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Query: BMP6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
BMP6 0 -1.025 1.970 -0.630

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
BMP6 Ubiquitylation K409 -1.025 _VSSASDYNSSELK(gl)TACR_

Background Information for BMP6:


Pubmed-BMP6 »
Uniprot-BMP6 »
Biogrid-BMP6 »
ProteomicsDB-BMP6 »

Tumorportal-BMP6 »
COSMIC-BMP6 »
GenomeRNAi-BMP6 »
Genecards-BMP6


Protein-protein Interactions for BMP6
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in BMP6
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Cystine-knot_cytokine IPR029034 0.52
Category members TGF-b_C IPR001839 0.35
Category members TGF-b_N IPR001111 0.17


Protein complexes (CORUM database) featuring BMP6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring BMP6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005615 extracellular space Database 4.72
Category members GO Category GO:0008083 growth factor activity Database 2.34
Category members GO Category GO:0006955 immune response Database 1.22
Category members GO Category GO:0005125 cytokine activity Database 1.06
Category members GO Category GO:0050679 positive regulation of epithelial cell proliferation Database 0.5
Category members GO Category GO:0006954 inflammatory response Database 0.49
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation Database 0.23
Category members GO Category GO:0030509 BMP signaling pathway Database 0.2
Category members GO Category GO:0032026 response to magnesium ion Database 0.15
Category members Pathway Pathway_893 KEGG_TGF_BETA_SIGNALING_PATHWAY 0 0.14
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0003323 type B pancreatic cell development Database 0.1
Category members GO Category GO:0030154 cell differentiation Database 0.06
Category members GO Category GO:0001958 endochondral ossification Database 0.04
Category members GO Category GO:0051384 response to glucocorticoid Database 0.04
Category members Pathway Pathway_1151 KEGG_HEDGEHOG_SIGNALING_PATHWAY 0 0.04
Category members Pathway Pathway_1133 PID_BMP_PATHWAY 0 0
Category members GO Category GO:0001501 skeletal system development Database 0
Category members GO Category GO:0001503 ossification Database 0
Category members GO Category GO:0001649 osteoblast differentiation Database 0
Category members GO Category GO:0001654 eye development Database 0
Category members GO Category GO:0001822 kidney development Database 0
Category members GO Category GO:0001938 positive regulation of endothelial cell proliferation Database 0
Category members GO Category GO:0010039 response to iron ion Database 0
Category members GO Category GO:0014823 response to activity Database 0
Category members GO Category GO:0030501 positive regulation of bone mineralization Database 0
Category members GO Category GO:0030539 male genitalia development Database 0
Category members GO Category GO:0031988 membrane-bounded vesicle Database 0
Category members GO Category GO:0032332 positive regulation of chondrocyte differentiation Database 0
Category members GO Category GO:0032349 positive regulation of aldosterone biosynthetic process Database 0
Category members GO Category GO:0032526 response to retinoic acid Database 0
Category members GO Category GO:0040007 growth Database 0
Category members GO Category GO:0045603 positive regulation of endothelial cell differentiation Database 0
Category members GO Category GO:0045666 positive regulation of neuron differentiation Database 0
Category members GO Category GO:0045669 positive regulation of osteoblast differentiation Database 0
Category members GO Category GO:0050714 positive regulation of protein secretion Database 0
Category members GO Category GO:0051216 cartilage development Database 0
Category members GO Category GO:0060395 SMAD protein signal transduction Database 0
Category members GO Category GO:0070700 BMP receptor binding Database 0
Category members GO Category GO:0071260 cellular response to mechanical stimulus Database 0


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