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Query: PPM1E

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PPM1E 0 -0.500 0.690 -0.090

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PPM1E Ubiquitylation K329 -0.500 _FVQK(gl)AAR_

Background Information for PPM1E:


Pubmed-PPM1E »
Uniprot-PPM1E »
Biogrid-PPM1E »
ProteomicsDB-PPM1E »

Tumorportal-PPM1E »
COSMIC-PPM1E »
GenomeRNAi-PPM1E »
Genecards-PPM1E


Protein-protein Interactions for PPM1E
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C20orf7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ICMT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPM1E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRMT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PPM1E
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PP2C-like_dom IPR001932 0.04


Protein complexes (CORUM database) featuring PPM1E
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PPM1E
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0004722 protein serine/threonine phosphatase activity Database 0.11
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0035690 cellular response to drug Database 0.1
Category members GO Category GO:0006469 negative regulation of protein kinase activity Database 0
Category members GO Category GO:0006470 protein dephosphorylation Database 0
Category members GO Category GO:0035970 peptidyl-threonine dephosphorylation Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0051496 positive regulation of stress fiber assembly Database 0


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