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Query: CKS1B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CKS1B 0 0.123 -0.980 1.540

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CKS1B Ubiquitylation K30 -0.426 -0.991 _DIAK(gl)LVPK_

Background Information for CKS1B:


Pubmed-CKS1B »
Uniprot-CKS1B »
Biogrid-CKS1B »
ProteomicsDB-CKS1B »

Tumorportal-CKS1B »
COSMIC-CKS1B »
GenomeRNAi-CKS1B »
Genecards-CKS1B


Protein-protein Interactions for CKS1B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCNA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCNB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait GMNN Cat. description Hein, Mann, Cell 2015
Category members IP bait SKP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CKS1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IKZF5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIM49 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CKS1B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Cyclin-dep_kinase_reg-sub IPR000789 0.22


Protein complexes (CORUM database) featuring CKS1B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3015 p27-cyclinE-Cdk2 - Ubiquitin E3 ligase (SKP1A, SKP2, CUL1, CKS1B, RBX1) complex Database 0.28
Category members Corum 5319 CDH1-CKS1B complex Database 0.08
Category members Corum 3036 Ubiquitin E3 ligase (SKP1A, SKP2, CUL1, CKS1B, RBX1) Database 0.04


Categories featuring CKS1B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members Pathway Pathway_315 REACTOME_S_PHASE 0 2.19
Category members Pathway Pathway_322 REACTOME_G1_S_TRANSITION 0 1.77
Category members Pathway Pathway_313 REACTOME_MITOTIC_G1_G1_S_PHASES 0 1.45
Category members GO Category GO:0000082 G1/S transition of mitotic cell cycle Database 1.23
Category members GO Category GO:0051301 cell division Database 1.15
Category members Pathway Pathway_968 PID_FOXM1_PATHWAY 0 0.8
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members Pathway Pathway_782 REACTOME_SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21 0 0.66
Category members Pathway Pathway_835 REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ 0 0.63
Category members GO Category GO:0016301 kinase activity Database 0.23
Category members GO Category GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity Database 0.13
Category members Pathway Pathway_973 BIOCARTA_P27_PATHWAY 0 0.1
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members Pathway Pathway_791 REACTOME_G1_PHASE 0 0.02
Category members Pathway Pathway_24 KEGG_PATHWAYS_IN_CANCER 0 0
Category members Pathway Pathway_283 KEGG_SMALL_CELL_LUNG_CANCER 0 0
Category members GO Category GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity Database 0


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