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Query: PNP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PNP 0 -2.832 -0.590 0.270 -3.285

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PNP Ubiquitylation K183 0.081 -0.409 _ALSTWK(gl)QMGEQR_
PNP Ubiquitylation K269 0.183 _ANHEEVLAAGK(gl)QAAQK_

Background Information for PNP:


Pubmed-PNP »
Uniprot-PNP »
Biogrid-PNP »
ProteomicsDB-PNP »

Tumorportal-PNP »
COSMIC-PNP »
GenomeRNAi-PNP »
Genecards-PNP


Protein-protein Interactions for PNP
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BATF3 Cat. description Hein, Mann, Cell 2015
Category members IP bait DDB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED10 Cat. description Hein, Mann, Cell 2015


Protein Domains in PNP
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Nucleoside_phosphorylase_d IPR000845 0


Protein complexes (CORUM database) featuring PNP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PNP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006955 immune response Database 1.22
Category members GO Category GO:0042493 response to drug Database 0.66
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0034418 urate biosynthetic process Database 0.29
Category members Pathway Pathway_68 KEGG_PURINE_METABOLISM 0 0.23
Category members Pathway Pathway_204 REACTOME_PURINE_METABOLISM 0 0.22
Category members Pathway Pathway_277 KEGG_PYRIMIDINE_METABOLISM 0 0.18
Category members GO Category GO:0006144 purine nucleobase metabolic process Database 0.11
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0006139 nucleobase-containing compound metabolic process Database 0.08
Category members GO Category GO:0042301 phosphate ion binding Database 0.07
Category members GO Category GO:0042102 positive regulation of T cell proliferation Database 0.04
Category members Pathway Pathway_205 REACTOME_PURINE_SALVAGE 0 0
Category members Pathway Pathway_206 REACTOME_METABOLISM_OF_NUCLEOTIDES 0 0
Category members Pathway Pathway_281 KEGG_NICOTINATE_AND_NICOTINAMIDE_METABOLISM 0 0
Category members Pathway Pathway_284 REACTOME_PURINE_CATABOLISM 0 0
Category members GO Category GO:0001882 nucleoside binding Database 0
Category members GO Category GO:0002060 purine nucleobase binding Database 0
Category members GO Category GO:0006195 purine nucleotide catabolic process Database 0
Category members GO Category GO:0008144 drug binding Database 0
Category members GO Category GO:0009116 nucleoside metabolic process Database 0
Category members GO Category GO:0043101 purine-containing compound salvage Database 0
Category members GO Category GO:0046638 positive regulation of alpha-beta T cell differentiation Database 0
Category members GO Category GO:0055086 nucleobase-containing small molecule metabolic process Database 0
Category members GO Category GO:0070970 interleukin-2 secretion Database 0


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