
Category members Pathway Pathway_21 ST_JNK_MAPK_PATHWAY 0 0
Category members Pathway Pathway_257 KEGG_GNRH_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_715 KEGG_MAPK_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0000165 MAPK cascade Database 0
Category members GO Category GO:0000187 activation of MAPK activity Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0071260 cellular response to mechanical stimulus Database 0


.

© Copyright Svejstrup Laboratory 2015