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Query: CMPK1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CMPK1 1 6.377 -2.700 5.830

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CMPK1 Ubiquitylation K138 -0.030 0.576 _NQDNLQGWNK(gl)TMDGK_
CMPK1 Ubiquitylation K75 -0.120 _K(gl)NPDSQYGELIEK_

Background Information for CMPK1:





Protein-protein Interactions for CMPK1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CMPK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CMPK1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Zeta_toxin_domain IPR010488 0.33
Category members Adenylat/UMP-CMP_kin IPR000850 0


Protein complexes (CORUM database) featuring CMPK1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CMPK1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0016301 kinase activity Database 0.23
Category members GO Category GO:0019205 nucleobase-containing compound kinase activity Database 0.2
Category members Pathway Pathway_277 KEGG_PYRIMIDINE_METABOLISM 0 0.18
Category members GO Category GO:0009220 pyrimidine ribonucleotide biosynthetic process Database 0.09
Category members GO Category GO:0006139 nucleobase-containing compound metabolic process Database 0.08
Category members GO Category GO:0018963 phthalate metabolic process Database 0.06
Category members Pathway Pathway_206 REACTOME_METABOLISM_OF_NUCLEOTIDES 0 0
Category members Pathway Pathway_274 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES 0 0
Category members GO Category GO:0004127 cytidylate kinase activity Database 0
Category members GO Category GO:0004550 nucleoside diphosphate kinase activity Database 0
Category members GO Category GO:0004849 uridine kinase activity Database 0
Category members GO Category GO:0006165 nucleoside diphosphate phosphorylation Database 0
Category members GO Category GO:0006222 UMP biosynthetic process Database 0
Category members GO Category GO:0006227 dUDP biosynthetic process Database 0
Category members GO Category GO:0009142 nucleoside triphosphate biosynthetic process Database 0
Category members GO Category GO:0015949 nucleobase-containing small molecule interconversion Database 0
Category members GO Category GO:0016776 phosphotransferase activity, phosphate group as acceptor Database 0
Category members GO Category GO:0019201 nucleotide kinase activity Database 0
Category members GO Category GO:0022602 ovulation cycle process Database 0
Category members GO Category GO:0033862 UMP kinase activity Database 0
Category members GO Category GO:0046939 nucleotide phosphorylation Database 0
Category members GO Category GO:0055086 nucleobase-containing small molecule metabolic process Database 0


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