Results for the Category
REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES
(Pathway_274)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| AK2 | 1 | 0.380 | -0.820 | 1.981 | 0.248 | -0.715 | ||
| RRM2B | 1 | -0.160 | -0.120 | |||||
| CMPK1 | 1 | -2.700 | 5.830 | |||||
| RRM1 | 1 | 0.717 | 1.039 | 0.509 | ||||
| RRM2 | 1 | |||||||
| NME2 | 0 | 0.040 | 0.180 | -0.783 | 0.303 | -0.394 | -0.805 | -0.898 |
| CTPS2 | 0 | -1.090 | 1.190 | 0.011 | 0.338 | 0.641 | ||
| NME4 | 0 | -0.090 | 0.400 | 0.563 | 0.436 | |||
| GSR | 0 | -0.310 | 0.020 | -0.452 | -1.012 | 0.319 | 0.351 | |
| AK1 | 0 | -1.080 | 1.190 | |||||
| TXN | 0 | 1.900 | -1.090 | 1.120 | 0.196 | -5.026 | ||
| GUK1 | 0 | 1.050 | -0.730 | |||||
| TXNRD1 | 0 | -0.400 | -0.200 | |||||
| NME1 | 0 | 0.510 | -0.420 | 0.232 | 0.470 | |||
| NME1 | 0 | 0.510 | -0.420 | -0.783 | 0.303 | -0.394 | -0.805 | -0.898 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| AK1 | Ubiquitylation | K99 | 0.474 | _DAMVAK(gl)VNTSK_ | |
| AK2 | Ubiquitylation | K28 | -2.435 | -1.363 | _AVLLGPPGAGK(gl)GTQAPR_ |
| AK2 | Ubiquitylation | K63 | -0.244 | _AMVASGSELGKK(gl)_ | |
| AK2 | Ubiquitylation | K65 | -0.229 | _LK(gl)ATMDAGK_ | |
| CMPK1 | Ubiquitylation | K75 | -0.120 | _K(gl)NPDSQYGELIEK_ | |
| CMPK1 | Ubiquitylation | K138 | -0.030 | 0.576 | _NQDNLQGWNK(gl)TMDGK_ |
| GSR | Ubiquitylation | K296 | 0.979 | _FSQVK(gl)EVKK_ | |
| GSR | Ubiquitylation | K340 | 0.183 | -0.002 | _VPNTK(gl)DLSLNK_ |
| GUK1 | Ubiquitylation | K213 | -0.004 | -0.180 | _NTETEESLVK(gl)R_ |
| NME1 | Ubiquitylation | K37 | 0.192 | 0.188 | _TFIAIK(gl)PDGVQR_ |
| NME1 | Ubiquitylation | K51 | -0.368 | 0.345 | _GLVGEIIK(gl)R_ |
| NME1 | Ubiquitylation | K56 | -0.240 | _FEQK(gl)GFR_ | |
| NME1 | Ubiquitylation | K125 | -0.693 | -0.414 | _VMLGETNPADSK(gl)PGTIR_ |
| NME1 | Ubiquitylation | K264 | 0.448 | 0.582 | _NIIHGSDSVK(gl)SAEK_ |
| NME2 | Ubiquitylation | K37 | 0.192 | 0.188 | _TFIAIK(gl)PDGVQR_ |
| NME2 | Ubiquitylation | K51 | -0.368 | 0.345 | _GLVGEIIK(gl)R_ |
| NME2 | Ubiquitylation | K56 | -0.240 | _FEQK(gl)GFR_ | |
| NME2 | Ubiquitylation | K125 | -0.693 | -0.414 | _VMLGETNPADSK(gl)PGTIR_ |
| NME2 | Ubiquitylation | K264 | 0.448 | 0.582 | _NIIHGSDSVK(gl)SAEK_ |
| RRM1 | Ubiquitylation | K158 | 0.366 | 0.759 | _SYLLK(gl)INGK_ |
| RRM1 | Ubiquitylation | K376 | 0.409 | 0.370 | _LYASYEK(gl)QGR_ |
| RRM1 | Ubiquitylation | K414 | 0.015 | _K(gl)SNQQNLGTIK_ | |
| RRM1 | Ubiquitylation | K465 | -0.049 | 0.272 | _K(gl)LAEVTK_ |
| RRM1 | Ubiquitylation | K471 | 1.117 | 1.347 | _LAEVTK(gl)VVVR_ |
| RRM1 | Ubiquitylation | K496 | 0.699 | 1.559 | _IIDINYYPVPEACLSNK(gl)R_ |
| RRM1 | Ubiquitylation | K587 | 0.487 | _VLKEK(gl)IAK_ | |
| RRM1 | Ubiquitylation | K590 | -0.395 | 0.551 | _IAK(gl)YGIR_ |
| RRM1 | Ubiquitylation | K689 | 0.606 | _TVWEISQK(gl)TVLK_ | |
| RRM1 | Ubiquitylation | K693 | 0.427 | _TVLK(gl)MAAER_ | |
| RRM1 | Ubiquitylation | K733 | 0.748 | _QGLK(gl)TGMYYLR_ | |
| RRM1 | Ubiquitylation | K754 | -0.746 | -1.217 | _TRPAANPIQFTLNK(gl)EK_ |
| RRM1 | Ubiquitylation | K756 | -0.746 | -1.217 | _TRPAANPIQFTLNK(gl)EK_ |
| RRM2 | Phosphorylation | S80 | -1.483 | -1.780 | _VPLAPITDPQQLQLS(ph)PLK_ |
| RRM2 | Phosphorylation | T93 | -1.284 | -0.534 | _GLSLVDKENT(ph)PPALSGTR_ |
| RRM2 | Ubiquitylation | K106 | -0.247 | _VLASK(gl)TAR_ | |
| RRM2 | Ubiquitylation | K121 | -2.427 | -0.884 | _TK(gl)AAAPGVEDEPLLR_ |
| RRM2 | Ubiquitylation | K424 | 2.394 | -0.588 | _TNFFEK(gl)R_ |
| RRM2B | Ubiquitylation | K424 | 2.394 | -0.588 | _TNFFEK(gl)R_ |
| TXN | Ubiquitylation | K94 | 0.520 | _VGEFSGANK(gl)EK_ | |
| TXNRD1 | Ubiquitylation | K580 | -0.043 | -0.178 | _IICNTK(gl)DNER_ |
.
© Copyright Svejstrup Laboratory 2015