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Query: CTPS2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CTPS2 0 2.180 -1.090 1.190 0.011 0.338 0.641

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for CTPS2:





Protein-protein Interactions for CTPS2

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait NASP Cat. description Hein, Mann, Cell 2015
Category members IP bait SNX3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CTPS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SUGP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TIGD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CTPS2

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members CTP_synthase IPR004468 0.08
Category members CTP_synthase_N IPR017456 0.08
Category members GATASE IPR017926 0.04
Category members Peptidase_C26 IPR011697 0.04
Category members Class_I_gatase-like IPR029062 0


Protein complexes (CORUM database) featuring CTPS2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CTPS2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0006541 glutamine metabolic process Database 0.47
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0016787 hydrolase activity Database 0.22
Category members Pathway Pathway_277 KEGG_PYRIMIDINE_METABOLISM 0 0.18
Category members GO Category GO:0003883 CTP synthase activity Database 0.08
Category members GO Category GO:0044210 'de novo' CTP biosynthetic process Database 0.08
Category members Pathway Pathway_206 REACTOME_METABOLISM_OF_NUCLEOTIDES 0 0
Category members Pathway Pathway_274 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES 0 0
Category members GO Category GO:0006220 pyrimidine nucleotide metabolic process Database 0
Category members GO Category GO:0006221 pyrimidine nucleotide biosynthetic process Database 0
Category members GO Category GO:0015949 nucleobase-containing small molecule interconversion Database 0
Category members GO Category GO:0055086 nucleobase-containing small molecule metabolic process Database 0


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