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Query: RBL1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RBL1 1 1.657 0.270 -0.950

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RBL1 Phosphorylation S749 0.935 1.566 _VKS(ph)PVSLTAHSLIGASPK_
RBL1 Ubiquitylation K885 -0.844 _SVLLK(gl)SIPR_
RBL1 Phosphorylation S640 -0.916 -1.810 _DMQPLS(ph)PISVHER_

Background Information for RBL1:


Pubmed-RBL1 »
Uniprot-RBL1 »
Biogrid-RBL1 »
ProteomicsDB-RBL1 »

Tumorportal-RBL1 »
COSMIC-RBL1 »
GenomeRNAi-RBL1 »
Genecards-RBL1


Protein-protein Interactions for RBL1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C3orf62 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCNA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CTBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TXNDC11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RBL1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RB_B IPR002719 0.21
Category members RB_A IPR002720 0.21
Category members RB_N IPR024599 0.21
Category members RB_C IPR015030 0.05
Category members Cyclin-like IPR013763 0


Protein complexes (CORUM database) featuring RBL1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5614 Emerin complex 32 Database 1.48
Category members Corum 5159 E2F4-p107-cyclinE complex Database 0.02
Category members Corum 5589 LINC complex, S-phase Database 0.01
Category members Corum 1474 SMAD3/4-E2F4/5-p107-DP1 complex Database 0
Category members Corum 1661 E2F4-p107-cyclinA complex Database 0
Category members Corum 2975 SMAD3-E2F4/5-p107-DP1 complex Database 0
Category members Corum 5144 E2F1-p107-cyclinA complex Database 0
Category members Corum 5609 Emerin regulatory complex Database 0


Categories featuring RBL1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members Pathway Pathway_866 KEGG_CELL_CYCLE 0 2.13
Category members Pathway Pathway_313 REACTOME_MITOTIC_G1_G1_S_PHASES 0 1.45
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members Pathway Pathway_777 REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX 0 0.89
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members Pathway Pathway_325 PID_E2F_PATHWAY 0 0.62
Category members Pathway Pathway_845 PID_SMAD2_3NUCLEAR_PATHWAY 0 0.46
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0006367 transcription initiation from RNA polymerase II promoter Database 0.25
Category members GO Category GO:0007179 transforming growth factor beta receptor signaling pathway Database 0.25
Category members GO Category GO:0043550 regulation of lipid kinase activity Database 0.21
Category members Pathway Pathway_142 PID_MYC_REPRESS_PATHWAY 0 0.21
Category members GO Category GO:0005667 transcription factor complex Database 0.19
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0016568 chromatin modification Database 0.18
Category members Pathway Pathway_802 REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER 0 0.17
Category members Pathway Pathway_893 KEGG_TGF_BETA_SIGNALING_PATHWAY 0 0.14
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0051726 regulation of cell cycle Database 0.11
Category members Pathway Pathway_822 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY 0 0.09
Category members Pathway Pathway_808 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION 0 0.08
Category members Pathway Pathway_791 REACTOME_G1_PHASE 0 0.02
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members Pathway Pathway_1097 BIOCARTA_ETS_PATHWAY 0 0
Category members Pathway Pathway_869 REACTOME_G0_AND_EARLY_G1 0 0
Category members Pathway Pathway_970 BIOCARTA_CELLCYCLE_PATHWAY 0 0


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