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Query: AK1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AK1 0 1.664 -1.080 1.190

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AK1 Ubiquitylation K99 0.474 _DAMVAK(gl)VNTSK_

Background Information for AK1:


Pubmed-AK1 »
Uniprot-AK1 »
Biogrid-AK1 »
ProteomicsDB-AK1 »

Tumorportal-AK1 »
COSMIC-AK1 »
GenomeRNAi-AK1 »
Genecards-AK1


Protein-protein Interactions for AK1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AK1 Cat. description Hein, Mann, Cell 2015


Protein Domains in AK1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Zeta_toxin_domain IPR010488 0.33
Category members Adenylat/UMP-CMP_kin IPR000850 0
Category members AK1/5 IPR006267 0


Protein complexes (CORUM database) featuring AK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring AK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_68 KEGG_PURINE_METABOLISM 0 0.23
Category members GO Category GO:0016301 kinase activity Database 0.23
Category members GO Category GO:0019205 nucleobase-containing compound kinase activity Database 0.2
Category members GO Category GO:0006139 nucleobase-containing compound metabolic process Database 0.08
Category members Pathway Pathway_206 REACTOME_METABOLISM_OF_NUCLEOTIDES 0 0
Category members Pathway Pathway_274 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES 0 0
Category members GO Category GO:0001520 outer dense fiber Database 0
Category members GO Category GO:0004017 adenylate kinase activity Database 0
Category members GO Category GO:0004550 nucleoside diphosphate kinase activity Database 0
Category members GO Category GO:0006165 nucleoside diphosphate phosphorylation Database 0
Category members GO Category GO:0007050 cell cycle arrest Database 0
Category members GO Category GO:0009142 nucleoside triphosphate biosynthetic process Database 0
Category members GO Category GO:0015949 nucleobase-containing small molecule interconversion Database 0
Category members GO Category GO:0036126 sperm flagellum Database 0
Category members GO Category GO:0046034 ATP metabolic process Database 0
Category members GO Category GO:0055086 nucleobase-containing small molecule metabolic process Database 0


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