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Query: PAICS

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PAICS 1 6.001 -1.870 3.350 -0.267 -0.199 0.430 0.202 -0.105

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PAICS Phosphorylation T238 0.946 0.573 _DLKEVT(ph)PEGLQMVK_
PAICS Ubiquitylation K110 -0.265 0.236 _RIATGSFLK(gl)R_
PAICS Ubiquitylation K11 0.118 0.212 _(ac)ATAEVLNIGK(gl)K_
PAICS Ubiquitylation K286 -0.134 0.168 _K(gl)ACGNFGIPCELR_
PAICS Ubiquitylation K246 -0.043 _EVTPEGLQMVK(gl)K_
PAICS Phosphorylation S27 -0.894 -0.106 _TKEVYELLDS(ph)PGK_
PAICS Ubiquitylation K261 0.245 -0.141 _VELLLK(gl)SESQCR_
PAICS Ubiquitylation K36 -0.192 _VLLQSK(gl)DQITAGNAAR_
PAICS Ubiquitylation K116 0.835 -0.502 _NPGVK(gl)EGYK_
PAICS Ubiquitylation K247 -0.584 _EVTPEGLQMVKK(gl)_
PAICS Ubiquitylation K304 -0.204 -0.728 _VTSAHK(gl)GPDETLR_
PAICS Ubiquitylation K235 -0.533 -1.432 _DLK(gl)EVTPEGLQMVK_

Background Information for PAICS:





Protein-protein Interactions for PAICS

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HNRNPA1L2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MTA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait POLR2G Cat. description Hein, Mann, Cell 2015
Category members IP bait PRPF3 Cat. description Hein, Mann, Cell 2015


Protein Domains in PAICS

Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring PAICS

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PAICS

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members Pathway Pathway_273 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS 0 0.23
Category members Pathway Pathway_68 KEGG_PURINE_METABOLISM 0 0.23
Category members Pathway Pathway_204 REACTOME_PURINE_METABOLISM 0 0.22
Category members GO Category GO:0006189 'de novo' IMP biosynthetic process Database 0.13
Category members GO Category GO:0009168 purine ribonucleoside monophosphate biosynthetic process Database 0.12
Category members GO Category GO:0006144 purine nucleobase metabolic process Database 0.11
Category members Pathway Pathway_206 REACTOME_METABOLISM_OF_NUCLEOTIDES 0 0
Category members GO Category GO:0009113 purine nucleobase biosynthetic process Database 0
Category members GO Category GO:0055086 nucleobase-containing small molecule metabolic process Database 0


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