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Query: GUK1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GUK1 0 -0.185 1.050 -0.730

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GUK1 Ubiquitylation K213 -0.004 -0.180 _NTETEESLVK(gl)R_

Background Information for GUK1:


Pubmed-GUK1 »
Uniprot-GUK1 »
Biogrid-GUK1 »
ProteomicsDB-GUK1 »

Tumorportal-GUK1 »
COSMIC-GUK1 »
GenomeRNAi-GUK1 »
Genecards-GUK1


Protein-protein Interactions for GUK1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DPY19L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GUK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM97 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GUK1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members GK/Ca_channel_bsu IPR008145 1.36
Category members Guanylate_kin-like IPR008144 1.32


Protein complexes (CORUM database) featuring GUK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GUK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0004385 guanylate kinase activity Database 1.77
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_68 KEGG_PURINE_METABOLISM 0 0.23
Category members Pathway Pathway_38 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM 0 0.08
Category members GO Category GO:0046037 GMP metabolic process Database 0.05
Category members GO Category GO:0034436 glycoprotein transport Database 0.04
Category members Pathway Pathway_206 REACTOME_METABOLISM_OF_NUCLEOTIDES 0 0
Category members Pathway Pathway_274 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES 0 0
Category members GO Category GO:0006163 purine nucleotide metabolic process Database 0
Category members GO Category GO:0015949 nucleobase-containing small molecule interconversion Database 0
Category members GO Category GO:0017144 drug metabolic process Database 0
Category members GO Category GO:0019673 GDP-mannose metabolic process Database 0
Category members GO Category GO:0046034 ATP metabolic process Database 0
Category members GO Category GO:0046060 dATP metabolic process Database 0
Category members GO Category GO:0046939 nucleotide phosphorylation Database 0
Category members GO Category GO:0055086 nucleobase-containing small molecule metabolic process Database 0


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