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REACTOME_G1_PHASE
(Pathway_791)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
RPS27A 4 -1.330 2.560 -0.309 0.131 -0.009
UBA52 3 -1.260 2.180 -0.309 0.131 -0.009
UBA52 3 -1.260 2.180
CUL1 1 0.630 -0.610 -0.314 0.662 2.069 0.342 0.118
RBL1 1 0.270 -0.950
PPP2CB 1 2.210 -0.980 0.194 0.044 0.215
PPP2CB 1 2.210 -0.980 0.650 1.189
PPP2R1A 1 -0.260 -0.200 0.714 0.973
PPP2R1A 1 -0.260 -0.200 -0.003 -0.196 0.057
PPP2R1A 1 -0.260 -0.200 1.697 1.450 -1.553
PPP2R1B 1 1.240 -0.730 1.697 1.450 -1.553
CCND1 1 -1.820 3.470
CCND2 1 1.210 -0.610
E2F2 0 0.670 -1.180
MNAT1 0 -0.030 -0.100 0.666
RBL2 0 0.890 -0.800
CDK6 0 -0.190 0.160
CDK6 0 -0.190 0.160 -0.510 0.013
E2F3 0 0.000 0.020
SKP1 0 1.470 -0.970 -1.305 -0.243 -0.093 0.054
SKP1 0 1.470 -0.970 -0.472
PPP2CA 0 0.160 -0.540 0.194 0.044 0.215
PPP2CA 0 0.160 -0.540 0.650 1.189
CDKN1A 0 1.080 -0.750
CCNH 0 1.480 -0.550
CDK4 0 1.930 -0.950
CDK4 0 1.930 -0.950 -0.510 0.013
RB1 0 1.180 -1.070 0.429 0.755
RB1 0 1.180 -1.070
SKP2 0 0.030 0.690
SKP2 0 0.030 0.690
CDKN2A 0 -0.080 -0.260 -0.556 -1.080 -3.270 -1.110
CKS1B 0 -0.980 1.540
TFDP1 0 -0.430 0.060 -1.111 0.446 -1.279 -0.496
E2F4 0 0.930 -0.810

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CCND1 Ubiquitylation K33 -0.490 _AMLK(gl)AEETCAPSVSYFK_
CCND1 Ubiquitylation K46 -1.016 -0.036 _AEETCAPSVSYFK(gl)CVQK_
CCND1 Ubiquitylation K95 -0.733 -0.137 _FLSLEPVK(gl)K_
CCND1 Ubiquitylation K96 -0.846 -0.155 _FLSLEPVKK(gl)_
CCND1 Ubiquitylation K238 0.245 _VIK(gl)CDPDCLR_
CCND2 Ubiquitylation K45 -0.759 -0.277 _YLPQCSYFK(gl)CVQK_
CCND2 Ubiquitylation K49 -0.524 _CVQK(gl)DIQPYMR_
CCND2 Ubiquitylation K113 -0.572 _LK(gl)ETSPLTAEK_
CCND2 Ubiquitylation K173 -1.137 0.202 _EK(gl)LSLIR_
CCND2 Phosphorylation S269 0.049 _DGS(ph)KSEDELDQASTPTDVR_
CCND2 Phosphorylation S271 2.155 _DGSKS(ph)EDELDQASTPTDVR_
CCNH Ubiquitylation K189 0.418 _K(gl)TADDFLNR_
CDK4 Ubiquitylation K142 -0.552 _DLK(gl)PENILVTSGGTVK_
CDK4 Ubiquitylation K211 -0.101 _K(gl)PLFCGNSEADQLGK_
CDK4 Phosphorylation S236 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK4 Phosphorylation S249 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK4 Ubiquitylation K297 0.247 0.052 _ALQHSYLHK(gl)DEGNPE_
CDK4 Phosphorylation S385 0.649 _HSSIS(ph)PVRLPLNSSLGAELSR_
CDK4 Phosphorylation S420 0.004 -0.202 _ES(ph)KGSPVFLPR_
CDK4 Phosphorylation S423 -0.155 -0.297 _GS(ph)PVFLPR_
CDK4 Phosphorylation T514 0.364 0.570 _DSKPIALKEEIVT(ph)PK_
CDK4 Phosphorylation S681 -2.532 -2.051 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK4 Phosphorylation S685 -2.729 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK4 Phosphorylation T692 -0.765 -1.849 _AIT(ph)PPQQPYK_
CDK4 Phosphorylation S1082 -1.661 -0.980 _KETTSGTSTEPVKNS(ph)SPAPPQPAPGK_
CDK4 Phosphorylation S1083 -1.093 -1.330 _NSS(ph)PAPPQPAPGK_
CDK4 Phosphorylation T1244 -0.956 _RT(ph)PTMPQEEAAACPPHILPPEK_
CDK6 Ubiquitylation K3 0.121 0.039 _(ac)MEK(gl)DGLCR_
CDK6 Phosphorylation S236 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK6 Phosphorylation S249 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK6 Phosphorylation S385 0.649 _HSSIS(ph)PVRLPLNSSLGAELSR_
CDK6 Phosphorylation S420 0.004 -0.202 _ES(ph)KGSPVFLPR_
CDK6 Phosphorylation S423 -0.155 -0.297 _GS(ph)PVFLPR_
CDK6 Phosphorylation T514 0.364 0.570 _DSKPIALKEEIVT(ph)PK_
CDK6 Phosphorylation S681 -2.532 -2.051 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK6 Phosphorylation S685 -2.729 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK6 Phosphorylation T692 -0.765 -1.849 _AIT(ph)PPQQPYK_
CDK6 Phosphorylation S1082 -1.661 -0.980 _KETTSGTSTEPVKNS(ph)SPAPPQPAPGK_
CDK6 Phosphorylation S1083 -1.093 -1.330 _NSS(ph)PAPPQPAPGK_
CDK6 Phosphorylation T1244 -0.956 _RT(ph)PTMPQEEAAACPPHILPPEK_
CDKN1A Ubiquitylation K188 -2.505 -1.077 _QTSMTDFYHSK(gl)R_
CKS1B Ubiquitylation K30 -0.426 -0.991 _DIAK(gl)LVPK_
CUL1 Ubiquitylation K262 0.119 _ESTEFLQQNPVTEYMK(gl)K_
CUL1 Ubiquitylation K263 0.119 -0.055 _ESTEFLQQNPVTEYMK(gl)K_
CUL1 Ubiquitylation K410 0.250 0.326 _FINNNAVTK(gl)MAQSSSK_
CUL1 Ubiquitylation K417 0.761 _MAQSSSK(gl)SPELLAR_
CUL1 Ubiquitylation K468 1.237 _FYAK(gl)MLAK_
CUL1 Ubiquitylation K503 0.665 _QACGFEYTSK(gl)LQR_
CUL1 Ubiquitylation K769 0.292 _VDGEK(gl)DTYSYLA_
E2F2 Ubiquitylation K188 -0.267 _TRYDTSLGLLTK(gl)K_
E2F2 Ubiquitylation K189 -0.267 _TRYDTSLGLLTK(gl)K_
E2F3 Ubiquitylation K188 -0.267 _TRYDTSLGLLTK(gl)K_
E2F3 Ubiquitylation K189 -0.267 _TRYDTSLGLLTK(gl)K_
E2F4 Phosphorylation T14 -2.100 _(ac)AEAGPQAPPPPGT(ph)PSR_
E2F4 Phosphorylation S16 -2.158 -1.655 _(ac)AEAGPQAPPPPGTPS(ph)R_
MNAT1 Phosphorylation S279 0.003 0.225 _AAS(ph)PQDLAGGYTSSLACHR_
PPP2CA Ubiquitylation K4 -0.788 -0.378 _(ac)MDDK(gl)AFTK_
PPP2CA Ubiquitylation K4 -0.450 -0.016 _(ac)M(ox)DEK(gl)VFTK_
PPP2CA Ubiquitylation K8 -0.522 _VFTK(gl)ELDQWIEQLNECK_
PPP2CA Ubiquitylation K21 -1.370 _ELDQWVEQLNECK(gl)QLNENQVR_
PPP2CA Ubiquitylation K21 -1.106 _ELDQWIEQLNECK(gl)QLSESQVK_
PPP2CA Ubiquitylation K29 0.211 0.122 _QLSESQVK(gl)SLCEK_
PPP2CA Ubiquitylation K36 -0.455 0.187 _AK(gl)EILTK_
PPP2CA Ubiquitylation K36 -0.455 0.187 _AK(gl)EILTK_
PPP2CA Ubiquitylation K41 -0.049 0.003 _EILTK(gl)ESNVQEVR_
PPP2CA Ubiquitylation K74 -0.316 -0.316 _IGGK(gl)SPDTNYLFMGDYVDR_
PPP2CB Ubiquitylation K4 -0.788 -0.378 _(ac)MDDK(gl)AFTK_
PPP2CB Ubiquitylation K4 -0.450 -0.016 _(ac)M(ox)DEK(gl)VFTK_
PPP2CB Ubiquitylation K8 -0.522 _VFTK(gl)ELDQWIEQLNECK_
PPP2CB Ubiquitylation K21 -1.370 _ELDQWVEQLNECK(gl)QLNENQVR_
PPP2CB Ubiquitylation K21 -1.106 _ELDQWIEQLNECK(gl)QLSESQVK_
PPP2CB Ubiquitylation K29 0.211 0.122 _QLSESQVK(gl)SLCEK_
PPP2CB Ubiquitylation K36 -0.455 0.187 _AK(gl)EILTK_
PPP2CB Ubiquitylation K36 -0.455 0.187 _AK(gl)EILTK_
PPP2CB Ubiquitylation K41 -0.049 0.003 _EILTK(gl)ESNVQEVR_
PPP2CB Ubiquitylation K74 -0.316 -0.316 _IGGK(gl)SPDTNYLFMGDYVDR_
PPP2R1A Ubiquitylation K34 0.304 _K(gl)LSTIALALGVER_
PPP2R1A Ubiquitylation K107 0.584 0.441 _DK(gl)AVESLR_
PPP2R1A Ubiquitylation K163 0.106 0.149 _VSSAVK(gl)AELR_
PPP2R1A Ubiquitylation K175 -0.351 _ASNAVK(gl)AEIR_
PPP2R1A Ubiquitylation K188 0.395 0.130 _AAASK(gl)LGEFAK_
PPP2R1A Ubiquitylation K255 0.301 0.202 _QAAEDK(gl)SWR_
PPP2R1A Ubiquitylation K266 0.464 0.338 _YMVADK(gl)FTELQK_
PPP2R1A Ubiquitylation K284 -0.575 _FSELQK(gl)AMGPK_
PPP2R1A Ubiquitylation K307 0.224 0.500 _VK(gl)EFCENLSADCR_
PPP2R1A Ubiquitylation K467 0.890 _EAATSNLK(gl)K_
PPP2R1A Ubiquitylation K468 0.890 _EAATSNLK(gl)K_
PPP2R1A Ubiquitylation K542 -0.187 _FNVAK(gl)SLQK_
PPP2R1B Ubiquitylation K175 -0.351 _ASNAVK(gl)AEIR_
PPP2R1B Ubiquitylation K284 -0.575 _FSELQK(gl)AMGPK_
RB1 Phosphorylation S69 -3.602 -3.397 _TAATAAAAAAEPPAPPPPPPPEEDPEQDS(ph)GPEDLPLVR_
RB1 Ubiquitylation K97 -0.546 _LK(gl)IPDHVR_
RB1 Phosphorylation T388 0.005 0.116 _TLQTDSIDSFETQRT(ph)PR_
RB1 Phosphorylation T405 -0.851 -0.901 _KSNLDEEVNVIPPHT(ph)PVR_
RB1 Phosphorylation S820 -0.019 _S(ph)PYKFPSSPLR_
RB1 Ubiquitylation K823 -2.214 _SPYK(gl)FPSSPLR_
RB1 Phosphorylation S827 0.824 0.111 _FPSS(ph)PLR_
RB1 Phosphorylation S839 -0.701 -1.045 _IPGGNIYIS(ph)PLKS(ph)PYK_
RB1 Ubiquitylation K842 -0.751 _IPGGNIYISPLK(gl)SPYK_
RB1 Phosphorylation S843 -0.701 -0.022 _IPGGNIYIS(ph)PLKS(ph)PYK_
RB1 Ubiquitylation K846 -2.084 _SPYK(gl)ISEGLPTPTK_
RB1 Phosphorylation T853 0.039 -0.555 _ISEGLPT(ph)PTKM(ox)T(ph)PR_
RB1 Ubiquitylation K856 -1.350 _ISEGLPTPTK(gl)MTPR_
RB1 Phosphorylation T858 -0.782 0.564 _ISEGLPT(ph)PTKMT(ph)PR_
RB1 Ubiquitylation K879 -0.187 _FQK(gl)INQMVCNSDR_
RBL1 Phosphorylation S640 -0.916 -1.810 _DMQPLS(ph)PISVHER_
RBL1 Phosphorylation S749 0.935 1.566 _VKS(ph)PVSLTAHSLIGASPK_
RBL1 Ubiquitylation K885 -0.844 _SVLLK(gl)SIPR_
RBL2 Phosphorylation S639 0.520 _ADEICIAGS(ph)PLTPR_
RBL2 Phosphorylation S662 0.551 0.137 _SITS(ph)PTTLYDR_
RBL2 Phosphorylation S981 -1.828 _SSSTLPVPQPS(ph)SAPPT(ph)PTR_
RBL2 Phosphorylation S982 -2.152 _SSSTLPVPQPSS(ph)APPT(ph)PTR_
RBL2 Phosphorylation T986 -1.219 -1.828 _SSSTLPVPQPSS(ph)APPT(ph)PTR_
RBL2 Phosphorylation S1078 0.241 0.286 _IFYYFS(ph)NSPSK_
RBL2 Phosphorylation S1080 -0.327 -0.297 _IFYYFSNS(ph)PSK_
RBL2 Phosphorylation S1112 -0.598 -0.843 _RGILLEDGSES(ph)PAKR_
RPS27A Ubiquitylation K6 1.066 0.995 _MQIFVK(gl)TLTGK_
RPS27A Ubiquitylation K11 -0.488 -0.081 _TLTGK(gl)TITLEVEPSDTIENVKAK(gl)_
RPS27A Ubiquitylation K27 -0.882 -0.159 _TLTGK(gl)TITLEVEPSDTIENVK(gl)AK_
RPS27A Ubiquitylation K29 -1.087 -1.029 _AK(gl)IQDK(gl)EGIPPDQQR_
RPS27A Ubiquitylation K33 -0.736 -0.407 _IQDK(gl)EGIPPDQQR_
RPS27A Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
RPS27A Phosphorylation S57 1.909 0.548 _TLS(ph)DYNIQK_
RPS27A Ubiquitylation K63 0.276 0.299 _TLSDYNIQK(gl)ESTLHLVLR_
RPS27A Ubiquitylation K99 0.109 2.111 _VK(gl)LAVLK_
RPS27A Ubiquitylation K104 0.674 2.102 _LAVLK(gl)YYK_
RPS27A Ubiquitylation K107 2.949 3.611 _YYK(gl)VDENGK(gl)ISR_
RPS27A Ubiquitylation K113 1.572 3.672 _YYK(gl)VDENGK(gl)ISR_
RPS27A Ubiquitylation K152 4.747 4.970 _CCLTYCFNK(gl)PEDK_
RPS27A Ubiquitylation K156 4.809 _CCLTYCFNKPEDK(gl)_
SKP1 Ubiquitylation K130 0.138 0.140 _GK(gl)TPEEIRK_
SKP1 Phosphorylation T131 -0.024 -0.138 _GKT(ph)PEEIRK_
SKP1 Ubiquitylation K142 0.165 0.894 _TFNIK(gl)NDFTEEEEAQVRK_
SKP1 Ubiquitylation K155 -0.096 0.069 _K(gl)ENQWCEEK_
SKP1 Ubiquitylation K163 0.109 -0.020 _ENQWCEEK(gl)_
SKP2 Phosphorylation S8 -1.062 _SNLGHPES(ph)PPRK_
SKP2 Phosphorylation S64 -1.144 -1.189 _EEPDSENIPQELLSNLGHPES(ph)PPR_
SKP2 Phosphorylation S75 0.512 0.657 _SKGS(ph)DKDFVIVR_
SKP2 Ubiquitylation K228 -0.475 _LSDPIVNTLAK(gl)NSNLVR_
SKP2 Ubiquitylation K420 -1.178 _LTLQK(gl)PSCL_
TFDP1 Phosphorylation S23 -0.667 -0.353 _VFIDQNLS(ph)PGK_
TFDP1 Ubiquitylation K320 -0.549 0.052 _MGMACGLESGSCSAEDLK(gl)MAR_
UBA52 Ubiquitylation K6 1.066 0.995 _MQIFVK(gl)TLTGK_
UBA52 Ubiquitylation K11 -0.488 -0.081 _TLTGK(gl)TITLEVEPSDTIENVKAK(gl)_
UBA52 Ubiquitylation K27 -0.882 -0.159 _TLTGK(gl)TITLEVEPSDTIENVK(gl)AK_
UBA52 Ubiquitylation K29 -1.087 -1.029 _AK(gl)IQDK(gl)EGIPPDQQR_
UBA52 Ubiquitylation K33 -0.736 -0.407 _IQDK(gl)EGIPPDQQR_
UBA52 Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBA52 Phosphorylation S57 1.909 0.548 _TLS(ph)DYNIQK_
UBA52 Ubiquitylation K63 0.276 0.299 _TLSDYNIQK(gl)ESTLHLVLR_
UBA52 Ubiquitylation K93 0.181 2.418 _YNCDK(gl)MICR_
UBA52 Ubiquitylation K99 0.109 2.111 _VK(gl)LAVLK_
UBA52 Ubiquitylation K104 0.674 2.102 _LAVLK(gl)YYK_
UBA52 Ubiquitylation K107 2.949 3.611 _YYK(gl)VDENGK(gl)ISR_
UBA52 Ubiquitylation K113 1.572 3.672 _YYK(gl)VDENGK(gl)ISR_
UBA52 Ubiquitylation K152 4.747 4.970 _CCLTYCFNK(gl)PEDK_
UBA52 Ubiquitylation K156 4.809 _CCLTYCFNKPEDK(gl)_


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