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Results for the Category
KEGG_TGF_BETA_SIGNALING_PATHWAY
(Pathway_893)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
ZFYVE16 1 -1.080 1.970
CUL1 1 0.630 -0.610 -0.314 0.662 2.069 0.342 0.118
RBL1 1 0.270 -0.950
PPP2CB 1 2.210 -0.980 0.194 0.044 0.215
PPP2CB 1 2.210 -0.980 0.650 1.189
PPP2R1A 1 -0.260 -0.200 0.714 0.973
PPP2R1A 1 -0.260 -0.200 -0.003 -0.196 0.057
PPP2R1A 1 -0.260 -0.200 1.697 1.450 -1.553
PPP2R1B 1 1.240 -0.730 1.697 1.450 -1.553
CREBBP 0 0.840 -0.950 -3.889 -1.071
RHOA 0 -0.510 1.370 -0.485 0.532 0.279
ROCK1 0 -1.420 2.380 -0.112 -0.732
RBX1 0 0.920 -0.940 -0.015 -0.422
EP300 0 -1.210 1.320 -1.089 -1.694 -0.723
BMP7 0
MAPK3 0
RBL2 0 0.890 -0.800
TGFB1 0 -0.550 1.050
TGFBR1 0 -0.260 0.020
BMPR1A 0 0.020 -0.130
RPS6KB1 0 0.850 -0.600
SKP1 0 1.470 -0.970 -1.305 -0.243 -0.093 0.054
SKP1 0 1.470 -0.970 -0.472
PPP2CA 0 0.160 -0.540 0.194 0.044 0.215
PPP2CA 0 0.160 -0.540 0.650 1.189
SMAD5 0 0.640 -0.430
ID2 0 -0.080 -0.630
TGFB3 0 0.900 -0.540
ROCK2 0 -1.660 2.330
MYC 0 0.170 0.550 -2.443 -0.949 -0.454 -1.290
BMPR1B 0 -0.810 0.900
SMAD4 0 0.420 -0.390 0.020 0.556 -0.485
BMP6 0 1.970 -0.630
ZFYVE9 0 -0.930 0.760
SMAD3 0 -1.560 1.800
SMAD3 0 0.270 -0.340
ID4 0 0.670 -0.690
SMAD2 0
RPS6KB2 0 -1.260 2.030
SP1 0 0.404 0.333 0.650
TFDP1 0 -0.430 0.060 -1.111 0.446 -1.279 -0.496
E2F4 0 0.930 -0.810

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
BMP6 Ubiquitylation K409 -1.025 _VSSASDYNSSELK(gl)TACR_
BMP7 Ubiquitylation K178 -0.107 _IYK(gl)DYIR_
BMPR1A Ubiquitylation K232 -0.391 0.172 _TIAK(gl)QIQMVR_
BMPR1A Ubiquitylation K477 0.265 -0.134 _EVVCVK(gl)R_
BMPR1B Ubiquitylation K477 1.033 _EIVCIK(gl)K_
CREBBP Phosphorylation S2093 0.037 0.097 _SIS(ph)PSALQDLLR_
CUL1 Ubiquitylation K262 0.119 _ESTEFLQQNPVTEYMK(gl)K_
CUL1 Ubiquitylation K263 0.119 -0.055 _ESTEFLQQNPVTEYMK(gl)K_
CUL1 Ubiquitylation K410 0.250 0.326 _FINNNAVTK(gl)MAQSSSK_
CUL1 Ubiquitylation K417 0.761 _MAQSSSK(gl)SPELLAR_
CUL1 Ubiquitylation K468 1.237 _FYAK(gl)MLAK_
CUL1 Ubiquitylation K503 0.665 _QACGFEYTSK(gl)LQR_
CUL1 Ubiquitylation K769 0.292 _VDGEK(gl)DTYSYLA_
E2F4 Phosphorylation T14 -2.100 _(ac)AEAGPQAPPPPGT(ph)PSR_
E2F4 Phosphorylation S16 -2.158 -1.655 _(ac)AEAGPQAPPPPGTPS(ph)R_
EP300 Phosphorylation S1038 -0.672 -0.349 _TEIKEEEDQPSTSATQSS(ph)PAPGQSK_
EP300 Phosphorylation S1726 0.994 0.627 _LGLGLDDESNNQQAAATQS(ph)PGDSRR_
EP300 Phosphorylation S2328 -1.092 0.725 _PQSQPPHSSPS(ph)PR_
ID2 Phosphorylation S14 -0.139 _NS(ph)LSDHSLGISR_
ID4 Phosphorylation S5 -0.437 -0.234 _AVS(ph)PVRPSGR_
MAPK3 Phosphorylation Y204 -0.807 -2.487 _IADPEHDHTGFLTEY(ph)VATR_
MAPK3 Ubiquitylation K289 -0.608 _NYLQSLPSKTK(gl)_
MYC Phosphorylation S20 -1.444 -1.145 _PLNVS(ph)FTNR_
MYC Phosphorylation T72 -1.699 -1.813 _FELLPT(ph)PPLS(ph)PSRR_
MYC Phosphorylation S76 -1.777 -1.435 _FELLPTPPLS(ph)PSR_
MYC Phosphorylation S81 0.459 _S(ph)GLCSPSYVAVTPFSLR_
MYC Phosphorylation S85 0.199 0.073 _SGLCS(ph)PSYVAVTPFSLR_
MYC Ubiquitylation K162 -2.475 -1.259 _LVSEK(gl)LASYQAAR_
MYC Phosphorylation S295 -0.903 _SESGS(ph)PSAGGHSKPPHSPLVLK_
MYC Phosphorylation S307 -1.486 _SES(ph)GSPSAGGHSKPPHS(ph)PLVLK_
MYC Ubiquitylation K340 -2.449 _VK(gl)LDSVR_
MYC Ubiquitylation K403 -3.432 _DQIPELENNEK(gl)APK_
PPP2CA Ubiquitylation K4 -0.788 -0.378 _(ac)MDDK(gl)AFTK_
PPP2CA Ubiquitylation K4 -0.450 -0.016 _(ac)M(ox)DEK(gl)VFTK_
PPP2CA Ubiquitylation K8 -0.522 _VFTK(gl)ELDQWIEQLNECK_
PPP2CA Ubiquitylation K21 -1.370 _ELDQWVEQLNECK(gl)QLNENQVR_
PPP2CA Ubiquitylation K21 -1.106 _ELDQWIEQLNECK(gl)QLSESQVK_
PPP2CA Ubiquitylation K29 0.211 0.122 _QLSESQVK(gl)SLCEK_
PPP2CA Ubiquitylation K36 -0.455 0.187 _AK(gl)EILTK_
PPP2CA Ubiquitylation K36 -0.455 0.187 _AK(gl)EILTK_
PPP2CA Ubiquitylation K41 -0.049 0.003 _EILTK(gl)ESNVQEVR_
PPP2CA Ubiquitylation K74 -0.316 -0.316 _IGGK(gl)SPDTNYLFMGDYVDR_
PPP2CB Ubiquitylation K4 -0.788 -0.378 _(ac)MDDK(gl)AFTK_
PPP2CB Ubiquitylation K4 -0.450 -0.016 _(ac)M(ox)DEK(gl)VFTK_
PPP2CB Ubiquitylation K8 -0.522 _VFTK(gl)ELDQWIEQLNECK_
PPP2CB Ubiquitylation K21 -1.370 _ELDQWVEQLNECK(gl)QLNENQVR_
PPP2CB Ubiquitylation K21 -1.106 _ELDQWIEQLNECK(gl)QLSESQVK_
PPP2CB Ubiquitylation K29 0.211 0.122 _QLSESQVK(gl)SLCEK_
PPP2CB Ubiquitylation K36 -0.455 0.187 _AK(gl)EILTK_
PPP2CB Ubiquitylation K36 -0.455 0.187 _AK(gl)EILTK_
PPP2CB Ubiquitylation K41 -0.049 0.003 _EILTK(gl)ESNVQEVR_
PPP2CB Ubiquitylation K74 -0.316 -0.316 _IGGK(gl)SPDTNYLFMGDYVDR_
PPP2R1A Ubiquitylation K34 0.304 _K(gl)LSTIALALGVER_
PPP2R1A Ubiquitylation K107 0.584 0.441 _DK(gl)AVESLR_
PPP2R1A Ubiquitylation K163 0.106 0.149 _VSSAVK(gl)AELR_
PPP2R1A Ubiquitylation K175 -0.351 _ASNAVK(gl)AEIR_
PPP2R1A Ubiquitylation K188 0.395 0.130 _AAASK(gl)LGEFAK_
PPP2R1A Ubiquitylation K255 0.301 0.202 _QAAEDK(gl)SWR_
PPP2R1A Ubiquitylation K266 0.464 0.338 _YMVADK(gl)FTELQK_
PPP2R1A Ubiquitylation K284 -0.575 _FSELQK(gl)AMGPK_
PPP2R1A Ubiquitylation K307 0.224 0.500 _VK(gl)EFCENLSADCR_
PPP2R1A Ubiquitylation K467 0.890 _EAATSNLK(gl)K_
PPP2R1A Ubiquitylation K468 0.890 _EAATSNLK(gl)K_
PPP2R1A Ubiquitylation K542 -0.187 _FNVAK(gl)SLQK_
PPP2R1B Ubiquitylation K175 -0.351 _ASNAVK(gl)AEIR_
PPP2R1B Ubiquitylation K284 -0.575 _FSELQK(gl)AMGPK_
RBL1 Phosphorylation S640 -0.916 -1.810 _DMQPLS(ph)PISVHER_
RBL1 Phosphorylation S749 0.935 1.566 _VKS(ph)PVSLTAHSLIGASPK_
RBL1 Ubiquitylation K885 -0.844 _SVLLK(gl)SIPR_
RBL2 Phosphorylation S639 0.520 _ADEICIAGS(ph)PLTPR_
RBL2 Phosphorylation S662 0.551 0.137 _SITS(ph)PTTLYDR_
RBL2 Phosphorylation S981 -1.828 _SSSTLPVPQPS(ph)SAPPT(ph)PTR_
RBL2 Phosphorylation S982 -2.152 _SSSTLPVPQPSS(ph)APPT(ph)PTR_
RBL2 Phosphorylation T986 -1.219 -1.828 _SSSTLPVPQPSS(ph)APPT(ph)PTR_
RBL2 Phosphorylation S1078 0.241 0.286 _IFYYFS(ph)NSPSK_
RBL2 Phosphorylation S1080 -0.327 -0.297 _IFYYFSNS(ph)PSK_
RBL2 Phosphorylation S1112 -0.598 -0.843 _RGILLEDGSES(ph)PAKR_
RBX1 Phosphorylation T9 -0.553 _(ac)AAAMDVDT(ph)PSGTNSGAGK_
RBX1 Ubiquitylation K19 -0.376 -0.371 _(ac)AAAMDVDTPSGTNSGAGK(gl)KR_
RBX1 Ubiquitylation K20 -0.541 -0.371 _(ac)AAAMDVDTPSGTNSGAGKK(gl)R_
RHOA Ubiquitylation K6 0.708 _K(gl)KLVIVGDGACGK_
RHOA Ubiquitylation K7 0.708 _K(gl)KLVIVGDGACGK_
RHOA Ubiquitylation K118 -0.408 _HFCPNVPIILVGNK(gl)K_
RHOA Ubiquitylation K119 -0.408 _HFCPNVPIILVGNK(gl)K_
RHOA Ubiquitylation K135 -0.528 -0.796 _MK(gl)QEPVKPEEGRDMANR_
RHOA Ubiquitylation K162 0.345 0.453 _IGAFGYMECSAK(gl)TK_
ROCK1 Phosphorylation S1105 -0.245 -0.845 _LLDLSDSTSVAS(ph)FPSADETDGNLPESR_
ROCK2 Ubiquitylation K1222 -0.679 _ADAK(gl)EIPR_
RPS6KB1 Ubiquitylation K99 -0.316 _VLGK(gl)GGYGK_
RPS6KB1 Phosphorylation S447 -0.525 -0.458 _TPVS(ph)PVKFSPGDFWGR_
RPS6KB2 Ubiquitylation K99 -0.316 _VLGK(gl)GGYGK_
SKP1 Ubiquitylation K130 0.138 0.140 _GK(gl)TPEEIRK_
SKP1 Phosphorylation T131 -0.024 -0.138 _GKT(ph)PEEIRK_
SKP1 Ubiquitylation K142 0.165 0.894 _TFNIK(gl)NDFTEEEEAQVRK_
SKP1 Ubiquitylation K155 -0.096 0.069 _K(gl)ENQWCEEK_
SKP1 Ubiquitylation K163 0.109 -0.020 _ENQWCEEK(gl)_
SMAD2 Phosphorylation T8 -0.896 -0.885 _(ac)SSILPFT(ph)PPVVK_
SMAD2 Ubiquitylation K13 -0.058 _(ac)SSILPFTPPVVK(gl)R_
SMAD3 Ubiquitylation K13 -0.704 _(ac)SSILPFTPPIVK(gl)R_
SMAD5 Ubiquitylation K64 -2.082 -1.647 _ALSSPGQPSK(gl)CVTIPR_
SP1 Phosphorylation S2 0.834 1.114 _(ac)S(ph)DQDHSMDEMTAVVK_
SP1 Phosphorylation S7 0.586 0.217 _(ac)SDQDHS(ph)MDEMTAVVK_
SP1 Phosphorylation S56 -0.154 _SSSTGSSSSTGGGGQES(ph)QPSPLALLAATCSR_
SP1 Phosphorylation S59 -0.217 -0.135 _SSSTGSSSSTGGGGQESQPS(ph)PLALLAATCSR_
TFDP1 Phosphorylation S23 -0.667 -0.353 _VFIDQNLS(ph)PGK_
TFDP1 Ubiquitylation K320 -0.549 0.052 _MGMACGLESGSCSAEDLK(gl)MAR_
TGFB1 Ubiquitylation K50 -0.557 _GQILSK(gl)LR_
TGFB3 Ubiquitylation K50 -0.557 _GQILSK(gl)LR_
TGFBR1 Ubiquitylation K449 -0.991 _VVCEQK(gl)LRPNIPNR_
TGFBR1 Ubiquitylation K502 0.553 0.430 _TLSQLSQQEGIK(gl)M_
ZFYVE16 Ubiquitylation K86 -0.638 _TLK(gl)GLTSIQNEK_
ZFYVE16 Ubiquitylation K455 -1.793 _K(gl)IDPDQTVIR_
ZFYVE16 Phosphorylation S939 1.491 1.197 _NEIIQS(ph)PISQVPSVEK_
ZFYVE16 Ubiquitylation K1202 -2.966 3.670 _LGAEYK(gl)AYPAPLTSIR_
ZFYVE16 Ubiquitylation K1257 0.166 0.179 _SCIK(gl)IPR_
ZFYVE16 Ubiquitylation K1364 -0.812 _LALREQK(gl)DFK_
ZFYVE16 Ubiquitylation K1367 -1.498 _DFK(gl)ITCGK_
ZFYVE16 Ubiquitylation K1372 0.291 _ITCGK(gl)VDAVDLR_
ZFYVE9 Ubiquitylation K543 1.139 _GNEATEGSGLLLNSTGDLMK(gl)K_
ZFYVE9 Ubiquitylation K544 1.139 _GNEATEGSGLLLNSTGDLMK(gl)K_
ZFYVE9 Ubiquitylation K622 0.886 _NKNDILGKAK(gl)_


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