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Query: UCK2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
UCK2 0 -0.367 0.130 -0.610 -0.525

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
UCK2 Ubiquitylation K75 0.162 _VLTSEQKAK(gl)_
UCK2 Ubiquitylation K99 -0.004 -0.101 _TLK(gl)EITEGK_
UCK2 Ubiquitylation K202 -1.119 _K(gl)YADVIIPR_

Background Information for UCK2:





Protein-protein Interactions for UCK2

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait UCK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UPRT Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in UCK2

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members PRK IPR006082 0.18
Category members Uridine_kinase_like IPR000764 0
Category members Depp_CoAkinase IPR001977 0
Category members PRK/URK IPR006083 0


Protein complexes (CORUM database) featuring UCK2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring UCK2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0016301 kinase activity Database 0.23
Category members Pathway Pathway_277 KEGG_PYRIMIDINE_METABOLISM 0 0.18
Category members GO Category GO:0007631 feeding behavior Database 0.07
Category members GO Category GO:0048678 response to axon injury Database 0.01
Category members Pathway Pathway_206 REACTOME_METABOLISM_OF_NUCLEOTIDES 0 0
Category members Pathway Pathway_278 REACTOME_PYRIMIDINE_METABOLISM 0 0
Category members Pathway Pathway_77 KEGG_DRUG_METABOLISM_OTHER_ENZYMES 0 0
Category members GO Category GO:0004140 dephospho-CoA kinase activity Database 0
Category members GO Category GO:0004849 uridine kinase activity Database 0
Category members GO Category GO:0005575 cellular_component Database 0
Category members GO Category GO:0006206 pyrimidine nucleobase metabolic process Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0015937 coenzyme A biosynthetic process Database 0
Category members GO Category GO:0016773 phosphotransferase activity, alcohol group as acceptor Database 0
Category members GO Category GO:0019206 nucleoside kinase activity Database 0
Category members GO Category GO:0043097 pyrimidine nucleoside salvage Database 0
Category members GO Category GO:0044206 UMP salvage Database 0
Category members GO Category GO:0044211 CTP salvage Database 0
Category members GO Category GO:0055086 nucleobase-containing small molecule metabolic process Database 0


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