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cellular response to drug
(GO:0035690)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
CAD 1 1.760 -0.990 -0.363 -0.027 0.051
NME2 0 0.040 0.180 -0.783 0.303 -0.394 -0.805 -0.898
MEF2A 0 0.820 -0.530
MEF2A 0 0.820 -0.530
MEF2C 0 -0.980 1.550
MEF2C 0 -0.980 1.550
REST 0 -0.120 -0.050 -0.002 -1.235 -0.636
RBM22 0 0.250 0.540 -0.425 -1.788 0.001 -1.588 -0.510
PPP3CB 0 -1.240 2.140 -0.298 1.130
PPP3CB 0 -1.240 2.140 0.923 0.537
UMPS 0 1.150 -0.870 0.030 -0.319 -0.237
PPAT 0 -0.100 -0.040
TXN 0 1.900 -1.090 1.120 0.196 -5.026
MYC 0 0.170 0.550 -2.443 -0.949 -0.454 -1.290
PPP3CA 0 1.550 -1.230 -0.298 1.130
PPP3CA 0 1.550 -1.230 0.923 0.537
TP53 0 -1.070 1.050 -2.808 0.076 -0.094 0.436 0.497
EIF2B5 0 -0.630 0.250 -0.711 0.154 -0.822
EGFR 0 -0.580 0.520 0.513 0.090
PPM1E 0 0.690 -0.090
GAS6 0 0.020 0.220 -1.517 -0.502
NME1 0 0.510 -0.420 0.232 0.470
NME1 0 0.510 -0.420 -0.783 0.303 -0.394 -0.805 -0.898

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CAD Ubiquitylation K739 -0.732 -0.798 _NSVTGGTAAFEPSVDYCVVK(gl)IPR_
CAD Ubiquitylation K760 0.489 _IGSCMK(gl)SVGEVMGIGR_
CAD Ubiquitylation K778 -0.005 _SFEEAFQK(gl)ALR_
CAD Ubiquitylation K1119 -1.239 _FLSSAAAVSK(gl)EHPVVISK_
CAD Ubiquitylation K1211 -0.235 -0.502 _DDQLK(gl)VIECNVR_
CAD Ubiquitylation K1309 0.012 -0.277 _AMLSTGFK(gl)IPK_
CAD Ubiquitylation K1325 -0.719 -0.613 _NK(gl)SELLPTVR_
CAD Phosphorylation S1406 0.530 0.612 _RLS(ph)SFVTK_
CAD Ubiquitylation K1411 -0.215 -0.224 _RLSSFVTK(gl)GYR_
CAD Ubiquitylation K1460 0.321 _VHVDCMTSQK(gl)LVR_
CAD Ubiquitylation K1657 2.804 -1.545 _LGPGK(gl)GEVRPELGSR_
CAD Phosphorylation T1827 -1.407 _WPQGAVPQLPPSAPAT(ph)SEMTTTPERPR_
CAD Phosphorylation S1859 -0.178 -0.084 _IHRAS(ph)DPGLPAEEPKEK_
EGFR Phosphorylation T693 0.486 -0.139 _ELVEPLT(ph)PSGEAPNQALLR_
EGFR Phosphorylation S991 -0.041 _MHLPS(ph)PTDSNFYR_
EIF2B5 Phosphorylation S544 0.200 0.349 _GGS(ph)PQM(ox)DDIK_
MEF2A Ubiquitylation K23 -0.140 _QVTFTK(gl)R_
MEF2A Phosphorylation S235 0.664 -0.092 _AS(ph)PNLIGATGANSLGK_
MEF2A Phosphorylation T253 -1.271 _VMPT(ph)KSPPPPGGGNLGMNSR_
MEF2A Phosphorylation S255 -1.235 _VMPTKS(ph)PPPPGGGNLGMNSR_
MEF2A Phosphorylation S408 -0.173 -0.049 _SEPIS(ph)PPRDR_
MEF2A Phosphorylation S494 -0.858 -1.232 _GDFHSPIVLGRPPNTEDRES(ph)PSVK_
MEF2C Ubiquitylation K23 -0.140 _QVTFTK(gl)R_
MEF2C Phosphorylation S240 0.008 0.302 _NS(ph)PGLLVSPGNLNK_
MEF2C Phosphorylation S406 0.272 0.338 _SEPVS(ph)PPRDR_
MYC Phosphorylation S20 -1.444 -1.145 _PLNVS(ph)FTNR_
MYC Phosphorylation T72 -1.699 -1.813 _FELLPT(ph)PPLS(ph)PSRR_
MYC Phosphorylation S76 -1.777 -1.435 _FELLPTPPLS(ph)PSR_
MYC Phosphorylation S81 0.459 _S(ph)GLCSPSYVAVTPFSLR_
MYC Phosphorylation S85 0.199 0.073 _SGLCS(ph)PSYVAVTPFSLR_
MYC Ubiquitylation K162 -2.475 -1.259 _LVSEK(gl)LASYQAAR_
MYC Phosphorylation S295 -0.903 _SESGS(ph)PSAGGHSKPPHSPLVLK_
MYC Phosphorylation S307 -1.486 _SES(ph)GSPSAGGHSKPPHS(ph)PLVLK_
MYC Ubiquitylation K340 -2.449 _VK(gl)LDSVR_
MYC Ubiquitylation K403 -3.432 _DQIPELENNEK(gl)APK_
NME1 Ubiquitylation K37 0.192 0.188 _TFIAIK(gl)PDGVQR_
NME1 Ubiquitylation K51 -0.368 0.345 _GLVGEIIK(gl)R_
NME1 Ubiquitylation K56 -0.240 _FEQK(gl)GFR_
NME1 Ubiquitylation K125 -0.693 -0.414 _VMLGETNPADSK(gl)PGTIR_
NME1 Ubiquitylation K264 0.448 0.582 _NIIHGSDSVK(gl)SAEK_
NME2 Ubiquitylation K37 0.192 0.188 _TFIAIK(gl)PDGVQR_
NME2 Ubiquitylation K51 -0.368 0.345 _GLVGEIIK(gl)R_
NME2 Ubiquitylation K56 -0.240 _FEQK(gl)GFR_
NME2 Ubiquitylation K125 -0.693 -0.414 _VMLGETNPADSK(gl)PGTIR_
NME2 Ubiquitylation K264 0.448 0.582 _NIIHGSDSVK(gl)SAEK_
PPAT Ubiquitylation K403 -1.376 _GNTISPIIK(gl)LLK_
PPAT Ubiquitylation K406 -1.376 _GNTISPIIK(gl)LLK_
PPM1E Ubiquitylation K329 -0.500 _FVQK(gl)AAR_
PPP3CA Ubiquitylation K32 -0.137 _LTAK(gl)EVFDNDGKPR_
PPP3CA Ubiquitylation K56 0.132 _VDVLK(gl)NHLVK_
PPP3CA Ubiquitylation K323 0.705 _AAVLK(gl)YENNVMNIR_
PPP3CA Ubiquitylation K405 0.078 _AIGK(gl)MAR_
PPP3CB Ubiquitylation K32 -0.137 _LTAK(gl)EVFDNDGKPR_
PPP3CB Ubiquitylation K56 0.132 _VDVLK(gl)NHLVK_
PPP3CB Ubiquitylation K323 0.705 _AAVLK(gl)YENNVMNIR_
PPP3CB Ubiquitylation K405 0.078 _AIGK(gl)MAR_
REST Ubiquitylation K280 0.406 _VYTCGK(gl)CNYFSDR_
REST Phosphorylation S864 -3.456 _ESVSTEDLSPPS(ph)PPLPK_
TP53 Ubiquitylation K120 -0.188 _LGFLHSGTAK(gl)SVTCTYSPALNK_
TP53 Ubiquitylation K164 0.157 -1.260 _AMAIYK(gl)QSQHMTEVVR_
TP53 Phosphorylation S314 -0.695 -1.000 _ALPNNTSS(ph)SPQPK_
TP53 Phosphorylation S315 -0.762 -0.959 _RALPNNTSSS(ph)PQPK_
TP53 Ubiquitylation K320 -0.978 _ALPNNTSSSPQPKK(gl)_
TP53 Ubiquitylation K357 -0.231 -0.823 _ELNEALELKDAQAGK(gl)EPGGSR_
TXN Ubiquitylation K94 0.520 _VGEFSGANK(gl)EK_


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