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KEGG_DRUG_METABOLISM_OTHER_ENZYMES
(Pathway_77)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
IMPDH1 2 -0.140 -0.120 0.626 0.542
UCKL1 1 -2.060 3.500
TYMP 0 0.510 -0.670 -4.772
UMPS 0 1.150 -0.870 0.030 -0.319 -0.237
ITPA 0 0.970 -0.680 -0.090
UCK1 0 0.630 -0.530
UCK2 0 0.130 -0.610 -0.525
GMPS 0 -0.740 0.600 -0.533 -0.030 0.022 -0.466 -0.160
HPRT1 0 -0.840 0.070 -0.388 0.526
HPRT1 0 -0.840 0.070 1.039
TK1 0 0.610 -0.460
IMPDH2 0 -1.000 1.830 0.860 0.260 0.421 1.006 0.467

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
GMPS Ubiquitylation K120 0.343 _VFGGTVHK(gl)K_
GMPS Ubiquitylation K121 0.457 _VFGGTVHKK(gl)_
GMPS Ubiquitylation K165 1.104 _VADGFK(gl)VVAR_
GMPS Ubiquitylation K182 0.575 0.078 _SGNIVAGIANESK(gl)K_
GMPS Ubiquitylation K183 0.652 0.078 _SGNIVAGIANESKK(gl)_
GMPS Ubiquitylation K288 0.285 _ESQSVEEALK(gl)K_
GMPS Ubiquitylation K289 -0.344 0.223 _K(gl)LGIQVK_
GMPS Phosphorylation T330 -0.017 _TLNM(ox)T(ph)TSPEEK_
GMPS Phosphorylation T331 0.917 _TLNMTT(ph)SPEEK_
GMPS Phosphorylation S332 0.573 0.448 _TLNMTTS(ph)PEEK_
GMPS Ubiquitylation K457 -0.834 _VICAEEPYICK(gl)DFPETNNILK_
HPRT1 Phosphorylation S5 -0.474 _S(ph)PGVVISDDEPGYDLDLFCIPNHYAEDLER_
HPRT1 Ubiquitylation K103 0.354 -0.199 _LK(gl)SYCNDQSTGDIK_
HPRT1 Ubiquitylation K159 0.923 0.525 _MVK(gl)VASLLVK_
HPRT1 Ubiquitylation K166 -0.029 -0.428 _VASLLVK(gl)R_
HPRT1 Ubiquitylation K175 -1.570 _SVGYK(gl)PDFVGFEIPDK_
HPRT1 Ubiquitylation K215 0.354 -0.516 _DLNHVCVISETGKAK(gl)_
IMPDH1 Phosphorylation T6 -0.746 -1.087 _(ac)M(ox)EGPLT(ph)PPPLQGGGAAAVPEPGAR_
IMPDH1 Ubiquitylation K293 0.154 0.299 _GK(gl)LPIVNDCDELVAIIAR_
IMPDH1 Ubiquitylation K327 2.285 1.616 _DSQK(gl)QLLCGAAVGTR_
IMPDH1 Ubiquitylation K507 0.433 _GMGSLDAMEK(gl)SSSSQKR_
IMPDH1 Ubiquitylation K523 0.629 _YFSEGDKVK(gl)_
IMPDH1 Ubiquitylation K535 0.179 -0.096 _IAQGVSGSIQDK(gl)GSIQK_
IMPDH2 Ubiquitylation K124 0.058 _YEQGFITDPVVLSPK(gl)DR_
IMPDH2 Ubiquitylation K134 0.709 0.285 _VRDVFEAK(gl)AR_
IMPDH2 Phosphorylation S160 0.758 0.744 _LVGIISS(ph)R_
IMPDH2 Ubiquitylation K208 -0.482 -0.007 _GK(gl)LPIVNEDDELVAIIAR_
IMPDH2 Ubiquitylation K293 0.119 _DK(gl)YPNLQVIGGNVVTAAQAK_
IMPDH2 Phosphorylation S416 0.362 0.652 _GMGS(ph)LDAMDK_
IMPDH2 Ubiquitylation K422 1.114 0.582 _GMGSLDAMDK(gl)HLSSQNR_
IMPDH2 Ubiquitylation K450 0.313 0.467 _VAQGVSGAVQDK(gl)GSIHK_
ITPA Ubiquitylation K18 0.644 _IVFVTGNAK(gl)K_
ITPA Ubiquitylation K19 0.644 _IVFVTGNAK(gl)K_
TK1 Phosphorylation S13 -1.350 -1.354 _(ac)SCINLPTVLPGS(ph)PSK_
TK1 Phosphorylation S15 -1.567 -1.084 _SCINLPTVLPGSPS(ph)K_
TK1 Ubiquitylation K16 -1.664 _(ac)SCINLPTVLPGSPSK(gl)TR_
UCK1 Phosphorylation T256 1.212 0.752 _RT(ph)FSEPGDHPGM(ox)LTSGK_
UCK1 Phosphorylation S258 0.987 0.574 _TFS(ph)EPGDHPGMLTSGK_
UCK2 Ubiquitylation K75 0.162 _VLTSEQKAK(gl)_
UCK2 Ubiquitylation K99 -0.004 -0.101 _TLK(gl)EITEGK_
UCK2 Ubiquitylation K202 -1.119 _K(gl)YADVIIPR_
UCKL1 Phosphorylation T53 -0.848 -0.530 _LLPPVGT(ph)GRSPR_
UCKL1 Phosphorylation S56 -0.803 _LLPPVGTGRS(ph)PR_
UCKL1 Ubiquitylation K328 -1.339 _TLSVLK(gl)STPQVR_
UCKL1 Ubiquitylation K392 -0.829 _CYAGK(gl)QITGVSILR_
UCKL1 Ubiquitylation K510 -0.370 -0.079 _IITTAVDK(gl)R_


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