Results for the Category
purine nucleobase biosynthetic process
(GO:0009113)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| PAICS | 1 | -1.870 | 3.350 | -0.267 | -0.199 | 0.430 | 0.202 | -0.105 |
| SHMT1 | 1 | -0.120 | 0.930 | |||||
| SHMT1 | 1 | -0.120 | 0.930 | 0.878 | 1.600 | -2.560 | 0.964 | 0.784 |
| PPAT | 0 | -0.100 | -0.040 | |||||
| GMPS | 0 | -0.740 | 0.600 | -0.533 | -0.030 | 0.022 | -0.466 | -0.160 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| GMPS | Ubiquitylation | K120 | 0.343 | _VFGGTVHK(gl)K_ | |
| GMPS | Ubiquitylation | K121 | 0.457 | _VFGGTVHKK(gl)_ | |
| GMPS | Ubiquitylation | K165 | 1.104 | _VADGFK(gl)VVAR_ | |
| GMPS | Ubiquitylation | K182 | 0.575 | 0.078 | _SGNIVAGIANESK(gl)K_ |
| GMPS | Ubiquitylation | K183 | 0.652 | 0.078 | _SGNIVAGIANESKK(gl)_ |
| GMPS | Ubiquitylation | K288 | 0.285 | _ESQSVEEALK(gl)K_ | |
| GMPS | Ubiquitylation | K289 | -0.344 | 0.223 | _K(gl)LGIQVK_ |
| GMPS | Phosphorylation | T330 | -0.017 | _TLNM(ox)T(ph)TSPEEK_ | |
| GMPS | Phosphorylation | T331 | 0.917 | _TLNMTT(ph)SPEEK_ | |
| GMPS | Phosphorylation | S332 | 0.573 | 0.448 | _TLNMTTS(ph)PEEK_ |
| GMPS | Ubiquitylation | K457 | -0.834 | _VICAEEPYICK(gl)DFPETNNILK_ | |
| PAICS | Ubiquitylation | K11 | 0.118 | 0.212 | _(ac)ATAEVLNIGK(gl)K_ |
| PAICS | Phosphorylation | S27 | -0.894 | -0.106 | _TKEVYELLDS(ph)PGK_ |
| PAICS | Ubiquitylation | K36 | -0.192 | _VLLQSK(gl)DQITAGNAAR_ | |
| PAICS | Ubiquitylation | K110 | -0.265 | 0.236 | _RIATGSFLK(gl)R_ |
| PAICS | Ubiquitylation | K116 | 0.835 | -0.502 | _NPGVK(gl)EGYK_ |
| PAICS | Ubiquitylation | K235 | -0.533 | -1.432 | _DLK(gl)EVTPEGLQMVK_ |
| PAICS | Phosphorylation | T238 | 0.946 | 0.573 | _DLKEVT(ph)PEGLQMVK_ |
| PAICS | Ubiquitylation | K246 | -0.043 | _EVTPEGLQMVK(gl)K_ | |
| PAICS | Ubiquitylation | K247 | -0.584 | _EVTPEGLQMVKK(gl)_ | |
| PAICS | Ubiquitylation | K261 | 0.245 | -0.141 | _VELLLK(gl)SESQCR_ |
| PAICS | Ubiquitylation | K286 | -0.134 | 0.168 | _K(gl)ACGNFGIPCELR_ |
| PAICS | Ubiquitylation | K304 | -0.204 | -0.728 | _VTSAHK(gl)GPDETLR_ |
| PPAT | Ubiquitylation | K403 | -1.376 | _GNTISPIIK(gl)LLK_ | |
| PPAT | Ubiquitylation | K406 | -1.376 | _GNTISPIIK(gl)LLK_ | |
| SHMT1 | Ubiquitylation | K72 | -0.735 | _AVLEALGSCLNNK(gl)YSEGYPGQR_ | |
| SHMT1 | Ubiquitylation | K103 | -2.726 | -0.554 | _YSEGYPGK(gl)R_ |
| SHMT1 | Ubiquitylation | K280 | -0.564 | _HADIVTTTTHK(gl)TLR_ | |
| SHMT1 | Ubiquitylation | K356 | 1.096 | _EYSLQVLK(gl)NAR_ | |
| SHMT1 | Ubiquitylation | K386 | -0.881 | _VLEACSIACNK(gl)NTCPGDR_ | |
| SHMT1 | Ubiquitylation | K409 | 0.692 | _VLELVSITANK(gl)NTCPGDR_ | |
| SHMT1 | Ubiquitylation | K416 | -0.549 | -0.533 | _GLLEK(gl)DFQK_ |
| SHMT1 | Ubiquitylation | K446 | -1.125 | _ATLK(gl)EFK_ | |
| SHMT1 | Ubiquitylation | K469 | -0.436 | _LQDFK(gl)SFLLK_ | |
| SHMT1 | Ubiquitylation | K474 | -1.113 | -0.594 | _SFLLK(gl)DSETSQR_ |
.
© Copyright Svejstrup Laboratory 2015