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Query: CDKN3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CDKN3 0 -0.793 0.480 -0.130

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CDKN3 Ubiquitylation K86 -0.893 0.100 _GELSK(gl)YR_

Background Information for CDKN3:


Pubmed-CDKN3 »
Uniprot-CDKN3 »
Biogrid-CDKN3 »
ProteomicsDB-CDKN3 »

Tumorportal-CDKN3 »
COSMIC-CDKN3 »
GenomeRNAi-CDKN3 »
Genecards-CDKN3


Protein-protein Interactions for CDKN3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CDKN3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Tyr_Pase_rcpt/non-rcpt IPR000242 0
Category members Dual-sp_phosphatase_cat-dom IPR000340 0
Category members Tyr/Dual-sp_Pase IPR000387 0
Category members Tyr_Pase_cat IPR003595 0
Category members Prot-tyrosine_phosphatase-like IPR029021 0


Protein complexes (CORUM database) featuring CDKN3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CDKN3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0000082 G1/S transition of mitotic cell cycle Database 1.23
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity Database 0.13
Category members GO Category GO:0004722 protein serine/threonine phosphatase activity Database 0.11
Category members GO Category GO:0004721 phosphoprotein phosphatase activity Database 0.11
Category members Disease phenotype HEPATOCELLULAR_CARCINOMA HEPATOCELLULAR CARCINOMA Database 0.09
Category members GO Category GO:0004725 protein tyrosine phosphatase activity Database 0
Category members GO Category GO:0006470 protein dephosphorylation Database 0
Category members GO Category GO:0007050 cell cycle arrest Database 0
Category members GO Category GO:0008138 protein tyrosine/serine/threonine phosphatase activity Database 0
Category members GO Category GO:0016311 dephosphorylation Database 0
Category members GO Category GO:0016791 phosphatase activity Database 0
Category members GO Category GO:0035335 peptidyl-tyrosine dephosphorylation Database 0


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