bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: NT5C2

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NT5C2 0 -0.887 1.960 -1.080

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NT5C2 Ubiquitylation K520 -0.887 _TSVDFKDTDYK(gl)R_

Background Information for NT5C2:


Pubmed-NT5C2 »
Uniprot-NT5C2 »
Biogrid-NT5C2 »
ProteomicsDB-NT5C2 »

Tumorportal-NT5C2 »
COSMIC-NT5C2 »
GenomeRNAi-NT5C2 »
Genecards-NT5C2


Protein-protein Interactions for NT5C2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HSPBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNX15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NT5C2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members HAD-SF_hydro_IG_5-nucl IPR008380 0
Category members Pur_nucleotidase IPR016695 0
Category members HAD-like_dom IPR023214 0


Protein complexes (CORUM database) featuring NT5C2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NT5C2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_68 KEGG_PURINE_METABOLISM 0 0.23
Category members Pathway Pathway_204 REACTOME_PURINE_METABOLISM 0 0.22
Category members Pathway Pathway_277 KEGG_PYRIMIDINE_METABOLISM 0 0.18
Category members GO Category GO:0008253 5'-nucleotidase activity Database 0.17
Category members GO Category GO:0006144 purine nucleobase metabolic process Database 0.11
Category members Pathway Pathway_38 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM 0 0.08
Category members Pathway Pathway_206 REACTOME_METABOLISM_OF_NUCLEOTIDES 0 0
Category members Pathway Pathway_281 KEGG_NICOTINATE_AND_NICOTINAMIDE_METABOLISM 0 0
Category members Pathway Pathway_284 REACTOME_PURINE_CATABOLISM 0 0
Category members GO Category GO:0006195 purine nucleotide catabolic process Database 0
Category members GO Category GO:0017144 drug metabolic process Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0055086 nucleobase-containing small molecule metabolic process Database 0


.

© Copyright Svejstrup Laboratory 2015