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protein serine/threonine phosphatase activity
(GO:0004722)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
PPP1CA 3 2.150 -0.860
PPP1CA 3 2.150 -0.860 -0.250 0.634 0.981 -0.108 0.171
PPM1G 2 -0.190 -0.120 -0.705 0.316 0.971 1.049
PPP1CC 2 0.390 -0.090
PPP1CC 2 0.390 -0.090 0.568 0.526 0.917 -0.533 0.173
PPP1CB 2 -0.790 1.500
PPP1CB 2 -0.790 1.500 0.568 0.526 0.917 -0.533 0.173
PPP1CB 2 -0.790 1.500 0.439 0.908 1.224 -0.104 0.029
PPP2CB 1 2.210 -0.980 0.194 0.044 0.215
PPP2CB 1 2.210 -0.980 0.650 1.189
PPP2R1A 1 -0.260 -0.200 0.714 0.973
PPP2R1A 1 -0.260 -0.200 -0.003 -0.196 0.057
PPP2R1A 1 -0.260 -0.200 1.697 1.450 -1.553
PPP2R1B 1 1.240 -0.730 1.697 1.450 -1.553
PPP2R5D 1 -0.110 0.620
PPP2R5D 1 -0.110 0.620 -0.455 -0.019
PPA2 1 -0.030 -0.180 1.652 -0.677 -2.027 0.607 1.273
PPP5C 0 -0.140 -0.230 0.937
PPP5C 0 -0.140 -0.230
MTMR3 0 0.400 -0.600
MTMR3 0 0.510 -0.480
CDKN3 0 0.480 -0.130
PPM1A 0 -0.680 1.340 0.402
PPM1A 0 -0.680 1.340 -1.556 -0.874
TIMM50 0 0.710 -0.640 0.428 -0.608 -0.459 -1.171 -0.634
PPP3CB 0 -1.240 2.140 -0.298 1.130
PPP3CB 0 -1.240 2.140 0.923 0.537
PPP2CA 0 0.160 -0.540 0.194 0.044 0.215
PPP2CA 0 0.160 -0.540 0.650 1.189
PPP6C 0 0.340 -0.620 0.715 -0.944 -0.116 0.577
ILKAP 0 -0.310 -0.170 -0.420 0.461
PPM1B 0 -0.180 0.420 -0.429 0.307
PPM1B 0 -0.180 0.420 0.248
PPP3CA 0 1.550 -1.230 -0.298 1.130
PPP3CA 0 1.550 -1.230 0.923 0.537
MTMR6 0 -0.340 0.720
PPP4C 0 -0.050 0.050 0.322
PPEF2 0
PPP1R15B 0 0.820 -0.760
PPM1K 0 0.560 -0.840
PPM1D 0 -0.190 -0.110
CYCS 0 -0.020 -0.350 0.711 0.320
PPM1E 0 0.690 -0.090
LCK 0 -0.490 1.390 0.295 0.576

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CDKN3 Ubiquitylation K86 -0.893 0.100 _GELSK(gl)YR_
CYCS Ubiquitylation K40 -2.265 _K(gl)TGQAPGYSYTAANK(gl)NK_
CYCS Ubiquitylation K54 -0.872 -1.922 _K(gl)TGQAPGYSYTAANK(gl)NK_
CYCS Ubiquitylation K56 -0.872 -1.922 _TGQAPGYSYTAANKNK(gl)_
CYCS Ubiquitylation K101 -1.859 _ADLIAYLKK(gl)_
ILKAP Phosphorylation S13 -0.127 -0.533 _(ac)M(ox)DLFGDLPEPERS(ph)PRPAAGK_
LCK Phosphorylation T37 -0.435 _YRPENTPEPVSTSVSHYGAEPT(ph)TVSPCPSSSAK_
LCK Ubiquitylation K191 -0.112 0.264 _ESETTK(gl)GAYSLSIR_
LCK Ubiquitylation K235 0.323 _AQFDTLQK(gl)LVK_
LCK Ubiquitylation K259 -1.613 _LTTVCPTVK(gl)PQTQGLAK_
MTMR3 Ubiquitylation K259 0.489 _NADDEHLVQSVAK(gl)ACASDSR_
MTMR3 Phosphorylation T611 0.583 0.519 _T(ph)RSYDNLTTACDNTVPLASR_
MTMR3 Phosphorylation S613 0.041 0.122 _S(ph)YDNLTTACDNTVPLASR_
MTMR3 Phosphorylation S633 0.471 0.821 _RCS(ph)DPSLNEK_
MTMR3 Phosphorylation S647 -0.030 0.268 _S(ph)LELSSLAGPGEDPLSADSLGKPTR_
MTMR3 Phosphorylation T731 -0.553 0.016 _RKT(ph)PEASAIGLHQDPELGDAALR_
MTMR6 Phosphorylation S556 -0.057 0.086 _ELLHS(ph)VHPESPNLK_
MTMR6 Phosphorylation S561 -0.441 0.120 _ELLHSVHPES(ph)PNLK_
PPA2 Phosphorylation S317 0.152 0.108 _SLVESVSSS(ph)PNKESNEEEQVWHFLGK_
PPEF2 Phosphorylation Y466 1.425 _GGGCY(ph)FGPDVTQQLLQKYNMQFLIRS(ph)HECK_
PPEF2 Phosphorylation S487 1.425 _GGGCY(ph)FGPDVTQQLLQKYNMQFLIRS(ph)HECK_
PPM1A Ubiquitylation K278 -0.176 _VCNEVVDTCLYK(gl)GSR_
PPM1B Ubiquitylation K90 -0.117 _AAGK(gl)SGSALELSVENVK_
PPM1D Phosphorylation S85 -1.520 _DPLPDAGAS(ph)PAPSR_
PPM1E Ubiquitylation K329 -0.500 _FVQK(gl)AAR_
PPM1G Phosphorylation S183 2.866 2.103 _SGGGTGEEPGS(ph)QGLNGEAGPEDSTR_
PPM1G Ubiquitylation K209 -1.051 -0.856 _ETPSQENGPTAK(gl)AYTGFSSNSER_
PPM1G Ubiquitylation K247 -2.531 _GTEAGQVGEPGIPTGEAGPSCSSASDK(gl)LPR_
PPM1G Ubiquitylation K339 -0.202 0.936 _GK(gl)QLIVANAGDSR_
PPM1G Ubiquitylation K383 0.075 0.659 _NAGGK(gl)VTMDGR_
PPM1G Ubiquitylation K519 -0.336 -0.692 _NTAELQPESGK(gl)R_
PPM1K Ubiquitylation K281 -1.828 _TSGVIAEPETK(gl)R_
PPP1CA Ubiquitylation K6 0.594 0.414 _(ac)SDSEK(gl)LNLDSIIGR_
PPP1CA Ubiquitylation K50 -0.131 0.478 _GLCLK(gl)SR_
PPP1CA Ubiquitylation K150 0.321 0.619 _IYGFYDECK(gl)RR_
PPP1CA Ubiquitylation K156 0.883 1.047 _YNIK(gl)LWK_
PPP1CA Ubiquitylation K247 0.313 _FLHK(gl)HDLDLICR_
PPP1CA Ubiquitylation K269 2.628 2.591 _AHQVVEDGYEFFAK(gl)R_
PPP1CB Ubiquitylation K146 0.352 _FNIK(gl)LWK_
PPP1CB Ubiquitylation K150 0.321 0.619 _IYGFYDECK(gl)RR_
PPP1CB Ubiquitylation K269 2.628 2.591 _AHQVVEDGYEFFAK(gl)R_
PPP1CC Ubiquitylation K35 -0.280 -0.504 _GSKPGK(gl)NVQLQENEIR_
PPP1CC Ubiquitylation K50 -0.131 0.478 _GLCLK(gl)SR_
PPP1CC Ubiquitylation K150 0.321 0.619 _IYGFYDECK(gl)RR_
PPP1CC Ubiquitylation K156 0.883 1.047 _YNIK(gl)LWK_
PPP1CC Ubiquitylation K247 0.313 _FLHK(gl)HDLDLICR_
PPP1CC Ubiquitylation K269 2.628 2.591 _AHQVVEDGYEFFAK(gl)R_
PPP1CC Phosphorylation T320 -0.561 _KPNATRPVT(ph)PPR_
PPP1CC Ubiquitylation K328 0.848 0.425 _GMITK(gl)QAK_
PPP1R15B Ubiquitylation K705 -1.323 _LQGTCFK(gl)GLNVLK_
PPP2CA Ubiquitylation K4 -0.788 -0.378 _(ac)MDDK(gl)AFTK_
PPP2CA Ubiquitylation K4 -0.450 -0.016 _(ac)M(ox)DEK(gl)VFTK_
PPP2CA Ubiquitylation K8 -0.522 _VFTK(gl)ELDQWIEQLNECK_
PPP2CA Ubiquitylation K21 -1.370 _ELDQWVEQLNECK(gl)QLNENQVR_
PPP2CA Ubiquitylation K21 -1.106 _ELDQWIEQLNECK(gl)QLSESQVK_
PPP2CA Ubiquitylation K29 0.211 0.122 _QLSESQVK(gl)SLCEK_
PPP2CA Ubiquitylation K36 -0.455 0.187 _AK(gl)EILTK_
PPP2CA Ubiquitylation K36 -0.455 0.187 _AK(gl)EILTK_
PPP2CA Ubiquitylation K41 -0.049 0.003 _EILTK(gl)ESNVQEVR_
PPP2CA Ubiquitylation K74 -0.316 -0.316 _IGGK(gl)SPDTNYLFMGDYVDR_
PPP2CB Ubiquitylation K4 -0.788 -0.378 _(ac)MDDK(gl)AFTK_
PPP2CB Ubiquitylation K4 -0.450 -0.016 _(ac)M(ox)DEK(gl)VFTK_
PPP2CB Ubiquitylation K8 -0.522 _VFTK(gl)ELDQWIEQLNECK_
PPP2CB Ubiquitylation K21 -1.370 _ELDQWVEQLNECK(gl)QLNENQVR_
PPP2CB Ubiquitylation K21 -1.106 _ELDQWIEQLNECK(gl)QLSESQVK_
PPP2CB Ubiquitylation K29 0.211 0.122 _QLSESQVK(gl)SLCEK_
PPP2CB Ubiquitylation K36 -0.455 0.187 _AK(gl)EILTK_
PPP2CB Ubiquitylation K36 -0.455 0.187 _AK(gl)EILTK_
PPP2CB Ubiquitylation K41 -0.049 0.003 _EILTK(gl)ESNVQEVR_
PPP2CB Ubiquitylation K74 -0.316 -0.316 _IGGK(gl)SPDTNYLFMGDYVDR_
PPP2R1A Ubiquitylation K34 0.304 _K(gl)LSTIALALGVER_
PPP2R1A Ubiquitylation K107 0.584 0.441 _DK(gl)AVESLR_
PPP2R1A Ubiquitylation K163 0.106 0.149 _VSSAVK(gl)AELR_
PPP2R1A Ubiquitylation K175 -0.351 _ASNAVK(gl)AEIR_
PPP2R1A Ubiquitylation K188 0.395 0.130 _AAASK(gl)LGEFAK_
PPP2R1A Ubiquitylation K255 0.301 0.202 _QAAEDK(gl)SWR_
PPP2R1A Ubiquitylation K266 0.464 0.338 _YMVADK(gl)FTELQK_
PPP2R1A Ubiquitylation K284 -0.575 _FSELQK(gl)AMGPK_
PPP2R1A Ubiquitylation K307 0.224 0.500 _VK(gl)EFCENLSADCR_
PPP2R1A Ubiquitylation K467 0.890 _EAATSNLK(gl)K_
PPP2R1A Ubiquitylation K468 0.890 _EAATSNLK(gl)K_
PPP2R1A Ubiquitylation K542 -0.187 _FNVAK(gl)SLQK_
PPP2R1B Ubiquitylation K175 -0.351 _ASNAVK(gl)AEIR_
PPP2R1B Ubiquitylation K284 -0.575 _FSELQK(gl)AMGPK_
PPP2R5D Phosphorylation T63 -1.449 _RPSNST(ph)PPPTQLSK_
PPP2R5D Ubiquitylation K232 -0.302 _FLESPDFQPNIAK(gl)K_
PPP2R5D Ubiquitylation K233 -0.302 0.665 _FLESPDFQPNIAKK(gl)_
PPP2R5D Ubiquitylation K409 -0.010 _QLAK(gl)CVSSPHFQVAER_
PPP2R5D Phosphorylation S573 0.524 0.357 _RKS(ph)ELPQDVYTIK_
PPP2R5D Phosphorylation S598 -0.317 1.858 _RAEEFLTAS(ph)QEAL_
PPP3CA Ubiquitylation K32 -0.137 _LTAK(gl)EVFDNDGKPR_
PPP3CA Ubiquitylation K56 0.132 _VDVLK(gl)NHLVK_
PPP3CA Ubiquitylation K323 0.705 _AAVLK(gl)YENNVMNIR_
PPP3CA Ubiquitylation K405 0.078 _AIGK(gl)MAR_
PPP3CB Ubiquitylation K32 -0.137 _LTAK(gl)EVFDNDGKPR_
PPP3CB Ubiquitylation K56 0.132 _VDVLK(gl)NHLVK_
PPP3CB Ubiquitylation K323 0.705 _AAVLK(gl)YENNVMNIR_
PPP3CB Ubiquitylation K405 0.078 _AIGK(gl)MAR_
PPP4C Ubiquitylation K26 -0.494 -0.192 _ESEVK(gl)ALCAK(gl)AR_
PPP4C Ubiquitylation K31 -0.607 0.349 _ESEVK(gl)ALCAK(gl)AR_
PPP4C Ubiquitylation K133 -0.603 _K(gl)YGSVTVWR_
PPP5C Ubiquitylation K42 -0.703 _AK(gl)DYENAIK_
PPP6C Ubiquitylation K25 -0.474 _YLPENDLK(gl)R_
TIMM50 Ubiquitylation K167 -0.380 _AQGPQQQPGSEGPSYAK(gl)K_
TIMM50 Ubiquitylation K168 -0.380 _AQGPQQQPGSEGPSYAK(gl)K_
TIMM50 Ubiquitylation K353 -0.109 _VVVVDCK(gl)K_
TIMM50 Ubiquitylation K354 -0.109 _VVVVDCK(gl)K_
TIMM50 Ubiquitylation K434 0.302 _LAELSK(gl)SNK_
TIMM50 Ubiquitylation K437 0.101 -0.071 _SNK(gl)QNLFLGSLTSR_


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