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cellular response to mechanical stimulus
(GO:0071260)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
GSK3B 2 1.020 -0.870 -1.128 1.091
CHEK1 2 -1.170 1.560
CHEK1 2 -1.170 1.560
BAK1 1 0.710 0.160 -0.419 2.039
CASP8 1 1.120 -1.090
BCL10 1 0.000 0.200
BAG3 1 0.180 -0.820
BAD 0 -0.660 1.190
ATP1A2 0 0.000 0.440 0.377 0.914 -1.883 0.083 0.031
FAS 0 1.380 -1.070
FAS 0 1.380 -1.070
MAP2K4 0 -0.300 0.320
TNFRSF1A 0 -0.590 0.470
MAP3K1 0 0.750 -1.270
MAPK3 0
CASP2 0 0.980 -1.120
NFKB1 0 0.720 -0.810
GADD45A 0 1.050 -0.170
TNFRSF10B 0 -0.030 -0.780
HABP4 0 -0.790 0.660
AKT1 0 -0.050 0.700
AKT1 0 0.860 -0.040
EGFR 0 -0.580 0.520 0.513 0.090
ITGB1 0 0.390 -0.650 0.101 -0.036
GJA1 0 -0.410 0.430
BMP6 0 1.970 -0.630
ATP1A1 0 0.410 -0.420 0.377 0.914 -1.883 0.083 0.031
CTNNB1 0 0.490 -0.230
CTNNB1 0 0.490 -0.230 -0.415 0.628 0.215
MAP3K2 0 -1.220 1.960
BNIP3 0 0.610 -0.650

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
AKT1 Phosphorylation S124 0.252 0.311 _SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1 Phosphorylation S126 -0.241 _SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1 Ubiquitylation K301 0.988 _EGIK(gl)DGATMK_
ATP1A1 Ubiquitylation K9 0.245 0.226 _DK(gl)YEPAAVSEQGDKK_
ATP1A1 Phosphorylation S16 -0.121 0.100 _DKYEPAAVS(ph)EQGDKK_
ATP1A1 Ubiquitylation K22 0.726 _DKYEPAAVSEQGDKK(gl)_
ATP1A1 Ubiquitylation K24 0.135 _YEPAAVSEQGDKKGK(gl)_
ATP1A1 Ubiquitylation K36 1.089 0.875 _DMDELK(gl)K_
ATP1A1 Ubiquitylation K37 1.220 _DMDELK(gl)KEVSMDDHK_
ATP1A1 Ubiquitylation K45 -0.107 _EVSMDDHK(gl)LSLDELHR_
ATP1A1 Ubiquitylation K54 -1.233 0.206 _K(gl)YGTDLSR_
ATP1A1 Ubiquitylation K156 -1.024 0.552 _SSK(gl)IMESFK_
ATP1A1 Ubiquitylation K162 -0.474 0.225 _IMESFK(gl)NMVPQQALVIR_
ATP1A1 Ubiquitylation K212 -0.693 -0.230 _IISANGCK(gl)VDNSSLTGESEPQTR_
ATP1A1 Ubiquitylation K377 -1.676 -0.190 _NLEAVETLGSTSTICSDK(gl)TGTLTQNR_
ATP1A1 Ubiquitylation K444 -0.592 -0.292 _AVFQANQENLPILK(gl)R_
ATP1A1 Ubiquitylation K468 -0.291 0.462 _CIELCCGSVK(gl)EMR_
ATP1A1 Ubiquitylation K476 1.195 _YAK(gl)IVEIPFNSTNK_
ATP1A1 Ubiquitylation K508 -1.151 _NPNTSEPQHLLVMK(gl)GAPER_
ATP1A1 Ubiquitylation K605 0.393 0.204 _AAVPDAVGK(gl)CR_
ATP1A1 Ubiquitylation K625 -2.291 -0.674 _VIMVTGDHPITAK(gl)AIAK_
ATP1A1 Ubiquitylation K629 0.204 _AIAK(gl)GVGIISEGNETVEDIAAR_
ATP1A1 Ubiquitylation K661 -1.060 -0.037 _DAK(gl)ACVVHGSDLK_
ATP1A1 Ubiquitylation K698 -1.846 -0.336 _TSPQQK(gl)LIIVEGCQR_
ATP1A1 Ubiquitylation K726 -1.405 -0.328 _QGAIVAVTGDGVNDSPALK(gl)K_
ATP1A1 Ubiquitylation K727 -1.257 -0.518 _QGAIVAVTGDGVNDSPALKK(gl)_
ATP1A1 Ubiquitylation K773 0.165 _LIFDNLK(gl)K_
ATP1A1 Ubiquitylation K840 -1.467 -0.964 _NPK(gl)TDKLVNER_
ATP1A1 Ubiquitylation K843 0.143 _TDK(gl)LVNER_
ATP1A1 Ubiquitylation K950 0.029 _NSVFQQGMK(gl)NK_
ATP1A1 Ubiquitylation K952 -1.917 0.295 _NSVFQQGMKNK(gl)_
ATP1A2 Ubiquitylation K9 0.245 0.226 _DK(gl)YEPAAVSEQGDKK_
ATP1A2 Phosphorylation S16 -0.121 0.100 _DKYEPAAVS(ph)EQGDKK_
ATP1A2 Ubiquitylation K22 0.726 _DKYEPAAVSEQGDKK(gl)_
ATP1A2 Ubiquitylation K24 0.135 _YEPAAVSEQGDKKGK(gl)_
ATP1A2 Ubiquitylation K36 1.089 0.875 _DMDELK(gl)K_
ATP1A2 Ubiquitylation K37 1.220 _DMDELK(gl)KEVSMDDHK_
ATP1A2 Ubiquitylation K45 -0.107 _EVSMDDHK(gl)LSLDELHR_
ATP1A2 Ubiquitylation K54 -1.233 0.206 _K(gl)YGTDLSR_
ATP1A2 Ubiquitylation K156 -1.024 0.552 _SSK(gl)IMESFK_
ATP1A2 Ubiquitylation K162 -0.474 0.225 _IMESFK(gl)NMVPQQALVIR_
ATP1A2 Ubiquitylation K212 -0.693 -0.230 _IISANGCK(gl)VDNSSLTGESEPQTR_
ATP1A2 Ubiquitylation K377 -1.676 -0.190 _NLEAVETLGSTSTICSDK(gl)TGTLTQNR_
ATP1A2 Ubiquitylation K444 -0.592 -0.292 _AVFQANQENLPILK(gl)R_
ATP1A2 Ubiquitylation K468 -0.291 0.462 _CIELCCGSVK(gl)EMR_
ATP1A2 Ubiquitylation K476 1.195 _YAK(gl)IVEIPFNSTNK_
ATP1A2 Ubiquitylation K508 -1.151 _NPNTSEPQHLLVMK(gl)GAPER_
ATP1A2 Ubiquitylation K605 0.393 0.204 _AAVPDAVGK(gl)CR_
ATP1A2 Ubiquitylation K625 -2.291 -0.674 _VIMVTGDHPITAK(gl)AIAK_
ATP1A2 Ubiquitylation K629 0.204 _AIAK(gl)GVGIISEGNETVEDIAAR_
ATP1A2 Ubiquitylation K661 -1.060 -0.037 _DAK(gl)ACVVHGSDLK_
ATP1A2 Ubiquitylation K698 -1.846 -0.336 _TSPQQK(gl)LIIVEGCQR_
ATP1A2 Ubiquitylation K726 -1.405 -0.328 _QGAIVAVTGDGVNDSPALK(gl)K_
ATP1A2 Ubiquitylation K727 -1.257 -0.518 _QGAIVAVTGDGVNDSPALKK(gl)_
ATP1A2 Ubiquitylation K773 0.165 _LIFDNLK(gl)K_
ATP1A2 Ubiquitylation K840 -1.467 -0.964 _NPK(gl)TDKLVNER_
ATP1A2 Ubiquitylation K843 0.143 _TDK(gl)LVNER_
ATP1A2 Ubiquitylation K950 0.029 _NSVFQQGMK(gl)NK_
ATP1A2 Ubiquitylation K952 -1.917 0.295 _NSVFQQGMKNK(gl)_
BAD Phosphorylation S74 -0.904 -0.452 _HS(ph)SYPAGTEDDEGM(ox)GEEPSPFR_
BAD Phosphorylation S75 -0.914 -0.660 _HSS(ph)YPAGTEDDEGMGEEPSPFR_
BAD Phosphorylation S97 0.056 _S(ph)RSAPPNLWAAQR_
BAD Phosphorylation S99 -0.299 0.161 _S(ph)APPNLWAAQR_
BAD Phosphorylation S118 1.277 1.089 _RM(ox)S(ph)DEFVDSFKK_
BAG3 Phosphorylation S173 -0.549 -0.580 _SQS(ph)PAASDCSSSSSSASLPSSGR_
BAG3 Phosphorylation S194 -0.402 -0.523 _S(ph)SLGSHQLPR_
BAG3 Phosphorylation S195 0.244 -0.933 _SS(ph)LGSHQLPR_
BAG3 Phosphorylation S289 4.691 -1.292 _SSTPLHS(ph)PSPIR_
BAG3 Phosphorylation S291 0.973 -1.061 _SSTPLHSPS(ph)PIR_
BAG3 Phosphorylation S377 -2.611 -2.836 _VPPAPVPCPPPS(ph)PGPSAVPSSPK_
BAG3 Phosphorylation S381 -1.826 _VPPAPVPCPPPSPGPS(ph)AVPS(ph)SPK_
BAG3 Phosphorylation S385 -3.389 -1.522 _VPPAPVPCPPPS(ph)PGPSAVPS(ph)SPK_
BAG3 Phosphorylation S386 -3.389 -3.269 _VPPAPVPCPPPS(ph)PGPSAVPSS(ph)PK_
BCL10 Phosphorylation S138 1.515 1.393 _SNS(ph)DESNFSEK_
BMP6 Ubiquitylation K409 -1.025 _VSSASDYNSSELK(gl)TACR_
BNIP3 Phosphorylation S136 0.383 0.514 _ASETDTHS(ph)IGEK_
BNIP3 Ubiquitylation K161 0.164 -0.368 _EVESILK(gl)K_
CASP2 Phosphorylation S340 -0.347 -1.529 _NHAGS(ph)PGCEESDAGKEK_
CASP8 Ubiquitylation K183 1.917 _IINDYEEFSK(gl)ER_
CASP8 Ubiquitylation K461 -2.031 _NMGK(gl)QMPQPTFTLR_
CHEK1 Ubiquitylation K53 0.879 _AVDCPENIK(gl)K_
CHEK1 Ubiquitylation K54 0.738 _AVDCPENIKK(gl)_
CHEK1 Phosphorylation S296 -0.098 0.184 _VTS(ph)GGVSESPSGFSK_
CHEK1 Phosphorylation S300 1.091 _VTSGGVS(ph)ESPSGFSK_
CHEK1 Phosphorylation S302 1.750 _VTSGGVSES(ph)PSGFSK_
CHEK1 Phosphorylation S317 1.903 _HIQSNLDFS(ph)PVNSASSEENVK_
CHEK1 Ubiquitylation K399 -0.582 _ETCEK(gl)LGYQWK_
CTNNB1 Ubiquitylation K158 -1.265 _AIPELTK(gl)LLNDEDQVVVNK_
CTNNB1 Ubiquitylation K180 -0.546 -0.636 _AAVM(ox)VHQLSK(gl)K_
CTNNB1 Ubiquitylation K181 -0.717 -0.729 _AAVMVHQLSKK(gl)_
CTNNB1 Phosphorylation S191 -0.024 0.129 _S(ph)PQMVSAIVR_
CTNNB1 Ubiquitylation K435 -0.350 _NK(gl)MM(ox)VCQVGGIEALVR_
CTNNB1 Ubiquitylation K496 -1.262 _LHYGLPVVVK(gl)_
CTNNB1 Phosphorylation S552 1.233 1.224 _RTS(ph)MGGTQQQFVEGVR_
CTNNB1 Phosphorylation T556 1.275 0.995 _RTSM(ox)GGT(ph)QQQFVEGVR_
CTNNB1 Ubiquitylation K671 -0.941 -0.934 _MSEDKPQDYK(gl)K_
EGFR Phosphorylation T693 0.486 -0.139 _ELVEPLT(ph)PSGEAPNQALLR_
EGFR Phosphorylation S991 -0.041 _MHLPS(ph)PTDSNFYR_
FAS Phosphorylation S236 -0.027 _ENQGS(ph)HESPTLNPETVAINLSDVDLSK_
FAS Phosphorylation S239 0.266 _ENQGSHES(ph)PTLNPETVAINLSDVDLSK_
FAS Ubiquitylation K343 1.126 _IQTIILK(gl)DITSDSENSNFR_
GADD45A Ubiquitylation K12 -0.515 0.281 _TLEEFSAGEQK(gl)TER_
GADD45A Ubiquitylation K29 0.092 _VGDALEEVLSK(gl)ALSQR_
GJA1 Ubiquitylation K109 0.099 _LNKK(gl)EEELK_
GJA1 Ubiquitylation K128 0.209 1.057 _VAQTDGVNVDMHLK(gl)QIEIK_
GJA1 Ubiquitylation K136 -0.888 _FK(gl)YGIEEHGK_
GJA1 Ubiquitylation K243 0.152 0.237 _GK(gl)SDPYHATSGALSPAK_
GJA1 Ubiquitylation K258 -0.280 0.063 _SDPYHATSGALSPAK(gl)DCGSQK_
GJA1 Ubiquitylation K303 -0.106 0.280 _NYNK(gl)QASEQNWANYSAEQNR_
GJA1 Ubiquitylation K345 -0.464 _MGQAGSTISNSHAQPFDFPDDNQNSK(gl)K_
GJA1 Ubiquitylation K346 -1.004 -0.300 _MGQAGSTISNSHAQPFDFPDDNQNSKK(gl)_
GJA1 Phosphorylation S364 -0.300 _LAAGHELQPLAIVDQRPS(ph)SR_
GJA1 Phosphorylation S365 -0.300 _LAAGHELQPLAIVDQRPS(ph)SR_
GJA1 Phosphorylation S372 0.940 1.430 _AS(ph)SRPRPDDLEI_
GJA1 Phosphorylation S373 0.664 0.467 _ASS(ph)RPRPDDLEI_
GSK3B Phosphorylation S9 -0.483 0.010 _TTS(ph)FAESCKPVQQPSAFGSMK_
GSK3B Ubiquitylation K85 -0.204 _LCDSGELVAIK(gl)K_
GSK3B Ubiquitylation K86 -0.204 _LCDSGELVAIK(gl)K_
GSK3B Phosphorylation S215 0.296 0.477 _GEPNVS(ph)YICSR_
GSK3B Phosphorylation Y216 0.356 0.376 _GEPNVSY(ph)ICSR_
GSK3B Phosphorylation T390 2.800 2.527 _IQAAAST(ph)PTNATAASDANTGDR_
HABP4 Phosphorylation S108 -1.547 -1.329 _SLPAPVAQRPDS(ph)PGGGLQAPGQK_
ITGB1 Ubiquitylation K774 0.402 _MNAK(gl)WDTGENPIYK_
ITGB1 Ubiquitylation K784 -0.172 0.350 _WDTGENPIYK(gl)SAVTTVVNPK_
ITGB1 Ubiquitylation K794 0.755 0.604 _SAVTTVVNPK(gl)YEGK_
MAP2K4 Phosphorylation S80 0.441 _LRTHS(ph)IESSGK_
MAP3K1 Phosphorylation S292 0.209 _RAPS(ph)PDGFSPYSPEETNR_
MAP3K1 Phosphorylation S506 1.427 _SHDFYSHELS(ph)SPVDSPSSLR_
MAP3K1 Phosphorylation S507 1.436 _SHDFYSHELSS(ph)PVDSPSSLR_
MAP3K1 Phosphorylation S923 0.127 -0.120 _LSAS(ph)SEDISER_
MAP3K2 Phosphorylation S153 0.506 -0.231 _RLS(ph)IIGPTSR_
MAP3K2 Phosphorylation S163 -0.910 -0.776 _DRS(ph)SPPPGYIPDELHQVAR_
MAP3K2 Phosphorylation S164 -0.743 -0.966 _DRS(ph)SPPPGYIPDELHQVAR_
MAP3K2 Phosphorylation S239 -0.284 -0.618 _AQS(ph)YPDNHQEFSDYDNPIFEK_
MAP3K2 Phosphorylation S331 0.008 _RRGS(ph)DIDNPTLTVM(ox)DISPPSR_
MAPK3 Phosphorylation Y204 -0.807 -2.487 _IADPEHDHTGFLTEY(ph)VATR_
MAPK3 Ubiquitylation K289 -0.608 _NYLQSLPSKTK(gl)_
NFKB1 Phosphorylation S907 -0.025 0.113 _TTSQAHSLPLS(ph)PASTR_
TNFRSF10B Ubiquitylation K369 -0.724 _KLGLMDNEIK(gl)VAK_
TNFRSF1A Ubiquitylation K242 -0.111 _SK(gl)LYSIVCGK_


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