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Query: PPAT

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PPAT 0 -1.416 -0.100 -0.040

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PPAT Ubiquitylation K403 -1.376 _GNTISPIIK(gl)LLK_
PPAT Ubiquitylation K406 -1.376 _GNTISPIIK(gl)LLK_

Background Information for PPAT:





Protein-protein Interactions for PPAT

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait B2M Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPAT Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PPAT

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PRTase-like IPR029057 0.32
Category members GATase_dom IPR000583 0.08
Category members PRibTrfase_dom IPR000836 0.08
Category members Ntn_hydrolases_N IPR029055 0


Protein complexes (CORUM database) featuring PPAT

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PPAT

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0000082 G1/S transition of mitotic cell cycle Database 1.23
Category members GO Category GO:0042493 response to drug Database 0.66
Category members GO Category GO:0032869 cellular response to insulin stimulus Database 0.63
Category members GO Category GO:0051289 protein homotetramerization Database 0.44
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0019693 ribose phosphate metabolic process Database 0.33
Category members Pathway Pathway_273 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS 0 0.23
Category members Pathway Pathway_68 KEGG_PURINE_METABOLISM 0 0.23
Category members Pathway Pathway_204 REACTOME_PURINE_METABOLISM 0 0.22
Category members GO Category GO:0006189 'de novo' IMP biosynthetic process Database 0.13
Category members GO Category GO:0009168 purine ribonucleoside monophosphate biosynthetic process Database 0.12
Category members GO Category GO:0006144 purine nucleobase metabolic process Database 0.11
Category members GO Category GO:0035690 cellular response to drug Database 0.1
Category members Pathway Pathway_272 KEGG_ALANINE_ASPARTATE_AND_GLUTAMATE_METABOLISM 0 0.04
Category members GO Category GO:0031100 organ regeneration Database 0.01
Category members GO Category GO:0006543 glutamine catabolic process Database 0
Category members Pathway Pathway_206 REACTOME_METABOLISM_OF_NUCLEOTIDES 0 0
Category members GO Category GO:0001822 kidney development Database 0
Category members GO Category GO:0006164 purine nucleotide biosynthetic process Database 0
Category members GO Category GO:0007595 lactation Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0009113 purine nucleobase biosynthetic process Database 0
Category members GO Category GO:0009116 nucleoside metabolic process Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0051539 4 iron, 4 sulfur cluster binding Database 0
Category members GO Category GO:0055086 nucleobase-containing small molecule metabolic process Database 0
Category members GO Category GO:0060135 maternal process involved in female pregnancy Database 0


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