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Results for the Category
regulation of cyclin-dependent protein serine/threonine kinase activity
(GO:0000079)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
GTF2H1 3 -0.470 0.340 0.260 2.656 2.859 1.092 0.966
ANAPC2 3 2.010 -0.680 0.379 0.170 0.854 -0.575 0.408
CCNT2 1 -1.850 3.910
CDK5RAP3 1 -1.460 2.740 0.905
CDK5RAP3 1 -1.460 2.740
CDK5RAP3 1 -1.460 2.740 0.784 1.125
CCND1 1 -1.820 3.470
CCND2 1 1.210 -0.610
MNAT1 0 -0.030 -0.100 0.666
CCNK 0 -0.940 0.500 -1.137 -1.242 0.561 -0.665 0.806
CCNK 0 -0.940 0.500
CDC6 0 -1.190 2.070
CDKN3 0 0.480 -0.130
CDK5RAP1 0 -0.230 0.000
CCNE1 0 0.460 -0.980
CDC37 0 -1.030 1.190 0.339 0.690 1.087
GTPBP4 0 -1.150 1.590 -0.623 -0.725
GTPBP4 0 -1.150 1.590 -0.486 0.142
BCCIP 0 0.530 -0.880 0.379 0.228 -0.115
CCNY 0 0.030 0.400
CCNY 0 0.030 0.400
CCNC 0 0.760 -0.860
CCNG1 0 0.760 -0.640
CNPPD1 0 -0.230 1.110
GADD45A 0 1.050 -0.170
CKS2 0 -0.160 0.130
CDKN1A 0 1.080 -0.750
PKMYT1 0 -0.470 0.850
CCNT1 0 0.720 -0.430 1.355 1.434
CCNB1 0 -0.410 -0.128 0.212 -0.166 -0.523
CCNH 0 1.480 -0.550
HERC5 0 -0.330 1.710
CCNA2 0 -0.530 0.260
CCNO 0 -0.720 0.660
CCNB2 0
CDC25C 0 -0.100 0.100
CCNYL1 0 1.160 -0.870
CCNL1 0 -0.190 -0.660 -0.513 0.214
CDC25A 0 0.260 -0.100
CKS1B 0 -0.980 1.540
SFN 0 0.890 0.120 -4.300
BLM 0 1.270 -0.830 -0.850 -0.141 0.144 0.151 0.149
BLM 0 1.270 -0.830
CCNL2 0 0.610 0.430

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ANAPC2 Phosphorylation S218 -0.012 0.026 _LLQS(ph)PLCAGCSSDK_
ANAPC2 Phosphorylation S314 -0.286 0.054 _VFLQDGPARPAS(ph)PEAGNTLR_
ANAPC2 Phosphorylation S534 0.186 1.648 _LLHQFSFS(ph)PER_
ANAPC2 Ubiquitylation K546 -0.496 -0.462 _NVELLK(gl)LR_
ANAPC2 Ubiquitylation K624 2.177 _AALEAYCK(gl)K_
ANAPC2 Ubiquitylation K625 2.177 _AALEAYCK(gl)K_
BCCIP Ubiquitylation K159 -0.071 0.374 _NCEK(gl)SMVEQLDK_
BCCIP Ubiquitylation K231 -0.327 -0.101 _TFVEAGK(gl)NNSK_
BCCIP Ubiquitylation K235 -0.327 -0.101 _TFVEAGK(gl)NNSK_
BLM Phosphorylation S144 1.234 _KLEFSSS(ph)PDSLSTINDWDDMDDFDTSETSK_
CCNA2 Ubiquitylation K54 -0.746 _AALAVLK(gl)SGNPR_
CCNA2 Ubiquitylation K68 -1.274 _GLAQQQRPK(gl)TR_
CCNB1 Ubiquitylation K18 -0.455 _AK(gl)INMAGAK_
CCNB1 Ubiquitylation K36 -1.833 -2.301 _VPTAPAATSK(gl)PGLRPR_
CCNB1 Ubiquitylation K59 -0.659 _VSEQLQAK(gl)MPMK_
CCNB1 Ubiquitylation K288 0.578 _QMEMK(gl)ILR_
CCNB2 Phosphorylation S92 -0.838 -0.676 _GPS(ph)PTPEDVSMKEENLCQAFSDALLCK_
CCNC Ubiquitylation K117 0.126 _LIAAATSVLK(gl)TR_
CCND1 Ubiquitylation K33 -0.490 _AMLK(gl)AEETCAPSVSYFK_
CCND1 Ubiquitylation K46 -1.016 -0.036 _AEETCAPSVSYFK(gl)CVQK_
CCND1 Ubiquitylation K95 -0.733 -0.137 _FLSLEPVK(gl)K_
CCND1 Ubiquitylation K96 -0.846 -0.155 _FLSLEPVKK(gl)_
CCND1 Ubiquitylation K238 0.245 _VIK(gl)CDPDCLR_
CCND2 Ubiquitylation K45 -0.759 -0.277 _YLPQCSYFK(gl)CVQK_
CCND2 Ubiquitylation K49 -0.524 _CVQK(gl)DIQPYMR_
CCND2 Ubiquitylation K113 -0.572 _LK(gl)ETSPLTAEK_
CCND2 Ubiquitylation K173 -1.137 0.202 _EK(gl)LSLIR_
CCND2 Phosphorylation S269 0.049 _DGS(ph)KSEDELDQASTPTDVR_
CCND2 Phosphorylation S271 2.155 _DGSKS(ph)EDELDQASTPTDVR_
CCNE1 Phosphorylation S100 -0.765 _IIAPS(ph)RGSPLPVLSWANR_
CCNE1 Phosphorylation S103 -0.765 _IIAPS(ph)RGSPLPVLSWANR_
CCNE1 Phosphorylation S387 0.705 -0.922 _AS(ph)PLPSGLLTPPQSGK_
CCNG1 Ubiquitylation K187 0.399 _LEAQLK(gl)ACHCR_
CCNH Ubiquitylation K189 0.418 _K(gl)TADDFLNR_
CCNK Ubiquitylation K118 0.624 _DIIK(gl)TAR_
CCNK Phosphorylation S340 0.324 0.494 _RAVVVS(ph)PKEENK_
CCNL1 Phosphorylation T325 -1.444 _GLNPDGT(ph)PALSTLGGFSPASKPS(ph)SPR_
CCNL1 Phosphorylation S329 -1.624 _GLNPDGTPALS(ph)TLGGFSPAS(ph)KPSSPR_
CCNL1 Phosphorylation S335 -1.494 -1.192 _GLNPDGTPALSTLGGFS(ph)PASKPS(ph)SPR_
CCNL1 Phosphorylation S341 -1.490 -0.994 _GLNPDGTPALSTLGGFS(ph)PASKPS(ph)SPR_
CCNL1 Phosphorylation S342 -1.498 _GLNPDGTPALSTLGGFS(ph)PASKPSS(ph)PR_
CCNL1 Phosphorylation S352 0.572 0.579 _AEEKS(ph)PISINVK_
CCNL2 Phosphorylation S330 -0.186 -0.377 _GLLPGGTQVLDGTSGFS(ph)PAPK_
CCNL2 Phosphorylation S338 0.602 0.674 _LVES(ph)PKEGK_
CCNL2 Phosphorylation S348 0.257 0.086 _GSKPS(ph)PLSVK_
CCNO Phosphorylation S81 -0.913 _GGS(ph)PLPGPAQPVAQLDLQTFR_
CCNT2 Phosphorylation S480 -0.420 _QGQSQAASSSSVTS(ph)PIK_
CCNT2 Phosphorylation S601 -0.068 0.175 _S(ph)PVGLSSDGISSSSSSSR_
CCNY Phosphorylation S25 0.133 0.065 _LES(ph)YRPDTDLSR_
CCNY Ubiquitylation K94 0.840 _ASTIFLSK(gl)SQTDVR_
CCNY Phosphorylation S324 0.375 _S(ph)ASADNLTLPR_
CCNY Phosphorylation S326 0.283 0.544 _SAS(ph)ADNLTLPR_
CCNYL1 Ubiquitylation K94 0.840 _ASTIFLSK(gl)SQTDVR_
CCNYL1 Phosphorylation S112 0.527 _SNHLNHVS(ph)PGQLTK_
CCNYL1 Phosphorylation S344 0.882 1.131 _SFS(ph)ADNFIGIQR_
CDC25A Ubiquitylation K120 1.111 _LLGCSPALK(gl)R_
CDC25C Phosphorylation S185 -0.645 _YLGS(ph)PITTVPK_
CDC25C Phosphorylation S233 -0.702 -0.657 _SPS(ph)MPENLNRPR_
CDC25C Phosphorylation S280 0.256 0.326 _TVS(ph)LCDITITQMLEEDSNQGHLIGDFSK_
CDC37 Phosphorylation S5 0.600 0.297 _(ac)VDYS(ph)VWDHIEVSDDEDETHPNIDTASLFR_
CDC37 Phosphorylation S13 0.017 0.075 _(ac)VDYSVWDHIEVS(ph)DDEDETHPNIDTASLFR_
CDC37 Ubiquitylation K45 -0.075 _MEQFQK(gl)EKEELDR_
CDC37 Ubiquitylation K69 0.281 _LK(gl)ELEVAEGGK_
CDC37 Ubiquitylation K132 -0.873 _SMVNTK(gl)PEKTEEDSEEVR_
CDC37 Ubiquitylation K157 0.330 _TFVEKYEK(gl)QIK_
CDC37 Ubiquitylation K330 -0.426 0.035 _MDPTDAK(gl)YHMQR_
CDC37 Ubiquitylation K352 -1.772 _ASEAK(gl)EGEEAGPGDPLLEAVPK_
CDC6 Ubiquitylation K33 1.448 _NSSDAK(gl)LEPTNVQTVTCSPR_
CDC6 Phosphorylation S45 -0.996 _LEPTNVQTVTCS(ph)PR_
CDC6 Phosphorylation S54 -0.860 _ALPLS(ph)PR_
CDC6 Phosphorylation S106 -0.049 _LVFDNQLTIKS(ph)PSK_
CDC6 Ubiquitylation K221 1.075 _ILQDLKK(gl)_
CDK5RAP1 Ubiquitylation K189 -0.716 _LK(gl)EEILNR_
CDK5RAP1 Ubiquitylation K348 -1.373 _GFTTNYKTK(gl)_
CDK5RAP1 Ubiquitylation K396 -1.590 _DNICK(gl)QIHLPAQSGSSR_
CDK5RAP1 Ubiquitylation K487 -1.858 _LK(gl)DDVPEEVK_
CDK5RAP1 Ubiquitylation K495 -1.951 _LKDDVPEEVK(gl)LR_
CDK5RAP3 Ubiquitylation K191 0.393 0.766 _EQFYHSCK(gl)QYGITGENVR_
CDK5RAP3 Ubiquitylation K467 0.155 _LK(gl)QSQLLALKK_
CDK5RAP3 Ubiquitylation K503 -0.651 _LDLLLEK(gl)TK_
CDK5RAP3 Ubiquitylation K517 0.755 0.828 _LIEADISK(gl)R_
CDKN1A Ubiquitylation K188 -2.505 -1.077 _QTSMTDFYHSK(gl)R_
CDKN3 Ubiquitylation K86 -0.893 0.100 _GELSK(gl)YR_
CKS1B Ubiquitylation K30 -0.426 -0.991 _DIAK(gl)LVPK_
CKS2 Ubiquitylation K4 -0.212 -0.347 _(ac)AHK(gl)QIYYSDK_
CKS2 Ubiquitylation K30 -0.639 -1.741 _ELSK(gl)QVPK_
CNPPD1 Ubiquitylation K80 -0.812 _K(gl)YVAHVSR_
CNPPD1 Ubiquitylation K404 -0.526 _LK(gl)SFVFPG_
GADD45A Ubiquitylation K12 -0.515 0.281 _TLEEFSAGEQK(gl)TER_
GADD45A Ubiquitylation K29 0.092 _VGDALEEVLSK(gl)ALSQR_
GTF2H1 Ubiquitylation K240 2.338 _LNTGSK(gl)DLFAECAK_
GTPBP4 Ubiquitylation K187 0.585 _SSFINK(gl)VTR_
HERC5 Ubiquitylation K397 -3.968 _TIPTLNEGTVK(gl)R_
HERC5 Ubiquitylation K406 -1.155 _WIADVETK(gl)R_
MNAT1 Phosphorylation S279 0.003 0.225 _AAS(ph)PQDLAGGYTSSLACHR_
PKMYT1 Ubiquitylation K58 -1.709 _SLPPPPPAK(gl)GSIPISR_
SFN Ubiquitylation K11 0.561 0.388 _AK(gl)LAEQAER_
SFN Ubiquitylation K49 -0.093 0.337 _NLLSVAYK(gl)_


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