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REACTOME_METABOLISM_OF_NUCLEOTIDES
(Pathway_206)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
IMPDH1 2 -0.140 -0.120 0.626 0.542
CAT 2 2.260 -1.180 1.895 -0.238
AK2 1 0.380 -0.820 1.981 0.248 -0.715
RRM2B 1 -0.160 -0.120
CAD 1 1.760 -0.990 -0.363 -0.027 0.051
AMPD2 1 2.140 -1.310
PAICS 1 -1.870 3.350 -0.267 -0.199 0.430 0.202 -0.105
DCK 1 0.440 -0.560
CMPK1 1 -2.700 5.830
RRM1 1 0.717 1.039 0.509
RRM2 1
PFAS 1 2.630 -0.920 0.784 0.586 0.847
APRT 1 -0.660 1.020 -4.051
NME2 0 0.040 0.180 -0.783 0.303 -0.394 -0.805 -0.898
TYMP 0 0.510 -0.670 -4.772
ADSS 0 -0.040 -0.580 -0.323
CTPS2 0 -1.090 1.190 0.011 0.338 0.641
NT5C2 0 1.960 -1.080
DHODH 0 -0.520 0.170 -1.249 -0.292
NME4 0 -0.090 0.400 0.563 0.436
GSR 0 -0.310 0.020 -0.452 -1.012 0.319 0.351
AK1 0 -1.080 1.190
UMPS 0 1.150 -0.870 0.030 -0.319 -0.237
DGUOK 0 1.670 -0.860 -0.140
DGUOK 0 1.670 -0.860
NT5C 0 -0.270 0.710
PPAT 0 -0.100 -0.040
DUT 0 -0.440 1.310
DUT 0 -0.440 1.310
DUT 0 -0.440 1.310
UCK1 0 0.630 -0.530
TXN 0 1.900 -1.090 1.120 0.196 -5.026
ATIC 0 -0.830 0.480 -0.329 0.553
UCK2 0 0.130 -0.610 -0.525
GUK1 0 1.050 -0.730
ADK 0 0.210 0.300
GART 0 0.954
GART 0 0.224 0.496
GMPS 0 -0.740 0.600 -0.533 -0.030 0.022 -0.466 -0.160
HPRT1 0 -0.840 0.070 -0.388 0.526
HPRT1 0 -0.840 0.070 1.039
TK1 0 0.610 -0.460
TYMS 0 -1.190 1.570
IMPDH2 0 -1.000 1.830 0.860 0.260 0.421 1.006 0.467
ADA 0 0.340 -0.830
TXNRD1 0 -0.400 -0.200
PNP 0 -0.590 0.270 -3.285
NME1 0 0.510 -0.420 0.232 0.470
NME1 0 0.510 -0.420 -0.783 0.303 -0.394 -0.805 -0.898
ADSL 0 0.990 -0.600
ADSL 0 0.990 -0.600 -0.508 0.257 -0.090

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ADA Ubiquitylation K312 0.123 _STLDTDYQMTK(gl)R_
ADK Ubiquitylation K117 -0.137 _FGEILK(gl)R_
ADK Ubiquitylation K256 0.320 0.493 _EQGFETK(gl)DIKEIAK_
ADSL Phosphorylation S9 0.246 0.261 _(ac)AAGGDHGS(ph)PDSYR_
ADSL Ubiquitylation K243 -0.448 _MVTEK(gl)AGFKR_
ADSL Ubiquitylation K309 -1.057 _QQIGSSAMPYK(gl)R_
ADSL Ubiquitylation K429 -0.148 _VLSQQAASVVK(gl)QEGGDNDLIER_
ADSS Ubiquitylation K118 -0.813 _GK(gl)GLEGWEK_
ADSS Ubiquitylation K125 0.267 _GLEGWEK(gl)R_
ADSS Ubiquitylation K157 -0.039 _QEQAGK(gl)NLGTTK_
ADSS Ubiquitylation K173 -0.819 -0.534 _GIGPVYSSK(gl)AAR_
ADSS Ubiquitylation K419 -0.511 _AFK(gl)ELPVNAQNYVR_
ADSS Ubiquitylation K447 0.344 0.415 _WIGVGK(gl)SR_
AK1 Ubiquitylation K99 0.474 _DAMVAK(gl)VNTSK_
AK2 Ubiquitylation K28 -2.435 -1.363 _AVLLGPPGAGK(gl)GTQAPR_
AK2 Ubiquitylation K63 -0.244 _AMVASGSELGKK(gl)_
AK2 Ubiquitylation K65 -0.229 _LK(gl)ATMDAGK_
AMPD2 Phosphorylation S76 0.719 _RAS(ph)LQASTAAPEAR_
AMPD2 Phosphorylation S100 0.448 -0.155 _S(ph)LPGPAPCLK_
AMPD2 Phosphorylation S168 0.601 0.268 _QIS(ph)QDVKLEPDILLR_
APRT Phosphorylation S30 -0.936 _DIS(ph)PVLKDPASFR_
APRT Ubiquitylation K34 -1.117 -1.579 _DISPVLK(gl)DPASFR_
APRT Ubiquitylation K114 -0.036 0.252 _AELEIQK(gl)DALEPGQR_
ATIC Ubiquitylation K195 -0.448 _K(gl)QYSKGVSQMPLR_
ATIC Ubiquitylation K199 -0.427 -0.247 _QYSK(gl)GVSQMPLR_
ATIC Ubiquitylation K397 0.429 _NNGVVDK(gl)SLFSNVVTK_
ATIC Ubiquitylation K406 0.213 0.405 _SLFSNVVTK(gl)NK_
ATIC Ubiquitylation K408 0.438 0.468 _SLFSNVVTKNK(gl)_
CAD Ubiquitylation K739 -0.732 -0.798 _NSVTGGTAAFEPSVDYCVVK(gl)IPR_
CAD Ubiquitylation K760 0.489 _IGSCMK(gl)SVGEVMGIGR_
CAD Ubiquitylation K778 -0.005 _SFEEAFQK(gl)ALR_
CAD Ubiquitylation K1119 -1.239 _FLSSAAAVSK(gl)EHPVVISK_
CAD Ubiquitylation K1211 -0.235 -0.502 _DDQLK(gl)VIECNVR_
CAD Ubiquitylation K1309 0.012 -0.277 _AMLSTGFK(gl)IPK_
CAD Ubiquitylation K1325 -0.719 -0.613 _NK(gl)SELLPTVR_
CAD Phosphorylation S1406 0.530 0.612 _RLS(ph)SFVTK_
CAD Ubiquitylation K1411 -0.215 -0.224 _RLSSFVTK(gl)GYR_
CAD Ubiquitylation K1460 0.321 _VHVDCMTSQK(gl)LVR_
CAD Ubiquitylation K1657 2.804 -1.545 _LGPGK(gl)GEVRPELGSR_
CAD Phosphorylation T1827 -1.407 _WPQGAVPQLPPSAPAT(ph)SEMTTTPERPR_
CAD Phosphorylation S1859 -0.178 -0.084 _IHRAS(ph)DPGLPAEEPKEK_
CMPK1 Ubiquitylation K75 -0.120 _K(gl)NPDSQYGELIEK_
CMPK1 Ubiquitylation K138 -0.030 0.576 _NQDNLQGWNK(gl)TMDGK_
DCK Phosphorylation S15 3.826 _RSCPSFSAS(ph)SEGTR_
DCK Phosphorylation S74 2.649 _WCNVQSTQDEFEELTMS(ph)QK_
DGUOK Ubiquitylation K135 -1.130 _K(gl)PVQIFER_
DGUOK Ubiquitylation K275 -1.478 _EVNTFVK(gl)NL_
DHODH Ubiquitylation K235 -0.190 _LLTK(gl)VLQER_
DUT Phosphorylation S4 0.191 0.429 _PCS(ph)EETPAIS(ph)PSK_
DUT Phosphorylation S11 -0.548 -0.435 _PCSEETPAIS(ph)PSK_
DUT Phosphorylation S13 -0.394 _PCSEETPAISPS(ph)KR_
DUT Ubiquitylation K14 -0.852 -1.290 _PCSEETPAISPSK(gl)R_
DUT Phosphorylation S16 -0.212 _(ac)AAGGAAPETPAISPS(ph)K_
DUT Phosphorylation S88 -0.883 -0.900 _AGGS(ph)PAPGPETPAISPSK_
DUT Phosphorylation S99 -3.045 _AGGSPAPGPETPAIS(ph)PSK_
DUT Phosphorylation S101 -1.411 _AGGSPAPGPETPAISPS(ph)K_
GART Ubiquitylation K143 -0.597 -1.216 _SAGVQCFGPTAEAAQLESSK(gl)R_
GART Ubiquitylation K192 0.536 -0.182 _ASGLAAGK(gl)GVIVAK_
GART Ubiquitylation K198 0.297 _GVIVAK(gl)SKEEACK_
GART Ubiquitylation K200 -0.291 _GVIVAKSK(gl)_
GART Ubiquitylation K205 0.253 _SKEEACK(gl)AVQEIMQEK_
GART Ubiquitylation K255 -2.473 _TVAPMPPAQDHK(gl)R_
GART Ubiquitylation K287 0.489 0.084 _IK(gl)DTVLQR_
GART Ubiquitylation K321 -0.008 -0.399 _NGPK(gl)VLEFNCR_
GART Ubiquitylation K440 -0.081 _ENLISALEEAK(gl)K_
GART Ubiquitylation K488 -0.011 0.475 _ESGVDIAAGNMLVK(gl)K_
GART Ubiquitylation K489 0.108 0.475 _ESGVDIAAGNMLVKK(gl)_
GART Ubiquitylation K495 -0.620 -0.249 _IQPLAK(gl)ATSR_
GART Ubiquitylation K521 -0.504 -0.094 _AAGFK(gl)DPLLASGTDGVGTK_
GART Phosphorylation S838 1.377 0.399 _NGSLTNHFS(ph)FEKK_
GART Ubiquitylation K888 -0.230 _AAVAGLDK(gl)AER_
GART Ubiquitylation K902 0.189 -0.741 _VINHK(gl)LYK_
GMPS Ubiquitylation K120 0.343 _VFGGTVHK(gl)K_
GMPS Ubiquitylation K121 0.457 _VFGGTVHKK(gl)_
GMPS Ubiquitylation K165 1.104 _VADGFK(gl)VVAR_
GMPS Ubiquitylation K182 0.575 0.078 _SGNIVAGIANESK(gl)K_
GMPS Ubiquitylation K183 0.652 0.078 _SGNIVAGIANESKK(gl)_
GMPS Ubiquitylation K288 0.285 _ESQSVEEALK(gl)K_
GMPS Ubiquitylation K289 -0.344 0.223 _K(gl)LGIQVK_
GMPS Phosphorylation T330 -0.017 _TLNM(ox)T(ph)TSPEEK_
GMPS Phosphorylation T331 0.917 _TLNMTT(ph)SPEEK_
GMPS Phosphorylation S332 0.573 0.448 _TLNMTTS(ph)PEEK_
GMPS Ubiquitylation K457 -0.834 _VICAEEPYICK(gl)DFPETNNILK_
GSR Ubiquitylation K296 0.979 _FSQVK(gl)EVKK_
GSR Ubiquitylation K340 0.183 -0.002 _VPNTK(gl)DLSLNK_
GUK1 Ubiquitylation K213 -0.004 -0.180 _NTETEESLVK(gl)R_
HPRT1 Phosphorylation S5 -0.474 _S(ph)PGVVISDDEPGYDLDLFCIPNHYAEDLER_
HPRT1 Ubiquitylation K103 0.354 -0.199 _LK(gl)SYCNDQSTGDIK_
HPRT1 Ubiquitylation K159 0.923 0.525 _MVK(gl)VASLLVK_
HPRT1 Ubiquitylation K166 -0.029 -0.428 _VASLLVK(gl)R_
HPRT1 Ubiquitylation K175 -1.570 _SVGYK(gl)PDFVGFEIPDK_
HPRT1 Ubiquitylation K215 0.354 -0.516 _DLNHVCVISETGKAK(gl)_
IMPDH1 Phosphorylation T6 -0.746 -1.087 _(ac)M(ox)EGPLT(ph)PPPLQGGGAAAVPEPGAR_
IMPDH1 Ubiquitylation K293 0.154 0.299 _GK(gl)LPIVNDCDELVAIIAR_
IMPDH1 Ubiquitylation K327 2.285 1.616 _DSQK(gl)QLLCGAAVGTR_
IMPDH1 Ubiquitylation K507 0.433 _GMGSLDAMEK(gl)SSSSQKR_
IMPDH1 Ubiquitylation K523 0.629 _YFSEGDKVK(gl)_
IMPDH1 Ubiquitylation K535 0.179 -0.096 _IAQGVSGSIQDK(gl)GSIQK_
IMPDH2 Ubiquitylation K124 0.058 _YEQGFITDPVVLSPK(gl)DR_
IMPDH2 Ubiquitylation K134 0.709 0.285 _VRDVFEAK(gl)AR_
IMPDH2 Phosphorylation S160 0.758 0.744 _LVGIISS(ph)R_
IMPDH2 Ubiquitylation K208 -0.482 -0.007 _GK(gl)LPIVNEDDELVAIIAR_
IMPDH2 Ubiquitylation K293 0.119 _DK(gl)YPNLQVIGGNVVTAAQAK_
IMPDH2 Phosphorylation S416 0.362 0.652 _GMGS(ph)LDAMDK_
IMPDH2 Ubiquitylation K422 1.114 0.582 _GMGSLDAMDK(gl)HLSSQNR_
IMPDH2 Ubiquitylation K450 0.313 0.467 _VAQGVSGAVQDK(gl)GSIHK_
NME1 Ubiquitylation K37 0.192 0.188 _TFIAIK(gl)PDGVQR_
NME1 Ubiquitylation K51 -0.368 0.345 _GLVGEIIK(gl)R_
NME1 Ubiquitylation K56 -0.240 _FEQK(gl)GFR_
NME1 Ubiquitylation K125 -0.693 -0.414 _VMLGETNPADSK(gl)PGTIR_
NME1 Ubiquitylation K264 0.448 0.582 _NIIHGSDSVK(gl)SAEK_
NME2 Ubiquitylation K37 0.192 0.188 _TFIAIK(gl)PDGVQR_
NME2 Ubiquitylation K51 -0.368 0.345 _GLVGEIIK(gl)R_
NME2 Ubiquitylation K56 -0.240 _FEQK(gl)GFR_
NME2 Ubiquitylation K125 -0.693 -0.414 _VMLGETNPADSK(gl)PGTIR_
NME2 Ubiquitylation K264 0.448 0.582 _NIIHGSDSVK(gl)SAEK_
NT5C Phosphorylation S182 0.253 _LLS(ph)WSDNWR_
NT5C Ubiquitylation K194 -0.850 _EILDSK(gl)R_
NT5C2 Ubiquitylation K520 -0.887 _TSVDFKDTDYK(gl)R_
PAICS Ubiquitylation K11 0.118 0.212 _(ac)ATAEVLNIGK(gl)K_
PAICS Phosphorylation S27 -0.894 -0.106 _TKEVYELLDS(ph)PGK_
PAICS Ubiquitylation K36 -0.192 _VLLQSK(gl)DQITAGNAAR_
PAICS Ubiquitylation K110 -0.265 0.236 _RIATGSFLK(gl)R_
PAICS Ubiquitylation K116 0.835 -0.502 _NPGVK(gl)EGYK_
PAICS Ubiquitylation K235 -0.533 -1.432 _DLK(gl)EVTPEGLQMVK_
PAICS Phosphorylation T238 0.946 0.573 _DLKEVT(ph)PEGLQMVK_
PAICS Ubiquitylation K246 -0.043 _EVTPEGLQMVK(gl)K_
PAICS Ubiquitylation K247 -0.584 _EVTPEGLQMVKK(gl)_
PAICS Ubiquitylation K261 0.245 -0.141 _VELLLK(gl)SESQCR_
PAICS Ubiquitylation K286 -0.134 0.168 _K(gl)ACGNFGIPCELR_
PAICS Ubiquitylation K304 -0.204 -0.728 _VTSAHK(gl)GPDETLR_
PFAS Ubiquitylation K279 0.218 _FCDNSSAIQGK(gl)EVR_
PFAS Ubiquitylation K494 -0.832 _GDPEMEQK(gl)MNR_
PFAS Phosphorylation S569 0.616 0.660 _S(ph)PNRDFLTHVSAR_
PNP Ubiquitylation K183 0.081 -0.409 _ALSTWK(gl)QMGEQR_
PNP Ubiquitylation K269 0.183 _ANHEEVLAAGK(gl)QAAQK_
PPAT Ubiquitylation K403 -1.376 _GNTISPIIK(gl)LLK_
PPAT Ubiquitylation K406 -1.376 _GNTISPIIK(gl)LLK_
RRM1 Ubiquitylation K158 0.366 0.759 _SYLLK(gl)INGK_
RRM1 Ubiquitylation K376 0.409 0.370 _LYASYEK(gl)QGR_
RRM1 Ubiquitylation K414 0.015 _K(gl)SNQQNLGTIK_
RRM1 Ubiquitylation K465 -0.049 0.272 _K(gl)LAEVTK_
RRM1 Ubiquitylation K471 1.117 1.347 _LAEVTK(gl)VVVR_
RRM1 Ubiquitylation K496 0.699 1.559 _IIDINYYPVPEACLSNK(gl)R_
RRM1 Ubiquitylation K587 0.487 _VLKEK(gl)IAK_
RRM1 Ubiquitylation K590 -0.395 0.551 _IAK(gl)YGIR_
RRM1 Ubiquitylation K689 0.606 _TVWEISQK(gl)TVLK_
RRM1 Ubiquitylation K693 0.427 _TVLK(gl)MAAER_
RRM1 Ubiquitylation K733 0.748 _QGLK(gl)TGMYYLR_
RRM1 Ubiquitylation K754 -0.746 -1.217 _TRPAANPIQFTLNK(gl)EK_
RRM1 Ubiquitylation K756 -0.746 -1.217 _TRPAANPIQFTLNK(gl)EK_
RRM2 Phosphorylation S80 -1.483 -1.780 _VPLAPITDPQQLQLS(ph)PLK_
RRM2 Phosphorylation T93 -1.284 -0.534 _GLSLVDKENT(ph)PPALSGTR_
RRM2 Ubiquitylation K106 -0.247 _VLASK(gl)TAR_
RRM2 Ubiquitylation K121 -2.427 -0.884 _TK(gl)AAAPGVEDEPLLR_
RRM2 Ubiquitylation K424 2.394 -0.588 _TNFFEK(gl)R_
RRM2B Ubiquitylation K424 2.394 -0.588 _TNFFEK(gl)R_
TK1 Phosphorylation S13 -1.350 -1.354 _(ac)SCINLPTVLPGS(ph)PSK_
TK1 Phosphorylation S15 -1.567 -1.084 _SCINLPTVLPGSPS(ph)K_
TK1 Ubiquitylation K16 -1.664 _(ac)SCINLPTVLPGSPSK(gl)TR_
TXN Ubiquitylation K94 0.520 _VGEFSGANK(gl)EK_
TXNRD1 Ubiquitylation K580 -0.043 -0.178 _IICNTK(gl)DNER_
TYMS Ubiquitylation K99 -0.992 _GSTNAK(gl)ELSSK_
TYMS Ubiquitylation K104 -0.543 _ELSSK(gl)GVK_
TYMS Ubiquitylation K169 -0.801 -0.836 _VIDTIK(gl)TNPDDRR_
UCK1 Phosphorylation T256 1.212 0.752 _RT(ph)FSEPGDHPGM(ox)LTSGK_
UCK1 Phosphorylation S258 0.987 0.574 _TFS(ph)EPGDHPGMLTSGK_
UCK2 Ubiquitylation K75 0.162 _VLTSEQKAK(gl)_
UCK2 Ubiquitylation K99 -0.004 -0.101 _TLK(gl)EITEGK_
UCK2 Ubiquitylation K202 -1.119 _K(gl)YADVIIPR_


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